子宫恶性中胚叶混合瘤22例临床分析  

Clinical analysis of uterine malignant lerian mixed tumors 22 cases

作　　者：张玉梅[1] 胡秀萍[1] 

机构地区：[1]南京医科大学附属淮安第一医院妇科,江苏南京223300

出　　处：《医药论坛杂志》2011年第23期54-55,58,共3页Journal of Medical Forum

摘　　要：目的通过22例子宫恶性中胚叶混合瘤的临床资料,探讨其发病相关因素及诊治方法。方法回顾性分析1988年1月—2007年6月南京医科大学附属淮安第一医院收治的22例子宫恶性中胚叶混合瘤的临床资料。结果 5年总生存率31.7%。癌肉瘤5年生存率37.8%,中胚叶混合瘤5年生存率31.2%、Ⅰ、Ⅱ期患者5年生存率55.5%,Ⅲ、Ⅳ期生存率9.1%,子宫体积大于妊娠10周,5年生存率为0%,小于10周者,5年生存率49.2%,已绝经者5年生存率37.2%,高于未绝经组34.2%,放疗组高于化疗组。结论子宫恶性中胚叶混合瘤生存率与手术分期、子宫大小有密切关系,与病理类型、是否绝经无明显关系,术后辅以放疗对提供生存率有帮助。Objective To evaluate the prognostic factors and treatment methods of 22 uterine malignant lerian mixed tumor.Methods Totally 22 cases of the uterine malingnant lerian mixed tumor were collected for this retrospective study from1988 to 2007.Results The overall 5-year survival rate was 31.7%,37.8% carcinosarcomas and 31.2% in malignant mesodermal mixed tumors respectively（P0.05）.The 5-year survival rates of lesions limited to the uterus（stageⅠ＋Ⅱ）,and that of pelvic cavity invasion（stage Ⅲ） with distant metastases（stage Ⅳ） were 55.5% and 9.1% respectively（P0.01）.When the uterus was smaller than a pregnant uterus of 10 weeks,the 5-year survival rates was 49.2% while that of larger than a 10 weeks pregnant uterus was 0%（P0.01）.5-Year survival for premenopausals and postmenopausals were 37.2% and 34.2% respectively（P0.05）.radiotherapy group chemoembolization group.Conclusions The prognosis of uterine malignant lerian mixed tumor is significantly associated with surgicopathological stage and uterine size.It is not significantly crrelated with histologic type and pre-or postmenopausal status.A combination of surgery and radiotherapy can be helpful to enhance the survivals.

关 键 词：子宫恶性中胚叶混合瘤 生存率 治疗 

分 类 号：R737.33[医药卫生—肿瘤]