VDP与VDLP方案治疗急性淋巴细胞白血病疗效分析  

THE CURATIVE EFFECT OF 67 PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA IN VDP OR VDLP REGIMENS

作　　者：狄黎明[1] 邵剑峰[1] 付佳萍[1] 封蔚莹[1] 何薇[1] 

机构地区：[1]浙江省绍兴市人民医院,浙江绍兴312000

出　　处：《白血病》2000年第1期31-32,共2页

摘　　要：目的 :观察 VDP与 VDL P方案对成人急性淋巴细胞白血病 ( AL L )诱导化疗的疗效。方法 :将 67例诊断明确的成人 AL L 分为两组 ,分别用 VDP与 VDL P方案行诱导化疗 ,用 χ2检验进行统计学处理。结果 :VDP与VDL P诱导化疗后 ,其 CR率分别是 60 .71%和 84 .62 % ( χ2 =4 .74 ,P<0 .0 5 ) ,两组之间疗效有显著性差异。且骨髓抑制方面无显著性差异 ( χ2 =2 .10 ,P<0 .0 5 )。结论 :VDL P可作为成人 AL LObjective:To compare the response of VDP or VDLP inducing chemotherapy to acute lymphoblascic leukomia (ALL). Methods: 67 adult patients with ALL mere randomized into two gronps (VDP group and VDLP group)VDP contained chemotherapy agents of daunorubicin,VCR, prednisone,VDLP contained chemotherapy agents of daunorubicin,VCR,prednisone,L Aase.Chi square method was used in the statistical disposal.Results: To the VDP and VDLP inducing chemotherapies,the complete remission rate was 60.71% and 84.62%(χ 2=4 74, P <0 05).There was signifilant difference of therapentic effect between the two gronps,but in the suppression of bone marrow,there was no significane difference(χ 2=2.10, P <0.05).Conclusion:VDLP programme can be the first belected to the treament of ALL.

关 键 词：VDP方案 VDLP方案 白血病 急性 治疗 

分 类 号：R733.71[医药卫生—肿瘤]