肺癌术后化疗患者的癌因性疲乏及影响因素研究  

Cancer-related fatigue in lung cancer patients receiving chemotherapy after surgery and its related factors

作　　者：粱骊敏[1] 刘雪莲[2] 廖英桃[3] 张美芬[4] 张俊娥[4] 

机构地区：[1]中山大学附属第三医院护理部,广州510630 [2]中山大学附属第三医院耳鼻喉科,广州510630 [3]中山大学附属第三医院心理科,广州510630 [4]中山大学护理学院

出　　处：《中华现代护理杂志》2012年第1期38-41,共4页Chinese Journal of Modern Nursing

摘　　要：目的描述肺癌术后化疗患者的癌因性疲乏水平，探讨其影响因素，旨在为制定有效的疲乏干预措施提供理论依据。方法采用描述性相关性研究设计，方便抽样的方法，采用Piper疲乏修正量表、抑郁自评量表、匹兹堡睡眠质量指数量表对广州市2家三级甲等医院的100例肺癌患者的癌因性疲乏水平、抑郁水平、睡眠质量进行调查。结果87％肺癌术后化疗患者存在癌因性疲乏，呈中等水平；83％患者存在抑郁情绪，且抑郁程度越高，患者的CRF水平越高。患者术前疲乏总分为（4．72±0．88）分，术后为（5．44±1．26）分，组间比较差异具有统计学意义（t=11．98，P〈0．01）。患者睡眠质量PSQI评分总分为（11．00±3．85）分，患者的睡眠质量较差，且影响其CRF的水平，肺癌患者的CRF总分与睡眠质量的得分呈正相关（r=0．234，P〈0．05）。结论肺癌术后化疗患者普遍存在癌因性疲乏，医护人员应关注肺癌患者的情绪和睡眠质量，尽可能创造条件减轻患者的疲乏。Objective To describe the level of cancer related fatigue （CRF） in lung cancer patients receiving chemotherapy after surgery, and to explore its related factors so as to provide the basis for making effective intervention measures. Methods 100 lung cancer patients receiving chemotherapy after surgery from two tertiary-level hospitals were recruited in this study by convenient sampling. The study adopted a descriptive correlation method. The level of CRF and depression, and sleep quality were investigated with the Revised Piper Fatigue Scale, Self-Rating Depression Scale（ SDS）, and Pittsburgh Sleep Quality Index（PSQI）. Results 87% of lung cancer patients had a middle level of CRF, ; 83% of them had depression, the higher the level of depression, the higher the level of CRF. The total score of fatigue before the operation was （4. 72 ± 0. 88 ）, （ 5.44 ± 1.26） after the operation; there was significant difference between the score of fatigue before and after the operation（ t = 11.98, P 〈 0.01 ）. Patients＇ total score of PSQI was （ 11.00 ± 3.85） ; their sleep quality was poor, and it also influenced the levels of CRF. The total score of CRF is positively related with the sleep quality （r = O. 234, P 〈 0. 05 ）. Conclusions CRF prevails in lung cancer patients receiving chemotherapy after surgery, the medical care staff shall pay much attention to their emotion and sleep quality so as to lessen their fatigue as much as possible.

关 键 词：肺肿瘤 癌因性疲乏 睡眠质量 

分 类 号：R730.6[医药卫生—肿瘤]