3368例武汉市儿童幽门螺杆菌感染的临床分析  

Clinical analysis of Helicobacter pylori infection of 3368 children in Wuhan

作　　者：李红艳[1] 邓涛[1] 占义军[1] 皮小雨[1] 

机构地区：[1]武汉大学人民医院消化内科,湖北武汉430060

出　　处：《胃肠病学和肝病学杂志》2012年第1期63-65,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的了解武汉市有消化道症状的儿童幽门螺杆菌感染状况、分布特征及影响因素。方法选取我院及武汉市医院2010年8月～2011年7月3 368例有消化道症状的儿童,以性别和年龄进行分组,通过14 C-尿素呼气试验检测幽门螺杆菌感染情况,并对其结果进行统计学分析,同时对这些儿童的生活方式进行问卷调查分析。结果 3 368例受检儿童H.pylori总感染率为29.2%,其中男女儿童H.pylori感染阳性率分别为29.2%和29.1%,男女儿童H.pylori感染阳性率差异无统计学意义(P>0.05);学龄前、学龄期及青春期儿童H.pylori感染阳性率分别为27.1%、28.7%和39.1%,学龄前期与学龄期H.pylori感染阳性率差异无统计学意义(P>0.05),学龄前期、学龄期与青春期H.pylori感染阳性率差异有统计学意义(P<0.01);年龄与H.pylori感染阳性率相关(P=0.001);同年龄组男女儿童H.pylori感染阳性率差异无统计学意义(P>0.05);父母幽门螺杆菌阳性患儿幽门螺杆菌阳性率57.5%。结论武汉市有消化道症状的儿童幽门螺杆菌感染率高,随年龄增长感染率递增,但与性别无关,父母幽门螺杆菌阳性患儿幽门螺杆菌阳性率高,年龄、家庭聚集性、父母H.pylori感染与儿童H.pylori感染相关。Objective To investigate the prevalence of Helicobacter pylori（H.pylori） infection,distribution and related factors in the children with digestive tract symptom in Wuhan.Methods Grouping was conducted based on gender and age.H.pylori infection was detected by 14C-ura breath test（14C-UBT）.The resulting data was statistically analyzed.Results H.pylori-positive rate in 3 368 children was 29.2%,and the positive rates in boys and girls were 29.2% and 29.1%.There was no significant difference in the positive rate between the boys and girls（P0.05）.Positive rates of H.pylori in preschool and school-age children were 27.1% and 28.7%,respectively,the postive rate of H.pylori in adolescent children was 39.1%（P0.05）.There was no significant difference in the positive rate between the preschool children and school-ager children（P0.05）.There were significant differences in the positive rates between the preschool children and the adolescent children,the school-ager children and the adolescent children.The positive rate of H.pylori had positive relation with age（P=0.001）,but not sex.The positive rate of Helicobacter pylori was 57.5% in children with H.pylori infection parents.Conclusion Helicobacter pylori infection rate was high in the children with digestive tract symptom in Wuhan,and infection rate increased with increasing age.It was high in those children with H.pylori infection parents.

关 键 词：儿童 14C-尿素呼气试验 幽门螺杆菌 

分 类 号：R573.6[医药卫生—消化系统]