^(18)F-FDG PET/CT显像在结直肠癌术前分期中的价值  

The Diagnostic Value of ^(18)F-FDG PET/CT Imaging in Preoperative Staging of Colorectal Cancer

作　　者：王大龙[1] 于丽娟[2] 田墨涵[2] 任美丽 张士德[1] 高波[1] 

机构地区：[1]哈尔滨医科大学附属第二医院放射线科,150086 [2]哈尔滨医科大学附属第三医院PET/CT中心 [3]沈阳军区沈司第二干休所

出　　处：《临床放射学杂志》2012年第1期70-74,共5页Journal of Clinical Radiology

基　　金：黑龙江省自然科学基金资助项目(编号:D200863);哈尔滨市科技创新人才研究专项资金项目(2011RFXYS061)

摘　　要：目的探讨18F-FDG PET/CT在结直肠癌术前TNM分期中的应用价值。资料与方法 33例疑结直肠肿瘤患者均于手术治疗前行全身PET/CT扫描,将患者PET/CT检查结果与手术病理学检查结果进行比较分析。结果 PET/CT诊断结直肠癌原发灶的敏感性、准确性分别为100%和96.97%;PET/CT对术前结直肠癌侵犯局部浆膜、淋巴结转移、远处转移及TNM分期的准确性分别为75.00%、78.12%、96.87%和71.87%,经Kappa一致性检验,PET/CT上述诊断结果与手术病理学检查结果具有较好的一致性(0.429,0.559,0.920,0.619,P均<0.05)。结论结直肠癌18F-FDG PET/CT术前检查,是结直肠癌的术前临床分期中有效的影像学评价手段。Objective To evaluate the value of 18F-FDG PET/CT on the TNM staging of colorectal cancer before surgery.Materials and Methods 33 patients with colorectal tumor received 18F-FDG PET/CT before surgery.PET/CT findings were compared with pathological results and statistical analysis were performed.Results The sensitivity,accuracy of diagnosing primary colorectal lesions was 100%,96.97% respectively by PET/CT.The diagnostic accuracy of local chorion invasion and Lymph node metastasis and distant metastasis and TNM stage before operation in colorectal cancer were 75.00%,78.12%,96.87%,71.87% respectively,and the correlation with pathological results were 0.429,0.559,0.920,0.619,respectively（P0.05）.Kappa coefficients showed that the correlation between manifestations on PET/CT and operative pathology were good.Conclusion PET/CT is an effective diagnostic imaging method in evaluating the staging of colorectal carcinomas before surgery.

关 键 词：结直肠癌 分期 PET/CT 

分 类 号：R735.3[医药卫生—肿瘤]