可吸收胶原生物膜用于齿槽裂植骨修复临床疗效研究  

Clinical application of absorbable collagen bio-membrane to the bone graft repair of alveolar cleft

作　　者：李志强[1] 艾伟健[1] 刘曙光[1] 

机构地区：[1]广东省口腔医院南方医科大学附属口腔医院,广州510280

出　　处：《中国实用口腔科杂志》2012年第1期41-43,共3页Chinese Journal of Practical Stomatology

摘　　要：目的探讨可吸收性胶原生物膜应用于齿槽裂植骨修复的临床效果。方法选择2006—2009年在广东省口腔医院口腔颌面外科就诊的单侧齿槽裂患者108例,年龄9~13岁,随机分为2组。对照组60例单纯应用髂骨松质骨行植骨修复,试验组48例应用髂骨松质骨加可吸收胶原生物膜覆盖行植骨修复。术后1周及3、6、12个月行X线检查。结果试验组植骨成活率和临床成功率（97.9%、79.2%）高于对照组（86.7%、58.3%）,差异有统计学意义（P〈0.05）。结论自体髂骨加可吸收胶原生物膜联合应用于齿槽裂植骨修复中,可有效提高植骨成功率,为后续治疗提供更好保障,值得临床推广。Objective To investigate the clinical effects of absorbable collagen bio-membrane in the bone graft repair of alveolar cleft. Methods Totally 108 patients aged 9-13 years with alveolar cleft who were treated in Guangdong Provin cal Stomatological Hospital between 2006 to 2009 were included,and they were divided into control group（n = 60）using cancellous tissue of iliac bone and experimental group（n = 48）using cancellous tissue of iliac bone combined with ab sorbable collagen bio-membrane. Patients were followed up postoperatively,radiographs taken in 1 week,3,6,12 months and their treatment effect evaluated. Results The overall survival rate and the clinical success rate of the bone graft in experimental group were 97.9% and 79.2%,which were higher than those in control group（86.7 % and 58.3%）. There was significant difference between the two groups（P 〈 0.05）. Conclusion The application of cancellous tissue of iliac bone combined with absorbable collagen bio-membrane is a better method in the bone graft repair of alveolar cleft.

关 键 词：齿槽裂 骨移植 胶原生物膜 自体骨 

分 类 号：R78[医药卫生—口腔医学]