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出 处:《肿瘤基础与临床》2012年第1期50-51,共2页journal of basic and clinical oncology
摘 要:目的探讨胰腺类癌的临床病理学特点。方法对手术治疗的8例胰腺类癌患者临床病理资料进行回顾性分析。结果肿瘤标志物CEA、CA199、CA125、CA724在胰腺类癌组织中的阳性率分别为0.0%,25.0%,12.5%,0.0%;免疫组化染色Syn、CgA、NSE、CK阳性率分别为25.0%、62.5%,75.0%,75.0%。胰腺类癌误诊率较高,8例患者中有7例误诊为其他肿瘤。结论胰腺类癌误诊率高,临床预后较差,常规血液肿瘤标志物检测对早期发现胰腺类癌意义不大,确诊需要病理及免疫组化学检查。Objective To explore the clinical and pathological characteristics of pancreatic carcinoid. Methods The clinical data of 8 patients with pancreatic carcinoid were analyzed retrospectively. Results The positive rates of CEA,CA199,CA125 and CA724 in pancreatic carcinoid were 0.0%,25.0%,12.5% and 0.0%,respectively.The positive rates of Syn,CgA,NSE,and CK in pancreatic carcinoid were 25.0%,62.5%,75.0% and 75.0%,respectively.The misdiagnosis rate of pancreatic carcinoid was markedly high,7 cases from the 8 cases were misdiagnosed for other tumors. Conclusion pancreatic carcinoid has the high misdiagnosis rate and the poor prognosis,routine blood tumor markers can't help discover pancreatic carcinoid early,the final diagnosis depends on specimen immunohistostaining.
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