心包内处理肺血管肺切除术治疗肺癌130例疗效分析  

Pneumonectomy with intrapericardial ligation of the pulmonary artery and vein:analysis of 130 patients with advanced lung cancer

作　　者：罗国军[1] 庄江能 李卓东[1] 凃东 石云[1] 刘鑫[1] 

机构地区：[1]成都军区昆明总医院心胸外科,昆明650032 [2]解放军第62医院,普洱665000

出　　处：《肿瘤》2012年第2期134-136,共3页Tumor

摘　　要：目的:评价通过心包内血管处理行肺切除术治疗中晚期肺癌的临床疗效。方法:2006年4月—2011年4月在本院接受心包内血管处理肺切除术的130例中晚期肺癌患者,观察术后并发症和手术死亡率,并分析不同病理分型和TNM分期对生存的影响。结果:手术死亡率为0.77%(1/130),术后并发症发生率为14.6%(19/130)。全组患者的1、3和5年生存率分别为75%、43%和20%。行肺叶切除患者的1、3和5年的生存率均高于全肺切除患者(P<0.01)。行心包内血管处理左肺全切术患者的1、3和5年的生存率要高于心包内右肺全切术后患者(P<0.01)。结论:通过心包内血管处理行肺切除术治疗中晚期肺癌可增加手术切除范围并提高手术切除率,改善患者的术后生存。Objective：To evaluate the clinical outcomes of pneumonectomy with intrapericardial ligation of the pulmonary artery and vein in patients with advanced lung cancer.Methods：The clinical records of 130 patients undergoing pneumonectomy with intrapericardial ligation of the pulmonary artery for advanced lung cancer diagnosed between April 2006 and April 2011 were collected and reviewed.The postoperative morbidity and the operative mortality were analyzed,and the associations between the survival and the pathology and TNM staging were evaluated.Results：The operative mortality was 0.77%（1/130）,and the postoperative morbidity was 14.6%（19/130）.The overall one-,three and five-year survival rates were 75%,43% and 20%,respectively,and those were all higher in the patients receiving lung lobectomy than in the patients receiving pneumonectomy（P0.01） and also higher in the patients receiving left lobectomy than in the patients receiving right lobectomy（P0.01）.Conclusion：Pneumonectomy with intrapericardial ligation of the pulmonary artery and vein can extend the resection range and increase the resection rate of advanced lung cancer,as well as improve the postoperative survival.

关 键 词：肺肿瘤 肺动脉和静脉 心包内 肺切除术 

分 类 号：R734.2[医药卫生—肿瘤]