颌骨黏液瘤临床与病理研究  

Clinical-pathologic Study of Myxoma of the Jaws

作　　者：陈菲[1] 陆东辉[2] 陈湘华[1] 张庆庆[3] 邓润智[2] 王三锡[4] 

机构地区：[1]南京大学医学院附属口腔医院病理科,江苏南京210008 [2]南京大学医学院附属口腔医院口腔颌面外科 [3]南京大学医学院附属口腔医院放射科 [4]南京医科大学病理教研室

出　　处：《口腔医学研究》2012年第2期167-169,共3页Journal of Oral Science Research

摘　　要：目的:总结颌骨黏液瘤临床、病理特点。方法:对29例颌骨黏液瘤的临床表现、X线影象及病理特征等进行回顾性分析。结果:29例中男9例,女20例,平均年龄31.8岁;病变位于下颌骨17例,上颌骨12例;临床多以颜面部肿胀而就诊。X线常表现为边界不清的多房性泡沫状透光影,其中间杂有不透光区。该瘤的组织病理学特征,主要是在黏液样基质中散在分布一些星芒状、梭形、三角形的瘤细胞。镜下依据胶原纤维的含量分为(纤维)黏液瘤(15例)和黏液纤维瘤(14例)2种类型。结论:临床上颌骨黏液瘤与其他一些颌骨病变很难鉴别,最后确诊仍需病理检验。通过分析表明,该瘤预后相对较好,但由于其具有局部浸润性,黏液纤维瘤型及保守性手术如刮治术不彻底可复发。Objective：To study the clinic and pathology of odontogenic myxoma（OM） of the jaws. Methods：The datas including clinical, X-ray, histologie features of 29 cases of OM of the jaws were reviewed and analyzed retrospectively. Results：Among the 29 cases of OM, male 9 and female 20, with the mean age 31.8. The location of the lesion was limited in this study： 17 cases were in the mandible, while 12 were in the maxilla. The majority of cases had presented facial swelling clinically. Radiographieally, OM had been described classically as extensive destruction of bone and produced irregular, multilocular and diffusible radiolucencies with clear or unclear borders and variable amounts of radiopaque materials. OM showed stellate, spindle--shaped and triangular mesenchymal cells embedded in a loose mucoid matrix in pathological changes. According to the amount of collagen, the tumor was subdivided into fibromyxoma in 15 cases and myxofibroma in 14 cases. Conclusion：The differential diagnosis was important as OM always confused with other lesions of the jaws. Making a definite diagnosis relied on pathological changes. Its prognosis was relatively good , but because of its invasive nature, myxofibroma and conservative operations such as curettage seemed more inclined to recurrence through the analyses.

关 键 词：颌骨 黏液瘤 (纤维)黏液瘤 黏液纤维瘤 临床病理 

分 类 号：R739.8[医药卫生—肿瘤]