基于MRI和CT图像配准的颅内电极定位方法  

Intracranial electrode localization based on MRI and CT image registration

作　　者：李丹妮[1] 董硕[1] 柳渊[1] 严汉民[1] 

机构地区：[1]首都医科大学宣武医院医学工程科,北京100053

出　　处：《生物医学工程与临床》2012年第1期7-10,共4页Biomedical Engineering and Clinical Medicine

摘　　要：目的应用多模医学图像配准,在颅内电极埋置术后对颅内电极进行精确定位。方法通过对颅内电极埋置前的头颅MRI图像和埋置后头颅CT图像进行配准,利用医学影像配准与分割工具包(ITK),将颅内电极位置准确地定位在MRI图像上,以建立电极位置与大脑解剖结构的联系。结果经过对10组断层图像进行配准定位,差值图像显示匹配程度较好,专家目测融合效果较为精确。在普通PC机上,以笔者所采用的数据为例,设定优化器初始步长为1,松弛因子为0.6,最小步长为0.000 2,最大迭代次数为100,整个电极定位的操作过程时间不超过1 min。结论多模医学图像配准对颅内电极定位较为准确,为医生提供了更加直观和完善的信息。Objective To accurately locate the intracranial electrode with the application of multimodal medical image registration after intracranial electrode embedding.Methods The intracranial electrode was accurately located in the magnetic resonance imaging（MRI） images by registration of MRI images before electrode embedding with CT images after electrode embedding and insight segmentation and registration toolkit（ITK）,and established the relationship between electrode location and brain anatomy.Results Ten pairs of slice images were used to evaluate the efficacy of the method and the data from the difference images after registration showed a good match,while the evaluation given by experts showed that the accuracy of image fusion was clinically acceptable.Conclusion It is demonstrated that multimode image registration is useful to localize the intracranial electrodes,providing physicians with a more intuitive and complete information.

关 键 词：癫痫手术 颅内电极定位 影像配准与分割工具包 多模图像配准 

分 类 号：R742.1[医药卫生—神经病学与精神病学]