四联疗法清除幽门螺杆菌疗效观察  

作　　者：隋淑静[1] 姚慧静[1] 

机构地区：[1]山东泰安市中心医院消化内科,271000

出　　处：《中国社区医师（医学专业）》2012年第5期127-128,共2页

摘　　要：目的:探讨四联疗法对幽门螺杆菌(Hp)的根除效果。方法:将220例Hp感染的患者按就诊顺序随机分为两组。试验组121例,给予口服四联疗法,泮托拉唑、胶体果胶铋、左氧氟沙星、甲硝唑;对照组99例予口服三联疗法:泮托拉唑、阿莫西林、克拉霉素。两组均口服10天,观察服药后不良反应。结果:疗程结束后4周,复查胃镜及幽门螺杆菌。清除率:试验组93.4%(113/121),对照组80.8%(80/99)。两组比较差异有统计学意义。结论:观察组四联疗法的效果优于对照组三联疗法。Objective：to explore the quadruple therapy on HP（Helico bacter pylori,Hp） the eradication effect.Methods：220 cases of Hp infection in patients with a doctor ordered randomly divided into two groups.The contrasts of 121 cases,oral quadruple therapy：pantoprazole,Colloidal bismuth pectin,left-ofloxacin and metronidazole;Control group of 99 case,oral triple therapy：pantoprazole,and amoxicillin and clarithromycin.Two sets of oral administration of 10 days,after observation of medication side-effects.Results：4 weeks after the end of the course,review the gastroscope and HP.Clearance：the contrasts of 93.4% One hundred and thirteen-one hundred and twenty firsts,the control group（80.8%）.Two sets of comparison differences are statistically significant.Corclusion：Observation quadruple therapy performed better than control groups of triple therapy.

关 键 词：幽门螺杆菌 药物疗效 

分 类 号：R573.1[医药卫生—消化系统]