认知疗法合并艾司西酞普兰治疗女性抑郁症患者的疗效  

Effects of S-citalopram associated with cognitive therapy in the treatment of women depression

作　　者：刘秀苹[1] 雷彤[1] 刘丽荣[1] 

机构地区：[1]天津市安定医院,300222

出　　处：《临床精神医学杂志》2012年第1期52-53,共2页Journal of Clinical Psychiatry

摘　　要：目的:比较艾司西酞普兰合并认知治疗与单用艾司西酞普兰对女性抑郁症患者的疗效。方法:60例女性抑郁症患者随机分为研究组(艾司西酞普兰合并认知治疗组)30例,对照组(单用艾司西酞普兰组)30例,治疗8周。治疗前及治疗1、2、4和8周分别采用汉密尔顿抑郁量表(HAMD)评定疗效。结果:治疗2周开始,两组HAMD评分均显著下降。研究组治疗1周HAMD明显下降。研究组较对照组HAMD下降更显著。两组不良反应差异无显著性。结论:艾司西酞普兰合并认知治疗对女性抑郁症患者疗效明显,安全性高。Objective：To evaluate the clinical effects of S-eitalopram assoeiatedted with cognitive therapy in the treatment of women with depression. Method：60 women patients with depressive disorder were randomly divided into S-eitalopram associated with cognitive treatment group （ n = 30 ） and single S-eitalopram group （ n = 30） for 8 weeks. The efficacy was evaluated with Hamilton depression rating scale （ HAMD at baseline and 1,2,4 and 8-week treatment. Results：There was significant difference in total score of HAMD after two weeks. Research group shows significant effects after one week. There was significant difference in total score after the 1 st ,2nd ,4th, 8th week between two groups, Research group decreased more significantly, difference was not significant in side effect. Conclusion： S-citalopram assoeiatedted with cognitive therapy in the treatment of women is an effective and well-tolerated methed, can improve the effect and shorter the duration.

关 键 词：认知疗法 艾司西酞普兰 女性抑郁症 

分 类 号：R749.4[医药卫生—神经病学与精神病学]