肝硬化患者消化性溃疡合并出血的特点及治疗探讨  

POSTHEPATIC CIRRHOSIS PATIENTS COMBINED WITH PEPTIC ULCER AND TO EVALUATE THE CURATIVE EFFECT

作　　者：刘建生 鲍念慈[2] 

机构地区：[1]上海市闵行区中心医院 [2]上海市同仁医院

出　　处：《医师进修杂志》2000年第3期32-33,共2页Journal of Postgraduates of Medicine

摘　　要：目的；研究乙肝后肝硬化患者消化性溃疡合并出血的临床特点，探索小剂量心得安对肝源性溃疡并出血的疗效。方法：肝源性溃疡并出血４３例。观察其出血方式，病变部位等临床特点，并随机分为治疗组（Ａ组）２２例，用心得安和泰胃美＋基础治疗；对照组２１例，用维生素Ｂ６和泰胃美＋基础治疗；另外选单纯性消化性溃疡并出血２０例作为对照２组，治疗方法与Ｂ组相同。结果：肝源性溃疡以胃溃疡居多，合并出血时难以止血。Objective:To study the clinical characters of gastrointestinal tract bleedings occured in the posthepatic cirrhosis patients combined with peptic ulcer and to evaluate the curative effect of prapanolol on these patients.Methods:43 cases of hepatic ulcer combined with bleeding were randomly divided into two groups:group A(22 cases) were treated with prapanolol,tagamet and basic therapy;group B (21 cases) were treated with Vitamin B 6,tagamet and basic therapy.We also had so cases of simple peptic ulcer as costrds which were treated in the same way of group B.Results:Most cases of hepatic ulcer were gastric ulcer.It was difficult to hemostasis while bleeding.Comparing with group B,group A had the obvionsly shortened mea hemostatic time (P<0.01) and increased effective rate of hemostasis (P<0.05).Conclusions:Difficulty of hemostasis in hepatic ulcer is probably due to portal hypertension and small dose of prapanolol is meful for hemostasis in hepaticulcer.

关 键 词：肝硬化 消化道出血 消化性溃疡 治疗 特点 

分 类 号：R575.2[医药卫生—消化系统] R573.1[医药卫生—内科学]