慢性结肠炎等疾病患者的大便异常与结肠电频谱改变  

Abnormality of Stool and Electrocolonogram Spectrum in Patients with Chronic Colitis

作　　者：梁雪芬[1] 陈苇菁[1] 杨巧红[1] 谢海燕[2] 杨立红[1] 苏宁[2] 连至诚[1] 

机构地区：[1]广州中医药大学脾胃研究所,广州510405 [2]广州中医药大学基础医学院,广州510405

出　　处：《广州中医药大学学报》2000年第1期76-80,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金!资助项目 (No . 3870 194);国家中医药管理局资助!项目 (N0 . 95 10 990 9);广东省自然科学基金资助!课题 (No . 9

摘　　要：为探讨慢性结肠炎等疾病患者的大便异常与结肠电频谱改变的关系 ,对 114例患者临床观察发现 ,消化道疾病患者有大便异常或倾向的比率颇高 ,所占比率从高至低依次为慢性结肠炎 (CS ,80 .0 % ) >十二指肠溃疡 (DU ,6 9.2 % )及十二指肠炎 (DS ,6 8.7% ) >慢性胃炎 (GS ,54.8% )。CS组有腹泻倾向者占 56 .0 % ,便秘占 2 4 .0 % ;DS组便烂便频者亦占 4 3.8% ,都明显高于GS组及对照组。应用“微电脑胃肠电检测分析系统”作体表结肠电检查及频谱分析 ,发现GS组空腹升结肠低频段及餐后乙状结肠低频段结肠电明显减弱 ;DS组餐后三部结肠的低、高频段电活动及收缩性复合肌电都亢进或倾向异常增强 ;DU组空腹或餐后三部结肠的低、高频段电活动及收缩性复合肌电则明显或倾向减弱 ;CS组空腹乙状结肠低频段电活动明显减弱 ,而餐后升结肠低频段电活动则亢进。休表结肠电异常能部分解释不同类型大便改变的发生机制。空腹低频段结肠电减弱、餐后结肠电亢进的动力异常模式可能是CS等患者便烂、便频呈慢性腹泻倾向的重要机制。In 114 cases with gastrointestinal diseases,abnormal stool occurs in a sequence as follows: chronic colitis ( 80.0% ), duodenal ulcer ( 69.2% ), duodenitis ( 68.7% ) and gastritis ( 54.8% ). As shown by “Electrogastrogram Spectrum System”, the spectrum sum of low frequency electrical activity (SSLFE) of ascending and sigmoid colon in fasting state was significantly weaker in gastritis as compared with control. SSLFE, spectrum sum of high frequency electrical activity (SSHFE) and contractile electrical complex (CEC) after test meal were stronger in duodenitis. SSLFE, SSHFE and CEC of ascending, descending and sigmoid colon in fasting state and after meal were weaker in duodenal ulcer. And SSLFE of sigmoid colon in fasting state was weaker, and SSLFE of ascending colon after meal were stronger in chronic colitis. It was shown that the electrocolonogram spectrum may serve as a valuable criterion for the study of gastrointestinal dynamic diseases.

关 键 词：结肠炎 便秘 腹泻 胃肠活动 电生理学 

分 类 号：R574.62[医药卫生—消化系统]