MRI和1H-MRSI在颞叶癫痫中的对比研究  

Comparative studies on temporal lobe epilepsy by MRI and 1H-MRSI

作　　者：戴辉[1] 赖力[2] 周翰[2] 兰琦[2] 李忠[2] 付凯[2] 

机构地区：[1]遵义医学院附属医院放射科,贵州遵义563003 [2]四川省人民医院放射科,四川成都610072

出　　处：《四川医学》2012年第2期348-350,共3页Sichuan Medical Journal

摘　　要：目的探讨磁共振(MRI)和氢质子磁共振波谱成像('H-MRSI)对颞叶癲痫(TLE)的定位诊断价值。方法选择15例经临床表现和脑电图诊断的颞叶癫痫患者和15例健康志愿者为研究对象,一次性行MRI检查及两侧海马结构的1H-MRSI检查。结果 MRI发现5例患者单侧海马硬化。1H-MRS可对8例患者进行定侧诊断,其中3例有双侧颞叶病变。将两种检查方法结合起来可对10例准确定位。结论1H-MRS对颞叶癫痫定侧敏感性高于MRI,MRI诊断海马硬化特异性较高。两者相结合可提高术前定位的准确率。Objective To evaluate the value of MRI and 1H-MRSI in the lacalization diagnosis（LD）of temporal lobe epilepsy（TLE）.Methods 15 selected patients with TLE verified by clinical manifestations and diagnosis of EEG and 15 healthy volunteers were studied.One-time conventional MRI and bilateral hippocampus 1H-MRSI inspection.Results 5 of these patients showed unilateral hippocampus sclerosis.1H-MRSI of hippocampal was positive in 8 cases,3 cases showing bilateral abnormalities,combination of the two methods can accurate positioning of locases.Conclusion 1H-MRS was more sensitive than MRI in lateralizing seizure origin,and bilateral lesions can be foung but MRI was more specific than 1H-MRS.Combination of MRS with MRI can improve the accuracy ratio of the localization diagnosis.

关 键 词：颞叶癫痫 定位诊断 磁共振成像 磁共振波谱成像 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]