射波刀治疗颅内恶性肿瘤  

Intracranial malignant tumors treatment with CyberKnife

作　　者：张春智[1] 王平[2] 

机构地区：[1]天津环湖医院放疗科,300060 [2]天津市肿瘤医院放疗科,300060

出　　处：《国际放射医学核医学杂志》2011年第6期366-369,共4页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：国家自然科学基金（30901772）

摘　　要：在脑肿瘤放射治疗的过程中，需要特别关注放射损伤风险，其可能损害正常脑组织，从而造成认知障碍。射波刀对治疗靶的适形性好，且定位准确，因此，可以在分次较少的情况下完成整个治疗。射波刀治疗是迄今为止放射损伤的危险最小的治疗手段，其使得患者的生活质量得到了最大保护。射波刀已被证明了在治疗颅内常见恶性肿瘤性疾病转移瘤方面具有较好的应用价值，但它在治疗颅内恶性胶质瘤方面仍存争议。该文就射波刀在治疗肿瘤上的优势及其在恶性胶质瘤、脑转移瘤中的应用做相关综述。Of particular concern during radiosurgery of brain tumors is the risk of radiation damage to otherwise healthy tissue, potentially resulting in cognitive impairment. The conformality and precise targeting of the CyberKnife radiation beam enables this risk to be minimized to a greater extent than hitherto pos- sible, which may allow treatment to be completed in a small number of fractions, thereby improving the quality of life for patients. The CyberKnife has proven particularly valuable in the treatment of metastases, which represent the great majority of brain tumors, though its role in the management of malignant glial tumors remains a subject of controversy. This article reviews the published studies on the efficacy of CyberKnife radiosurgery for brain tumors of both glial and metastatic origin, and advantage in the management of malignant tumor.

关 键 词：胶质母细胞瘤 星形细胞瘤 脑转移瘤 放射外科手术 射波刀 

分 类 号：R739.41[医药卫生—肿瘤]