中国胰腺癌临床诊断标准的探讨  

Discussion for the clinical definition of pancreatic cancer in China

作　　者：倪泉兴 虞先濬[1,2] 刘亮 

机构地区：[1]复旦大学附属肿瘤医院胰腺肝胆外科 [2]复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国癌症杂志》2012年第2期81-87,共7页China Oncology

基　　金：国家自然科学基金(No:81172005);上海市自然科学基金(No:11ZR1407000);教育部高等学校博士学科点专项科研基金(新教师类;No:20110071120096);复旦大学附属肿瘤医院院级基金(No:YJ201002)

摘　　要：胰腺癌是目前消化道肿瘤中诊治最为困难,预后极差的恶性肿瘤。提高其诊治水平是改善胰腺癌预后的唯一途径。虽然取得病理学证据是确诊胰腺癌的关键,但由于胰腺解剖位置的特殊性及本身质地的"脆弱",患者主观上对胰腺癌的认识不足及对损伤性检查的恐惧,我国客观医疗环境如经济文化水平的差异,医疗条件及技术水平的参差不齐等诸多因素,临床获取病理学证据较为困难。不少患者因缺少病理诊断依据而丧失积极治疗的机会。因此,本文结合临床实践,制定出适合我国国情的胰腺癌临床诊断标准和分级标准,以期指导临床治疗方案的选择及提高我国胰腺癌诊治水平。Pancreatic cancer is one of the most lethal human cancers.Its diagnosis and treatment are difficult and lagged behind some other malignant tumors.Early diagnosis and improved treatment must become the standard of care for patients with pancreatic cancer.Despite evidence of pathology is the key to the diagnosis of pancreatic cancer,it is yet difficult to carry out due to the rationale as followed.First,the special nature of anatomical location of the pancreas and its ＂fragile＂ texture augment the risk of biopsy.Moreover,it is difficult to implement this measure since patients is lack of medical knowledge and fear of invasive examination.Third,Medical environment in China,such as the diversity of socioeconomic or cultural status and imparity of medical resources or services,lead to clinical evidence of pathology is more difficult to be obtained.In regard these,a considerable number of patients failed to receive active treatment due to the lack of pathological diagnosis.Therefore,a new clinical diagnostic criteria and grading standards of pancreatic cancer suitable for Chinese patients were introduced by us.Its purpose is to guide the clinical treatment options and improve the level of diagnosis and treatment of pancreatic cancer in China.

关 键 词：胰腺癌 临床诊断 标准 

分 类 号：R739.63[医药卫生—肿瘤]