计算机图像分析法测量内镜下病灶面积的初步研究  

Computer assisted endoscopic measurement for area of gastric lesions

作　　者：王志化[1] 张磊[1] 许建明[1] 孔德润[1] 罗玲玲[1] 

机构地区：[1]安徽医科大学第一附属医院消化内科,合肥230022

出　　处：《中华消化内镜杂志》2012年第2期74-77,共4页Chinese Journal of Digestive Endoscopy

摘　　要：目的 应用计算机软件进行内镜下病灶桶形畸变的校正及面积的测量,以寻求内镜下病灶面积准确、客观及简便的测量方法.方法 内镜下桶形畸变的校正采用Panaroma tool软件,病灶面积及相对测量误差的处理应用Image J软件：（1）体外试验内镜下病灶面积的计算机软件测量法,首先确立Panorama tool纠正桶形畸变的校正系数,以达到最小测量误差,第二步观察胃镜镜头与图像之间物距的变化对测量的影响.（2）利用计算机软件测量法测量胃溃疡患者的病灶面积,并与不同测量方法进行比较.结果 （1）当选择Panaroma tool校正系数为0.1时,内镜下桶形畸变校正后测量误差最小（3.76±2.13）％；（2）桶形畸变未校正前,随着胃镜镜头与图片距离的增加,测量相对误差逐渐增加；而通过Panaroma tool校正后,不同物距之间相对测量误差差异无统计学意义（P=0.141）；（3）对50例胃溃疡病灶进行测量,结果显示Panorama tool联合Image J软件处理后,所得溃疡面积（35.0±5.0）mm2大于传统公式法计算得出的面积（29.1 ±4.1）mm2,两者差异有统计学意义（P=0.000）,相关系数为0.988.结论 应用计算机图像分析法有望成为内镜下病灶面积测量相对准确,客观简便的方法.Objective To explore an accurate,objective and simple method for barrel distortion correction and lesion area measurement by assistance of computer.Methods The software of Panaroma tool was employed to correct barrel distortion of endoscopy and Image J to measure lesion size and manage the relative measurement error.Computed measurement in vitro of lesion area was established,firstly,by identification of correction factor of Panorama tool to minimize measurement error; then by determination of influence of object distance change between the lens and the image.This measurement was used on patients with gastric ulcer for focal area.Results were compared with those of traditional method.Results Number of 0.1was determined to be the correction factor for barrel distortion of endoscopy.Prior to the correction of the barrel distortion,the relative error of measurement gradually increased with the increasing distance between endoscopy and the image.However,different object distances did not exert influence on the relative measurement error when barrel distortion was corrected by Panaroma tool （ P =0.141 ）.A total of 50 foci of gastric ulcer were measured,results from combinational treatment of Panorama tool and Image J showed the areas （35.0 ± 5.0） mm2 were significantly larger than those determined by traditional method [ （ 29.1 ± 4.1 ） mm2,P =0.000 ],with a correlation coefficient of 0.988.Conclusion Computed endoscopic lesion measurement is a relatively accurate,objective and simple method to determine the area of gastric lesions.

关 键 词：内窥镜检查 计算机软件 面积测量 桶形畸变 

分 类 号：R57[医药卫生—消化系统]