化痰泻浊方联合饮食运动治疗对非酒精性脂肪性肝炎患者TG、ALT及BMI的影响  

Effect of Huatan Xiezhuo Recipe combined exercise and dietary treatment on TG/ALT/BMI levels in patients with nonalcoholic steatohepatitis

作　　者：赵文霞[1] 刘君颖[2] 孟祥林 

机构地区：[1]南京中医药大学,南京210046 [2]河南中医学院第一附属医院,郑州450000 [3]郑州市中医院,郑州450000

出　　处：《中华中医药杂志》2012年第3期654-656,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金："十一五"国家科技支撑计划常见病项目(No.2007BAI20B095)~~

摘　　要：目的:探讨化痰泻浊方联合饮食运动治疗方案对非酒精性脂肪性肝炎(NASH)患者TG、ALT及BMI的影响。方法:采用多中心、随机对照、优效性研究,从4个分中心共收集NASH患者202例,分为治疗组(101例)和对照组(101例),两组在健康教育、饮食运动基础上,治疗组使用中药饮片颗粒剂1剂/d;对照组使用多烯磷脂酰胆碱(易善复)胶囊,456mg/次,3次/d;疗程3个月,随访3个月。观察治疗、随访后甘油三酯(TG)、谷丙转氨酶(ALT)及身体质量指数(BMI)的变化。结果:治疗组在降低TG、ALT方面明显优于对照组(P<0.05),两组治疗后BMI均比治疗前下降,但组间比较无明显差异。结论:化痰泻浊方联合饮食运动治疗方案可有效改善NASH患者的TG、ALT和BMI。Objective： To assess the effects of Huatan Xiezhuo Recipe combined exercise and dietary treatment on triglyceride（TG）,serum alanine aminotransferase（ALT） levels,body mass index（BMI） in patients with non-alcoholic steatohepatitis（NASH）.Methods： In all,202 patients with NASH were collected from four sub-centers were randomly divided into treatment group（101cases） and control group（101 cases）.The patients of treatment group were treated for 3 months with a daily traditional Chinese medicine and the patients of control group were treated for 3 months with Polyene Phosphatidylcholine Capsules（Essentiale）,3 times each day,456mg/each time.Each patient was advised regular aerobic exercise and dietary modification.Results： The treatment group was significantly better than control group on improved TG and ALT levels（P〈0.05）,but BMI had no significant difference.Conclusions： The Chinese medicine combined exercise and dietary treatment could improved the TG,ALT,BMI levels of the patients of NASH.

关 键 词：化痰泻浊方 非酒精性脂肪性肝炎 甘油三酯 身体质量指数 

分 类 号：R575.1[医药卫生—消化系统]