短暂性脑缺血发作进展为脑梗死危险因素分析  

Analysis of Risk Factors for Cerebral Infarction Resulting from Transient Ischemic Attack

作　　者：许航[1] 冯敏[1] 寿广丽[1] 

机构地区：[1]蚌埠医学院第二附属医院神经内科,安徽省蚌埠市233040

出　　处：《中华全科医学》2012年第3期373-373,410,共2页Chinese Journal of General Practice

摘　　要：目的探讨短暂性脑缺血发作(transient ischemic attack,TIA)进展为脑梗死的相关危险因素。方法对133例TIA患者临床资料进行回顾性调查,根据以住院期间是否发生脑梗死,分为脑梗死组和非脑梗死组,详细记录两组的临床资料,包括TIA发作频率、发作持续时间、首次发作至治疗时间、发作次数至治疗时间以及血压、血糖、血胆固醇、甘油三酯等因素,并对两组的临床资料进行分析。结果 133例中48例发生了脑梗死,其中颈内动脉系统TIA 108例中39例发生脑梗死,椎基底动脉系统TIA 20例中7例发生脑梗死,同时累及两个系统者5例发生2例脑梗死,差异无统计学意义(P>0.05)。TIA发作的持续时间>30 min、发作频率>3次/d、首次发作距治疗时间>24 h或发作>5次开始治疗的TIA患者,脑梗死发生率明显增高,差异有统计学意义(P<0.05)。发生脑梗死的TIA患者血压、血糖、血脂显著增高(均P<0.05)。结论 TIA发作持续时间长、次数多、未及时治疗者短期内发生脑梗死的危险性较高。TIA患者如伴有高血压、高血糖、高脂血症的,在短期内发生脑梗死的危险性较高。Objective To evaluate the risk factors for cerebral infarction（CI） resulting from transient ischemic attack（TIA）. Methods The clinical data of 133 patients with TIA were evaluated. 133 TIA patients were divided into two groups according to occurring CI and（or） not CI：CI group and non-CI group. All were taken seizure frequency, seizure duration,onset to treatment time, the number of episodes to the treatment time and blood pressure, blood glucose, serum cholesterol, triglyceride and other fac- tors. The clinical data of two groups were evaluated. Results Among the 133 patients, there were 48 patients suffering from CI. Among 108 patients with TIA in the internal carotid artery system, there were 39 patients suffering from CI. Among 20 patients with TIA in the vertebra-basilar artery system,there were 7 patients suffering from CI. Among 5 patients with TIA in the two systems, there were 2 patients suffering from CI. There was not significantly different in two artery systems （ P 〉 0.05）. The TIA patients with high blood pressure,hyperglycemia and hyperlipoidemia often occurred to CI （ all P 〈 0.05 ）. Conclusion There was high danger for patients to develop CI if patients with TIA lasted for a long time,or treatment was not yet in time, especially those accompanied with high blood pressrre, hyperglycaemia and hyperlipoidemia.

关 键 词：短暂性脑缺血发作 脑梗死 危险因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]