满山红油GC特征图谱的建立及其特征共有峰的GC-MS研究  

Establishment of Oleun Rhododendri Daurici's Characteristics Spectrum and Research on it's Characteristics Peaks by GC-MS

作　　者：李玥瑛 郭丽娟 冯丹 曹飞 仲昭庆 张清波 

机构地区：[1]黑龙江省食品药品检验检测所,哈尔滨150001 [2]山东齐都药业有限公司,淄博255400

出　　处：《中国药品标准》2012年第1期25-29,共5页Drug Standards of China

摘　　要：目的:建立满山红油的特征图谱。方法:采用GC法Agilent HP-5(30 m×0.25 mm×0.25μm)色谱柱,氢火焰离子化检测器(FID),程序升温条件为100℃保持18 min,每分钟0.5℃升温至110℃,再以每分钟1℃升温至140℃,保持20 min,进样量为1μL。结果:经程序升温对满山红油中的50余个成分进行了分离,其中8个峰基本达到基线分离,经GC-MS推测了结构。结论:通过满山红油特征图谱的建立,可以更好的控制满山红油产品的质量。Objective：To establish the characteristic spectrum of 01eun rhododendri daurici. Method： The content was determined by GC with Agilent HP-5 （30 m × 0. 25 mm × 0.25 μm） chromatographic column, with hydrogen flame ionization detector （FID） as detector. First,the temperature should be maintained to 100 ℃ for 18 minutes, and then heating up to 110 ℃ with the speed ofO. 5 ℃ · min-1 ; then heating up to 140 ℃ with the speed of 1 ℃. min-1 , maintain this temperature for 20 minutes. The injection volume was 1 ILL. Results： After programmed temperature processing, more than 50 constituents of Oleun rhododendri daurici were separated and in which 8 peaks achieve baseline separation basically. Conclusion ： For quality control, the characteristic spectrum of oleun rhododendri daurici should be established.

关 键 词：气相色谱-质谱联用 满山红油 特征图谱 

分 类 号：R921.2[医药卫生—药学]