PET/CT对鼻咽癌颅底颅内侵犯的诊断价值及T分期影响  

Diagnostic Value of PET/CT in Nasopharyngeal Carcinoma with Skull Base and Intracranial Involvement and Its Impact on T Staging

作　　者：林少雄[1] 李湘平[1] 刘雄[1] 梁碧君[1] 鲁娟[1] 吴湖炳[1] 

机构地区：[1]南方医科大学南方医院,广东广州510515

出　　处：《肿瘤学杂志》2012年第1期2-5,共4页Journal of Chinese Oncology

基　　金：广东省自然科学基金资助项目(9151051501000093)

摘　　要：[目的]对比PET/CT与MRI诊断鼻咽癌颅底、颅内侵犯的效能,评估PET/CT对以MRI为基础的鼻咽癌T分期影响。[方法]2005年1月至2009年12月,60例患者均行PET/CT和MRI检查,对比PET/CT和MRI的诊断效能及T分期结果。[结果]PET/CT和MRI对鼻咽癌颅底侵犯的敏感性、特异性、准确率分别为96.7%、60.0%和78.3%;76.7%、93.3%和85.0%。PET/CT使28.3%病例T分期提高,8.3%病例T分期下降。[结论]虽然PET/CT对鼻咽癌原发灶侵犯范围的评估效能与MRI相仿,但如以PET/CT作为鼻咽癌分期基础,可能使T分期提高,临床需予以重视。[ Purpose ] To compare the efficacy of PET/CT with MRI for detecting nasopharyngeal carcinoma （NPC） with skull base and intraeranial involvement,and analysis the influence of PET/ CT on MRI based T staging. [Methods] From Jan. 2005 to Dec. 2009,60 cases with NPC were examined with both PET/CT and MRI prior to radiation therapy,the efficacy of each and PET/CT and MRI based T staging were compared. [Results] The sensitivity,specificity and accuracy in detecting skull base involvement were 96.7%,60.0%, 78.3% in PET/CT and 76.7%,93.3%, 85.0% in MRI respectively. PET/CT caused 28.3% of up staging and 8.3% of down staging.[Conclusion] PET/CT raise T staging of NPC based on MRI,though it is not statistically superior to MRI in e- valuating the extent of primary lesion, so.it is worthy of snecial attention in clinic work.

关 键 词：PET/CT 鼻咽肿瘤 颅底 颅内 T分期 

分 类 号：R739.63[医药卫生—肿瘤]