Application of microarray technology in Drosophila ethanol behavioral research  

作　　者：Awoyemi A. AWOFALA 

机构地区：[1]School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom [2]Department of Biological Sciences, Tai Solarin University of Education, Ijebu-Ode, Ogun State, Nigeria

出　　处：《Frontiers in Biology》2012年第1期65-72,共8页生物学前沿（英文版）

摘　　要：Gene expression profiling of Drosophila melanogaster, an invertebrate model organism, applied to DNAmicroarray promises to provide novel insights into the important pathways and molecules that may contribute to the risk of alcohol abuse and addiction. Instead of studying one gene at a time, the technology provides a snapshot of transcriptional changes at once, and offers unprecedented opportunities to understand the molecular complexity of alcohol-seeking behavior including addiction and dependence.Gene expression profiling of Drosophila melanogaster, an invertebrate model organism, applied to DNAmicroarray promises to provide novel insights into the important pathways and molecules that may contribute to the risk of alcohol abuse and addiction. Instead of studying one gene at a time, the technology provides a snapshot of transcriptional changes at once, and offers unprecedented opportunities to understand the molecular complexity of alcohol-seeking behavior including addiction and dependence.

关 键 词：DROSOPHILA BEHAVIOR MICROARRAY gene expression ETHANOL ADDICTION 

分 类 号：Q78[生物学—分子生物学] Q969.462.2