基于中医理论的恶性肿瘤生活质量评价体系之共性量表的研制:测量学特性评价  

Development of the General Module of Quality of Life Assessment System for Cancer Based on Traditional Chinese Medicine:Psychometric Properties

作　　者：万崇华[1] 郑培永[2] 花永强[2] 尤圣富[2] 杨铮[3] 陆金根[2] 宋毅[2] 柳涛[2] 

机构地区：[1]广东医学院人文与管理学院,广东省东莞市523808 [2]上海中医药大学附属龙华医院,上海市200032 [3]广东医学院公共卫生学院

出　　处：《中国全科医学》2012年第4期390-393,共4页Chinese General Practice

基　　金：国家重点基础研究发展计划("973"计划2006CB504604);广东省高等学校人才引进专项资金项目(GK1003)

摘　　要：目的分析评价基于中医理论的恶性肿瘤生活质量评价体系之共性量表(QLASTCM-GM)的测量学特性(信度、效度与反应度)。方法通过240例肺癌和240例胃癌患者纵向的生命质量测定对QLASTCM-GM的测量学特性进行评价。结果各领域及总量表的重测信度均在0.93以上,内部一致性α值为0.86～0.93;相关分析与因子分析显示量表有较好的结构效度;与癌症患者生活质量测定量表(QLQ-C30)的相关分析显示具有较好的效标关联效度;治疗后各领域及总量表得分间差异均有统计学意义(P<0.05),且标准化反应均数(SRM)较QLQ-C30大。结论 QLASTCM-GM具有较好的信度、效度及一定的反应度,可用于癌症患者生命质量的测定。Objective To evaluate psychometric properties （reliability, validity, and responsiveness） of the general module of the quality of life assessment system for cancer based on Traditional Chinese Medicine （ QLASTCM - GM） . Methods QLASTCM - GM was evaluated by quality of life （QOL） data measured from a longitudinal study of 240 patients of lung cancer and 240 patients of gastric cancer. Results The test - retest reliabilities for all domains and the overall scale were above O. 93, thectvalue of internal consistency for all domains were fromO. 86 to 0. 93. Correlation analysis and factor analysis displayed a good construct validity; Criterion -related validity was confirmed by correlation analysis with cancer＇s 30 -item quality of life questionnaire （ QLQ - C30） ; Statistically significant changes （ P 〈0. 05 ） after treatment were found for each domain （ P 〈0. 05 ） and the overall scale, and the standardized response mean （SRM） was greater than that of QLQ - C30. Conclusion The QLASTCM - GM can be used to measure QOL for patients of cancer with good validity and reliability, and. reasonable responsiveness.

关 键 词：肿瘤 生命质量 信度 效度 反应度 

分 类 号：R730.1[医药卫生—肿瘤]