子宫肉瘤23例临床分析  

Clinical analysis of 23 uterine sarcoma

作　　者：许德明[1] 赵小琼[1] 陈焕伟[1] 王博[1] 凌华海[1] 李声谊[1] 林坚[1] 

机构地区：[1]广东省农垦中心医院,广东湛江524002

出　　处：《中国肿瘤临床与康复》2011年第5期449-450,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨子宫肉瘤的诊断及治疗方法。方法回顾性分析1990年1月至2009年12月收治的23例子宫肉瘤患者的临床资料。结果临床表现为不规则阴道流血14例,下腹包块9例,无症状的子宫肌瘤病史4例,腹痛2例。19例行手术,4例子宫肌瘤术后诊断为子宫肉瘤,其中2例做二次手术,1例拒绝二次手术,1例待2年后复发二次手术。术后化学治疗11例,联合化疗方案2～4个疗程。2年存活率51%,5年存活率26%。结论子宫肉瘤临床表现缺乏特异性,主要为不规则阴道流血,怀疑子宫肉瘤或诊断为子宫肌瘤者,应立即做冰冻病理切片检查,以便及时发现子宫肉瘤,以决定手术范围,尽可能减少第二次手术。Objective To explore the diagnosis of uterine sarcoma and treatment.Methods A retrospective analysis in January 1990-2009 admitted on Dec.23 cases of uterine sarcoma in patients with clinical data.Results The clinical manifestations in these 23 casese,14 cases of irregular vaginal bleeding,9 cases of abdominal mass,4 cases of asymptomatic uterine fibroids history,2 cases of abdominal pain.19 routine surgery,4 patients diagnosed with uterine fibroids uterine sarcoma,in which 2 cases did the second surgery,1 patient refused the second operation,1 case of recurrence until 2 years after the second surgery.11 patients after chemotherapy,combined chemotherapy 2 to 4 courses.2-year survival rate were 51%,5-year survival rate were 26%.Conclusion There are no specific clinical manifestations in uterine sarcoma,but mainly express irregular vaginal bleeding;if suspected or diagnosed uterine sarcoma uterine fibroids,should immediately be frozen biopsy in order to detect uterine sarcoma,to determine the extent of surgery to minimize second operation.

关 键 词：子宫肉瘤 子宫平滑肌肉瘤 子宫内膜间质肉瘤 子宫恶性中胚叶混合瘤或癌肉瘤 

分 类 号：R737.33[医药卫生—肿瘤] R730.4[医药卫生—临床医学]