CA125、CA72-4、CA19-9在子宫内膜癌诊断中的评价  

Evaluation of CA125,CA72-4,CA19-9 in the diagnosis of endometrial cancer

作　　者：刘国振[1] 罗兵[2] 台德军[3] 

机构地区：[1]安徽医科大学附属六安医院核医学科,安徽六安237005 [2]安徽医科大学第一附属医院普外科 [3]安徽医科大学第一附属医院检验科,安徽合肥230022

出　　处：《安徽医药》2012年第2期200-202,共3页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨CA125、CA72-4、CA19-9及联合检测在子宫内膜癌诊断中的价值。方法采用电化学发光方法检测血清CA125、CA72-4、CA19-9。结果子宫内膜癌组CA125、CA72-4,炎症反应组CA125阳性率显著高于正常对照(P<0.05);子宫内膜癌CA125的阳性率显著高于炎症反应和平滑肌瘤(P<0.05);CA125的ROC曲线下面积显著高于CA72-4、CA19-9(P<0.05),CA72-4与CA19-9的ROC曲线下面积差别无显著性(P>0.05)。结论 CA125对子宫内膜癌的诊断优于CA72-4和CA19-9,联合检测有助于子宫内膜癌的诊断。Objective To evaluate the value of CA125,CA72-4,CA19-9 and the combined detection in diagnosis of endometrial cancer.Methods Electrochemil-uminescence assay of Roche group was employed to detect serum CA125,CA72-4,CA19-9.Results Positive rates of CA125,CA72-4 in patient with endometrial cancer,CA125 in patient with inflammatory reaction were significantly higher than those in health control（P 0.05） and positive rates of CA125 in patient with endometrial cancer was significantly higher than those in patient with leiomyoma and inflammatory reaction（P 0.05）.The area under curve of CA125 was significant by higher than those of CA72-4 and CA19-9（P 0.05） and there was no significant difference between CA72-4 and CA19-9（P 0.05）.Conclusion CA125 is more useful than CA72-4 and CA19-9 in the diagnosis of endometrial cancer.The combined detection is useful in the diagnosis of endometrial cancer.

关 键 词：CA125 CA72-4 CA19-9 子宫内膜癌 联合检测 

分 类 号：R737.33[医药卫生—肿瘤]