眼干燥综合征相关因素分析及临床干预的效果  

Analysis of the dry eye syndrome-related factors and outcomes of clinical intervention

作　　者：张莉莉[1] 周莉[1] 徐唐[1] 周群[1] 

机构地区：[1]南京大学医学院附属鼓楼医院宁益眼科中心,江苏省210008

出　　处：《江苏医药》2012年第5期574-576,共3页Jiangsu Medical Journal

基　　金：南京市卫生局医学科技发展基金(YKK09106)

摘　　要：目的探讨眼干燥综合征(干眼症)的相关因素和临床干预效果。方法干眼症患者218例,随机均分为干预组(A组,常规给予病因治疗、泪液治疗及系统的临床干预)和对照组(B组,仅常规给予病因治疗和泪液治疗),比较两组治疗2周后的泪液功能试验(SIT)、泪膜破裂时间(TBUT)、角膜荧光染色检查(FL)和自我测评等指标。结果视频终端综合征或看书为干眼症相关的主要因素,占45.41%(99/218),其次分别为闭经或泪腺萎缩老化占37.16%(81/218),眼表手术或用药占33.49%(73/218),户外工作或户外运动者占29.36%(64/218),佩戴隐形眼镜占21.56%(47/218),饮食结构(维生素A缺乏)占7.34%(16/218)。A组SIT、TBUT、FL和自我测评评分均明显高于B组﹙P<0.05﹚。结论干眼症的相关因素是多方面的,科学、有效的实施临床干预能减轻干眼症患者的症状。Objective To investigate the dry eye-related factors and the outcomes of clinical intervention.Methods A total of 218 patients with dry eye was randomly divided into two groups of A（given clinical interventions of etiological treatment,tear treatment and the system clinical intervention） and B（treated with etiological treatment and tear treatment only as the control）.After treated for two weeks,the Schirmer I test（SIT）,tear film break-up time（TBUT）,fluorescin staining of cornea（FL） and self-assessment scores were compared between two groups.Results Of the factors related to dry eye syndrome,Vidio end syndrome or reading acounted for 45.41%（99/218）,menisschesis and lacrimal atrophy for 37.16%（81/218）,surgery or drug administration on the eye surface for 33.49%（73/218）,outdoor working or exercise for 29.36%（64/218）,contact glasses wearing for 21.56%（47/218）,lack of vitamine A for 7.34%（16/218）.The SIT,TBUT,FL and self-assessment scores were all significantly higher in group A than those in group B﹙P0.05﹚.Conclusion The factors related to dry eye syndrome are multiple.The reasonable and effective clinical interventions can reduce the symptoms in the patients with dry eye syndrome.

关 键 词：眼干燥综合征 

分 类 号：R771[医药卫生—眼科]