血管侵犯与结肠癌术后三年预后的关系  

Correlation analysis of venous invasion and 3-year survival of colon cancer patients after surgery

作　　者：李雪[1] 杨小玲[1] 胡秋兰[1] 黄明君[2] 汪晓东[2] 李卡[2] 

机构地区：[1]四川大学华西临床医学院,成都610041 [2]四川大学华西医院胃肠外科中心

出　　处：《临床外科杂志》2012年第2期99-101,共3页Journal of Clinical Surgery

摘　　要：目的 探讨血管侵犯与结肠癌术后3年预后的关系.方法 回顾性分析2006年1月至2007年12月135例我院行手术治疗结肠癌患者的临床和随访资料,按有无血管侵犯分为A组（无血管侵犯）和B组（有血管侵犯）.以患者术后3年生存率、局部复发率、远处转移率和死亡率为观察指标,分析两者的关系.结果 A、B两组术后3年生存期指标中：生存率A组高于B组,差异有统计学意义（83.5%与39.1%,P=0.000）;局部复发率两组差异无统计学意义（6.42%与3.85%,P=1.000）;远处转移率B组高于A组,差异有统计学意义（11.01%与50.00%,P=0.000）;死亡率B组高于A组,差异有统计学意义（14.68%与57.69%,P=0.000）.结论 血管侵犯可作为结肠癌的不良预后因素,伴血管侵犯者术后生存状况明显较无血管侵犯者差.Objective To discuss the impact of venous invasion （VI）on -year survival of colon cancer patients after surgery. Methods Clinical and follow-up data of 135 colon cancer patients underwent surgery in West China hospital from January 2006 to December 2007 were analyzed retrospectively. According to the condition of VI, the patients were divided into group A （without VI, 109 cases）and group B（with VI,26 cases）. We analyzed their relationship by comparing the indicators of 3-year survival after surgery：survival rate, local recurrence rate, tumor metastasis rate and mortality. Results Comparing the indicators of the 3-year survival after surgery of two groups, survival rate of group A（ 83.5% ） was higher than group B （39.1% ）, and the difference was statistically significant （P = 0. 000） ;The difference of local recurrence rate was not statistically significant（6.42% vs. 3.85% , P = 1. 000 ） ;The difference of metastasis rate between group A （ 11.01% ） and group B （ 50.00% ） was statistically significant （ P = 0. 000 ） ; And group A（ 14.68% ）got lower than group B（57.69% ）in mortality,the difference being statistically significant （P = 0. 000）. Conclusion VI by tumor can be an important prognostic factor of colon cancer patients after surgery, and the condition of 3 -year survival in patients with VI is worse than without VI.

关 键 词：结肠癌 血管侵犯 生存期 

分 类 号：R735.35[医药卫生—肿瘤]