青年直肠癌46例外科诊治分析  

Diagnosis and Surgical Treatment of Rectal Cancer in 46 Young Patients

作　　者：郑毅锋[1] 顾觉炜 魏德强[1] 

机构地区：[1]福建省建瓯市立医院外二科,福建建瓯353100

出　　处：《中外医疗》2012年第3期31-32,共2页China & Foreign Medical Treatment

摘　　要：目的探讨青年直肠癌的临床、病理特点和外科诊治体会。方法回顾性分析2001年6至2011年6月10年间收治的46例青年直肠癌患者的病例资料,与同期218例中老年直肠癌患者进行对比分析。结果青年直肠癌误诊率为56.52%,黏液腺癌、低分化腺癌和印戒细胞癌所占比例为47.83%,Ducks C和D期患者比例为73.91%,上述指标均高于中老年直肠癌患者(P<0.05)。青年直肠癌患者5年生存率为70.60%,与中老年直肠患者相当(P>0.05)。结论青年直肠癌容易误诊,肿瘤组织学类型和分化程度较差,确诊时病理分期较晚,通过合理的外科诊治,其远期生存率可以与中老年直肠癌相当。另外,建立多学科协作团队(MDT),强调包括新辅助放化疗在内的综合治疗,外科手术应在根治肿瘤的前提下注意保留功能。Objective To evaluate the clinical and pathologic characteristics and sum up the experience in surgical treatment for young patients with rectal cancer.Methods The datas of 46 rectal cancers which occurred in patients aged 40 years or younger were compared with 218 rectal cancers in older patients（40 years older） treated from Jun.2001 to Jun.2011.Results The misdiagnosis rate of young group was 56.52%.Poorly differentiated tumor grade was more common in young patients as well as mucous adenocarcinoma.Advanced tumor stage（Ducks C and Ducks D） was noted in 73.91% of the young.Survival were similar for the two groups（P〉0.05）.Conclusion Rectal cancer in young patients has poorer histologic differentiation and more advanced pathologic stage,but the long-term survival is similar to that in middle-aged and eldedy patients.On the premise of trying to perform radical resection and adjunctive radiochemotherapy,function-Preserving should be seriously considered.

关 键 词：直肠癌 青年 外科 

分 类 号：R735.3[医药卫生—肿瘤]