中西医结合治疗肠易激综合征的临床观察  

Clinical Efficacy of Treating Irritable Bowel Syndrome with Combination of Traditional Chinese and Western Medicine

作　　者：周慧芬[1] 徐安妗 廖勇仙 

机构地区：[1]江山市中医院,浙江江山324100

出　　处：《中华中医药学刊》2012年第3期652-654,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:中西医结合治疗肠易激综合征,以西药得舒特为对照,从肠道症状和生活质量两方面观察其临床疗效。方法:符合罗马Ⅲ诊断标准的69例肠易激综合征患者,中药1组(以腹泻为主)29例,在西药治疗的基础上加用用疏肝理气,健脾化湿方药治疗,中药2组(以便秘为主)21例,在西药治疗的基础上加用疏肝理气,润肠通便方药治疗,西药对照组18例,予得舒特治疗。3组服药疗程为4周。采用症状等级评分表和SF-36生活质量评价作为判定依据,观察治疗前后各组患者肠道症状及生活质量的变化。结果:①中药1组和中药2组的治疗有效率明显优于对照组,差异有显著性(P<0.05)。②治疗前后中药1组和中药2组患者肠道症状均有显著改善,对照组的腹胀症状无明显改善。中药1组和中药2组对腹痛、大便次数、大便急迫方面的改善作用明显优于对照组。③中药1组和中药2组治疗前后患者躯体疼痛(BP)、总体健康(GH)、活力(VT)、社会功能(SF)、精神健康(MH)维度的积分均有明显提高,具有统计学意义(P<0.05),对照组患者仅活力维度的生活质量得到显著改善,具有统计学差异(P<0.05)。结论:中西医结合治疗肠易激综合征疗效确切,在肠道症状的改善和生活质量的提高两方面都显著优于单一西药治疗组,值得进一步推广。Objective：To observe the clinical efficacy of a combined method including traditional Chinese and western medicine for treating irritable bowel syndrome（IBS）. Methods：IBS was diagnosed based on Rome III standard, sixty - eight IBS patients were randomly divided into three groups, all the patients took oral administration. 29 patients were in the first group, symptoms were mainly diarrhea, treated with Shuganliqi and Jianshihuapi methods; 21 patients in the sec- ond group, symptoms were mainly constipation, treated with Shuganliqi and Runchangtongbian methods; Pinaverium bromide were given in both groups as auxiliary oral medicine; 18 patients in the third group as control group were only given pinaverium bromide. The treating procedure was 4 weeks in all three groups. Symptom grading chart and SF - 36 living quality were used as judgemental basis. Improvement of bowel＇ s syndrome and living quality in three groups were observed pre - and post - treating. Results ： （1）Treating effect was obviously better in the first and second group than the third group, a significant difference was obvious （P 〈 0.05）. （2）Bowel＇ s symptoms were improved in both Chinese traditional medicine treating groups, while it was not obvious in control group, traditional Chinese medicine also reduced the stomachache degree, defecate times and shit urgent symptom in treating groups, while these above symptoms did not change obviously in control group. （3）Bodily pain（ BP）, general health（ GH）, vitality（ VT）, social functioning （SF）and mental health （MH） dimension of integral were significantly improved in treating groups, compared with treating groups, only VT was improved significantly in control group, there were statistical differences （P 〈 0. 05 ）. Conclusion：There are definite effect on treating IBS with combining traditional Chinese and western medicine than single western medicine with obvious improvement in aspects associated with bowel＇s symptom and living quality. It is w

关 键 词：健脾化湿 润肠通便 肠易激综合征 

分 类 号：R574[医药卫生—消化系统]