Impact of androgen deprivation therapy on sexua function  

作　　者：Clarisse R Mazzola John P Mulhall 

机构地区：[1]Sexual and Reproductive Medicine Program,Urology Service,Memorial SIoan Kettering Cancer Center,New York,NY 10065,USA

出　　处：《Asian Journal of Andrology》2012年第2期198-203,共6页亚洲男性学杂志（英文版）

摘　　要：Many patients with prostate cancer for whom androgen deprivation therapy （ADT） is indicated are young and desire to remain sexually active. In such patients, the side effects of androgen therapy on sexual function can be a source of serious reduction in overall quality of life. Providing the appropriate treatment options in this patient population is therefore essential. Nevertheless, treating such patients is challenging and an understanding of the underlying mechanisms of sexual physiology and pathophysiology is crucial to optimal patient care. In this paper, we reviewed what was known regarding the effects of ADT on sexual function in animal models and we also provided a detailed review on the effects of ADT on sexual health in humans and its treatment.Many patients with prostate cancer for whom androgen deprivation therapy （ADT） is indicated are young and desire to remain sexually active. In such patients, the side effects of androgen therapy on sexual function can be a source of serious reduction in overall quality of life. Providing the appropriate treatment options in this patient population is therefore essential. Nevertheless, treating such patients is challenging and an understanding of the underlying mechanisms of sexual physiology and pathophysiology is crucial to optimal patient care. In this paper, we reviewed what was known regarding the effects of ADT on sexual function in animal models and we also provided a detailed review on the effects of ADT on sexual health in humans and its treatment.

关 键 词：androgen deprivation therapy CASTRATION EJACULATION erectile dysfunction ORGASM 

分 类 号：S858.237.2[农业科学—临床兽医学] Q579.11[农业科学—兽医学]