CASTRATION

作品数：43被引量：144H指数：7
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相关作者：屠曾宏钱立晖王晓麟孙国锋王义更多>>
相关机构：中国科学院上海生命科学研究院北京大学首钢医院北京大学四川农业大学更多>>
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Prevalence and risk evaluation of cardiovascular disease in the newly diagnosed prostate cancer population in China:A nationwide,multi-center,population-based cross-sectional study被引量：2
《Chinese Medical Journal》2024年第11期1324-1331,共8页Weiyu Zhang Huixin Liu Ming Liu Shi Ying Renbin Yuan Hao Zeng Zhenting Zhang Sujun Han Zhannan Si Bin Hu Simeng Wen Pengcheng Xu Weimin Yu Hui Chen Liang Wang Zhitao Lin Tao Dai Yunzhi Lin Tao Xu 
National Natural Science Foundation of China(No.82071777);China Urological Cancer Research Foundation from Beijing Life Oasis Public Service Center(No.2023-Z-16)
Background:Cardiovascular disease(CVD)has emerged as the leading cause of death from prostate cancer(PCa)in recent decades,bringing a great disease burden worldwide.Men with preexisting CVD have an increased risk for ...
关键词：Prostate cancer CASTRATION Cardiovascular disease PREVALENCE Cardiovascular risk 
Effect of Menopausal Hormone Replacement Therapy on Cytokine Patterns in a Perimenopausal Mouse Model Established by the Ovarian Castration Method
《Chinese Journal of Biomedical Engineering(English Edition)》2024年第1期40-48,共9页HE Bin-bin ZHANG Ju-shun WANG Jin-yong 
Objective: To investigate the effect of perimenopausal hormone replacement therapy(HRT) on cytokine patterns in a perimenopausal mouse model established by ovarian castration. Methods: The mice were divided into natur...
关键词：MENOPAUSE hormone replacement therapy(HRT) OVARIECTOMY mouse model cytokine pattern 
Analysis of risk factors leading to anxiety and depression in patients with prostate cancer after castration and the construction of a risk prediction model被引量：3
《World Journal of Psychiatry》2024年第2期255-265,共11页Rui-Xiao Li Xue-Lian Li Guo-Jun Wu Yong-Hua Lei Xiao-Shun Li Bo Li Jian-Xin Ni 
BACKGROUND Cancer patients often suffer from severe stress reactions psychologically,such as anxiety and depression.Prostate cancer(PC)is one of the common cancer types,with most patients diagnosed at advanced stages ...
关键词：Prostate cancer CASTRATION Anxiety and depression Risk factors Risk prediction model 
Apalutamide for metastatic castration-sensitive prostate cancer:final analysis of the Asian subpopulation in the TITAN trial
《Asian Journal of Andrology》2023年第6期653-661,共9页Byung Ha Chung Jian Huang Hiroji Uemura Young Deuk Choi Zhang-Qun Ye Hiroyoshi Suzuki Taek Won Kang Da-Lin He Jae Young Joung Sabine D Brookman-May Sharon McCarthy Amitabha Bhaumik Anildeep Singh Suneel Mundle Simon Chowdhury Neeraj Agarwal Ding-Wei Ye Kim N Chi Hirotsugu Uemura 
The study was funded by Janssen Pharmaceutical Ltd.Writing assistance was provided by Katherine A Lyseng-Williamson and Kerry Dechant,ISMPP CMPP^(TM),on behalf of Content Ed Net,and was funded by Janssen Pharmaceutical Ltd.Janssen Pharmaceutical Ltd.is not involved in the process of experimental design,results,or discussion,and has no competing interests with this study.
The final analysis of the phase 3 Targeted Investigational Treatment Analysis of Novel Anti-androgen(TITAN)trial showed improvement in overall survival(OS)and other efficacy endpoints with apalutamide plus androgen de...
关键词：apalutamide Asia event-driven analysis metastatic castration-sensitive prostate cancer overall survival 
Urological and genital surgery in ancient Egypt
《History & Philosophy of Medicine》2023年第1期16-23,共8页Patric Blomstedt 
Background:Ancient Egypt might be considered the cradle of medicine.The modern literature is somewhat too enthusiastic regarding the procedures given an Egyptian origin.The aim of the current paper is to briefly analy...
关键词：EGYPT UROLOGY CIRCUMCISION CASTRATION HISTORY 
IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation
《Cancer Biology & Medicine》2022年第7期1008-1028,共21页Tingting Feng Jing Wang Kai Cheng Qiqi Lu Ru Zhao Shiguan Wang Qingyun Zhang Luna Ge Jihong Pan Guanhua Song Lin Wang 
supported by the National Natural Science Foundation of China(Grant Nos.81772760 and 82072850);the Natural Science Foundation of Shandong Province(Grant Nos.ZR2020YQ55 and ZR2020QH327),the Shandong Taishan Scholarship(Grant No.tsqn20161076);the Innovation Project of Shandong Academy of Medical Sciences(2020);the program for Outstanding PhD candidate of Shandong University(2020)and Academic promotion programme of Shandong First Medical University(LJ001).
Objective:Androgen deprivation therapy(ADT)is still the principal treatment option for prostate cancer(PCa).In addition to reactivation of androgen receptor signaling,the resistance of PCa to apoptosis during ADT also...
关键词：Prostate cancer castration resistance IL13Rα1 apoptosis GLYCOLYSIS 
Real-world evaluation of upfront docetaxel in metastatic castrationsensitive prostate cancer
《World Journal of Clinical Oncology》2021年第11期1009-1022,共14页Jenny Isaksson Henrik Green Dimitrios Papantoniou Linn Pettersson Mats Anden Johan Rosell Elisabeth Åvall-Lundqvist Nils Oskar Elander 
the Declaration of Helsinki and was approved by the Regional Ethics Review board in Linköping,RegionÖstergötland,Sweden,No.2018/139–31.
BACKGROUND The majority of patients with newly diagnosed metastatic prostate cancer(PC)initially respond to androgen deprivation therapy(ADT)and are classified as metastatic castration-sensitive PC(mCSPC).Following mo...
关键词：Prostate cancer CHEMOTHERAPY DOCETAXEL Castration sensitive METASTATIC Real world 
How do we define “castration” in men on androgen deprivation therapy?
《Asian Journal of Andrology》2020年第5期441-446,共6页Sarin Itty Robert H Getzenberg 
Androgen deprivation therapy(ADT)is the mainstay for the treatment of advanced prostate cancer.Since the clinical evolution from surgical orchiectomy,we have typically used ADT and orchiectomy to be synonymous terms f...
关键词：ANDROGEN androgen deprivation therapy CASTRATION free testosterone TESTOSTERONE 
Prognostic significance of castrate testosterone levels for patients with intermediate and high risk prostate cancer被引量：1
《World Journal of Clinical Oncology》2019年第8期283-292,共10页Gokhan Ozyigit Pervin Hurmuz Deniz Yuce Fadil Akyol 
BACKGROUND Testosterone level of < 50 ng/dL has been used to define castrate level after surgery or after androgen deprivation treatment (ADT) in metastatic prostate cancer (PC). AIM To evaluate the effect of two diff...
关键词：PROSTATE cancer ANDROGEN DEPRIVATION therapy RADIOTHERAPY TESTOSTERONE CASTRATION 
Metastatic(Advanced)Prostate Cancer Resistant to Castration:The Time before Resistance Development and Therapeutic Measures Undertaken in Cote d’Ivoire
《Journal of Cancer Therapy》2018年第12期955-961,共7页Kouassi Kouame Konan Yvon Toure Moctar Seka Evrard Narcisse Oumou Kimso Traore Kadjatou Odo Bitti Adde Traore Asmaho Danielle Kagambega Arsene Gaetan Adoubi Innocent 
Objective: Contribute to improving care for prostate cancer patients in Cote d’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and...
关键词：Cancer PROSTATE Occurrence Time Resistance 
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