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作品数:209被引量:504H指数:11
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相关领域:医药卫生更多>>
相关作者:王忠徐明曦董国勤崔毓桂达骏更多>>
相关机构:上海交通大学医学院附属第九人民医院中国福利会国际和平妇幼保健院兰州大学第二医院齐齐哈尔医学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划上海市自然科学基金国家教育部博士点基金更多>>
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Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration
《Neural Regeneration Research》2025年第9期2581-2582,共2页Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari 
supported by a grant from the French Multiple Sclerosis Society(ARSEP,Grant Number:R20163LL)(to AMG)。
Multiple sclerosis(MS)is the most common chronic disease of the central nervous system(CNS)in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterize...
关键词:MYELIN CXCR4 
Suppression of hepatic steatosis in non-alcoholic steatohepatitis model by modified Xiaoyao San formula:Evidence,mechanisms and perspective
《World Journal of Hepatology》2024年第10期1208-1212,共5页Nabil Eid Payal Bhatnagar Li-Li Chan Marina Garcia-Macia 
In this letter,we comment on a recent publication by Mei et al,in the World Journal of Hepatology,investigating the hepatoprotective effects of the modified Xiaoyao San(MXS)formula in a male rat model of non-alcoholic...
关键词:STEATOSIS Liver Xiaoyao San Inflammation ANDROGEN Adenosine 5’-monophosphate-activated protein kinase Phosphatase and tensin homolog Autophagy Lipophagy Alpha smooth muscle actin 
Korean red ginseng alleviates benign prostatic hyperplasia by dysregulating androgen receptor signaling and inhibiting DRP1-mediated mitochondrial fission被引量:1
《Chinese Journal of Natural Medicines》2024年第7期599-607,共9页HONG Geum-Lan KIM Kyung-Hyun CHO Sung-Pil LEE Hui-Ju KIM Yae-Ji JUNG Ju-Young 
supported by the 2021 Grant from the Korean Society of Ginseng。
Panax ginseng(C.A.Mey.)has been traditionally employed in Korea and China to alleviate fatigue and digestive disorders.In particular,Korean red ginseng(KRG),derived from streamed and dried P.ginseng,is known for its a...
关键词:ANDROGEN Benign prostatic hyperplasia FISSION Korean red ginseng MITOCHONDRIA 
The Pathogenesis and Treatment Progress of Androgenic Alopecia
《Journal of Biosciences and Medicines》2024年第6期149-158,共10页Huijuan Fan Faqing Huang 
Androgenic alopecia, also known as seborrheic alopecia, is the most common hair loss disorder in dermatology clinics, mainly characterized by hair follicle miniaturization and progressive hair loss. The etiology and p...
关键词:Androgen Alopecia PATHOGENESIS Gene Expression Signal Transduction Treatment Progress Targeted Therapy 
Androgen signaling inhibits de novo lipogenesis to alleviate lipid deposition in zebrafish被引量:1
《Zoological Research》2024年第2期355-366,共12页Jing-Yi Jia Guang-Hui Chen Ting-Ting Shu Qi-Yong Lou Xia Jin Jiang-Yan He Wu-Han Xiao Gang Zhai Zhan Yin 
supported by the National Key Research and Development Program,China (2022YFF1000300 to Z.Y.and2022YFD2401800 to G.Z.);Pilot Program A Project from the Chinese Academy of Sciences (XDA24010206 to Z.Y.);Foundation of Hubei Hongshan Laboratory (2021hskf013 to G.Z.and 2021hszd021 to Z.Y.);National Natural Science Foundation of China (31972779 to G.Z.);Youth Innovation Promotion Association of CAS (2020336 to G.Z.);State Key Laboratory of Freshwater Ecology and Biotechnology (2016FBZ05 to Z.Y.)。
Testosterone is closely associated with lipid metabolism and known to affect body fat composition and muscle mass in males.However,the mechanisms by which testosterone acts on lipid metabolism are not yet fully unders...
关键词:Cyp17a1 TESTOSTERONE Androgen receptor De novo lipogenesis Fatty acid synthesis 
Defective Expression of the Gap Junction Protein Pannexin-1 Channel Contributes to the Formation of PCOS-Realted Androgenetic Alopecia
《Advances in Reproductive Sciences》2023年第4期86-92,共7页Sule Gencoglu Fatma Tanilir Cagiran Zercan Kali 
Objective: To determine serum pannexin-1 channel levels and their association with hair loss in women with PCOS diagnosed with female androgenetic alopecia (FAGA). Materials and Methods: Thirty-five women with PCOS wh...
关键词:Androgenetic Alopecia PCOS ANDROGEN Pannexin-1 Channel Inflammation 
Deoxynortryptoquivaline:A unique antiprostate cancer agent
《Oncology Research》2023年第6期845-853,共9页YOHKO YAMAZAKI MANABU KAWADA ISAO MOMOSE 
supported by JSPS KAKENHI Grant Number JP24592417.
The androgen receptor (AR) is a critical target in all the clinical stages of prostate cancer. To identify a new ARinhibitor, we constructed a new screening system using the androgen-dependent growth of prostate cance...
关键词:Anticancer antibiotics Prostate cancer Androgen receptor Androgen dependency 
Association of anti-mullerian hormone and free androgen index level on response to clomiphene citrate in PCOS infertile women被引量:1
《Gynecology and Obstetrics Clinical Medicine》2022年第4期203-207,共5页Jasmine Kavitha Washington Jayasree Manivasakan Poomalar Gunasekaran Kala Sasikala R. 
Background:Polycystic ovary syndrome(PCOS)is the leading cause of anovulatory infertility.Clomiphene citrate,insulin-sensitizing drugs,aromatase inhibitors,gonadotropins,or laparoscopic ovarian drilling are various me...
关键词:Free androgen index anti-Mullerian hormone CLOMIPHENE INFERTILITY Polycystic ovarian syndrome 
Single-cell transcriptome reveals core cell populations and androgen-RXFP2 axis involved in deer antler full regeneration被引量:3
《Cell Regeneration》2022年第1期449-467,共19页Hengxing Ba Xin Wang Datao Wang Jing Ren Zhen Wang Hai-Xi Sun Pengfei Hu Guokun Zhang Shengnan Wang Chao Ma Yusu Wang Enpeng Wang Liang Chen Tianbin Liu Ying Gu Chunyi Li 
This project was supported by National Natural Science Foundation of China(No.U20A20403 and No.31901058);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA16030305);Natural Science Foundation of Jilin Province(YDZJ202201ZYTS690);Jilin Province Education Department Support Program(No.JJKH20221324KJ);Changchun Science and Technology Development Funds(No.21ZY51).
Deer antlers constitute a unique mammalian model for the study of both organ formation in postnatal life and annual full regeneration.Previous studies revealed that these events are achieved through the proliferation ...
关键词:ANTLER THY1+cell Generation REGENERATION Core cell population Androgen-RXFP2 axis Single cell sequencing 
Control of gonadal maturation and sex in grouper被引量:1
《Aquaculture and Fisheries》2022年第5期519-524,共6页Yasuhisa Kobayashi 
JSPS KAKENHI Grant Numbers J18H02281,16K07873,19K06229.I express special thanks to grouper research member(Prof.Masaru Nakamura[Okinawa Churashima Foundation],Dr.Ryo Nozu[Kumamoto Univ.]and Dr.Ryosuke Murata[Nagasaki Univ.])for their kind assistance and useful advice.
Protogynous groupers,belonging to the subfamily Epinephelinae,are among the most crucial fishery targets in the Asian countries.Currently,several grouper species are cultured,providing seed for the aquaculture industr...
关键词:GROUPER Sex change Protogynous Gonadal maturation ANDROGEN ESTROGEN 
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