RADIOTHERAPY

作品数:1127被引量:3260H指数:23
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相关领域:医药卫生更多>>
相关作者:陈福进洪明晃曾宗渊邵宏金风更多>>
相关机构:中山大学中国医学科学院肿瘤医院上海医科大学复旦大学附属肿瘤医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金安徽省自然科学基金更多>>
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Clinical translation of ultra-high dose rate flash radiotherapy:Opportunities,challenges,and prospects
《World Journal of Radiology》2025年第4期1-11,共11页Xiang-Xiang Yang Hui Luo Jia-Jun Zhang Heng Ge Liang Ge 
Ultra-high dose rate flash radiotherapy(FLASH-RT)has attracted wide attention in the field of radiotherapy in recent years.For FLASH-RT,radiation is delivered at a very high dose rate[usually thousands of times compar...
关键词:Ultra-high dose rate flash radiotherapy MECHANISM Clinical translation Radiation-induced damage to normal tissues PROSPECTS 
Modified logistic nanodosimetry model for calculating relative biological effectiveness
《Nuclear Science and Techniques》2025年第4期72-81,共10页Jing-Fen Yang Xin-Guo Liu Hui Zhang Peng-Bo He Yuan-Yuan Ma Guo-Sheng Shen Wei-Qiang Chen Qiang Li 
supported by the National Key Research and Development Program of China(No.2022YFC2401503);Key Research and Development Program of Gansu Province(No.23YFFA0010);Natural Science Foundation of Gansu Province(No.23JRRA625);Special Project of Science and Technology Cooperation between Hubei Province and Chinese Academy of Sciences(No.42000021817T300000050)。
DNA double-strand breaks(DSBs)may result in cellular mutations,apoptosis,and cell death,making them critical determinants of cellular survival and functionality,as well as major mechanisms underlying cell death.The su...
关键词:NANODOSIMETRY DNA double-strand break probability Biophysical model Carbon-ion radiotherapy 
Nano-drug delivery systems integrated with low radiation doses for enhanced therapeutic efficacy in cancer treatment
《World Journal of Clinical Cases》2025年第10期14-27,共14页Antonio Pontoriero Paola Critelli Marco Zeppieri Alberto Bosurgi Stefania Guercio Maria Caffo Filippo Flavio Angileri Silvana Parisi Salvatore Lavalle Stefano Pergolizzi 
BACKGROUND Precision medicine is an emerging field that includes tumor-targeted delivery and tumor microenvironment.This review explores the synergistic potential of combining nano-drug delivery systems with low radia...
关键词:NANOMEDICINE NANOPARTICLES DRUG-DELIVERY RADIOTHERAPY Combination therapy 
Anxiety,depression,and coping styles among cervical cancer patients during radiotherapy and their correlations with uncertainty in illness
《World Journal of Psychiatry》2025年第4期141-148,共8页Chen-Ying Ma Jing Shang Lu Zhang Jie Chen Ke-Yan Qian Ju-Ying Zhou 
Supported by National Natural Science Foundation of China,No.81602792;The Natural Science Foundation of the Jiangsu Higher Education Institutions of China,No.23KJB310023;Jiangsu Provincial Medical Key Discipline,No.ZDXK202235;The Maternal and Child Health Research Project of Jiangsu Province,No.F202210;The Project of State Key Laboratory of Radiation Medicine and Protection,Soochow University,No.GZK1202101;Suzhou Science and Technology Development Plan Project,No.KJXW2020008;BOXI Natural Science Cultivation Foundation of China of The First Affiliated Hospital of Soochow University,No.BXQN202107;Clinical Diagnosis and Treatment Technology Innovation Project Youth Characteristic Technology Project of The First Affiliated Hospital of Soochow University,No.2100201.
BACKGROUND Currently,there is limited research examining the relationship between anxiety,depression,coping styles,and illness uncertainty in patients with cervical cancer(CC)undergoing radiotherapy.Addressing this ga...
关键词:Cervical cancer RADIOTHERAPY ANXIETY DEPRESSION Coping styles Uncertainty in illness 
Advances in radiotherapy in the treatment of esophageal cancer
《World Journal of Clinical Oncology》2025年第3期181-186,共6页Vrushab Rao Soumya Singh Bhooshan Zade 
Recent advancements in radiotherapy for esophageal cancer have significantly improved treatment outcomes and patient quality of life.Traditional radiotherapy techniques have been enhanced by the integration of advance...
关键词:Esophageal cancer RADIOTHERAPY ADVANCES Immunotherapy Multi-modality treatment CHEMORADIOTHERAPY 
Efficacy and safety of radiotherapy in patients with microsatellite stable or proficient mismatch repair colorectal cancer liver metastasis
《World Journal of Gastrointestinal Oncology》2025年第3期59-68,共10页Jie Ni Chu-Gen Wan Zi-Qi Sui 
BACKGROUND Colorectal cancer is one of the malignant tumors with a high incidence and mortality rate globally,and the occurrence of liver metastasis significantly affects patient survival prognosis.In recent years,the...
关键词:Microsatellite stability Proficient mismatch repair Colorectal cancer Liver metastasis RADIOTHERAPY Immune checkpoint inhibitors Tyrosine kinase inhibitor Efficacy Safety 
Nano-Assisted Radiotherapy Strategies:New Opportunities for Treatment of Non-Small Cell Lung Cancer
《Research》2025年第1期782-802,共21页Lihong Zhao Mei Li Chen Shen Yurui Luo Xiaoming Hou Yu Qi Ziwei Huang Wei Li Lanyang Gao Min Wu Yao Luo 
supported by the National Natural Science Foundation of China(82003262);Science and Technology Program of Sichuan Province(2024NSFSC1922);Zigong Academy of Medical Sciences 2022(ZGYKY22KF002);Sichuan University Postdoctoral Interdisciplinary Innovation Fund;Post-Doctor Research Project,West China Hospital,Sichuan University(2021HXBH009).
Lung cancer is the second most commonly diagnosed cancer and a leading cause of cancer-related death,with non-small cell lung cancer(NSCLC)being the most prevalent type.Over 70%of lung cancer patients require radiothe...
关键词:tumor microenvironment direct indirect mechanisms RADIOSENSITIZERS nano assisted radiotherapy healthy tissues non small cell lung cancer radiological resistancemaking enhance its precision 
Therapeutic strategies and prognostic challenges in linitis plastica
《World Journal of Experimental Medicine》2025年第1期1-5,共5页Grigorios Christodoulidis Sara Eirini Agko Konstantinos Eleftherios Koumarelas Marina Nektaria Kouliou 
Gastric cancer ranks fifth as the most common cancer and third as the leading cause of death worldwide.Risk factors include advancing age,low-fiber diets,high salt intake and Helicobacter pylori infection.Diagnosis re...
关键词:Linitis plastica SURGERY CHEMOTHERAPY RADIOTHERAPY Treatment strategies Gastric cancer 
Safety and effectiveness of induction chemoimmunotherapy followed by definitive radiotherapy or concurrent chemoradiotherapy in esophageal squamous cell carcinoma
《World Journal of Clinical Oncology》2025年第3期30-39,共10页Zhuo-Jun Wei Lin Wang Rui-Qi Wang Yu Wang Huan Chen Hong-Lian Ma Yu-Jin Xu 
Supported by Natural Science Foundation of Zhejiang Province,China,No.LGF21H160005;Zhejiang Medical and Health Science and Technology Project,China,No.2024KY049.
BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a common malignancy in China,often diagnosed at an advanced stage,with poor prognosis.Standard treatments such as definitive chemoradiotherapy offer limited surviv...
关键词:Esophageal squamous cell carcinoma RADIOTHERAPY Immune checkpoint inhibitors CHEMOTHERAPY Patient safety Treatment outcome 
Identifying adipocyte-derived exosomal miRNAs as potential novel prognostic markers for radiotherapy of esophageal squamous cell carcinoma
《World Journal of Gastrointestinal Oncology》2025年第2期211-229,共19页Yang-Yang Ge Xiao-Chun Xia An-Qing Wu Chen-Ying Ma Ling-Hui Yu Ju-Ying Zhou 
Supported by the National Natural Science Foundation of China,No.81602792 and No.12205215;and Science and Technology Program of Nantong,No.JC12022103.
BACKGROUND Radiation resistance limits radiotherapy efficacy in esophageal squamous cell carcinoma(ESCC).The tumor microenvironment,particularly adipocytes,plays a role in promoting cancer progression.Extracellular ve...
关键词:Esophageal squamous cell carcinoma ADIPOCYTE EXOSOMES MicroRNA RADIOTHERAPY 
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