ADIPOCYTE

作品数：124被引量：347H指数：10
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相关领域：医药卫生生物学更多>>
相关作者：刘贇罗敏左祥生李纪平骆天红更多>>
相关机构：加利福尼亚大学上海交通大学医学院附属瑞金医院大连医科大学附属第二医院南京市妇幼保健院更多>>
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Deficiency of circadian gene Per2 blocks luteolin-induced adipocyte browning in mice through weakening liver PPARα/RXRα/FGF21 pathway
《Food Science and Human Wellness》2025年第3期892-901,共10页Shanshan Shui Juan Chen Yan Lin Jingjing Yuan Xin Wang Xian Zhang Jian Liu Lei Zheng 
During the development of diet-induced obesity,the change of energy matebolism is closely related to the function of the circadian clock in mammals.Luteolin(LU),one of the most common natural flavonoids riched in many...
关键词：Obesity Circadian clock LUTEOLIN Per2 gene Adipose tissue browning 
A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer
《Oncology Research》2025年第5期1199-1215,共17页JIA CHEN FEI JIANG KAIYI NIU HAODONG ZHAO LI LI HONGZHU YU 
funded by the Natural Science Research Project of Anhui Educational Committee(2023AH050650);the Research Fund Program of Anhui Medical University(2023xkj176).
Backgrounds:As cancer progresses through various stages of malignancy,metastasis,and drug resistance,the Wnt/-catenin signaling is frequently dysregulated.Despite advancements in medical technology and therapeutic str...
关键词：Gastric Cancer(GC) Signature genes Prognosis Carboxypeptidase Z(CPZ) Adipocyte Enhancer Binding Protein 1(AEBP1) 
Hydroxy-α-sanshool-loaded adipose-targeted mesoporous silica nanoparticles induce white adipose browning and reduce obesity by activating TRPV1
《Bio-Design and Manufacturing》2025年第2期288-309,I0005-I0011,共29页Qing Zhang Chengxun He Juan Guo Dandan Tang Die Qian Chuan Zheng Chunjie Wu Wei Peng 
supported by the Natural Science Foundation of Sichuan Province(No.2022NSFSC0720);Research Center for the Development of the Comprehensive Health Industry and Rural Revitalization of Sichuan TCM(No.DJKYB202306);State Administration of Traditional Chinese Medicine of Sichuan Province of China(No.2020HJZX001).
Obesity has become a global threat to health;however,the available drugs for treating obesity are limited.We investigated the anti-obesity effect of hydroxy-α-sanshool(HAS),an amide derived from the fruit of Zanthoxy...
关键词：Hydroxy-α-sanshool Adipocyte targetability Mesoporous silica nanoparticles White adipose tissue browning OBESITY 
Protective function of adipocyte-derived extracellular vesicles and adipose stem cells in damage repair and regeneration
《Chinese Journal of Plastic and Reconstructive Surgery》2025年第1期35-44,共10页Yanwen Wang Poh-ching Tan Xuewen Xu Shuangbai Zhou 
supported by the National Natural Science Foundation of China(grant no.82272287).
Adipocyte-secreted extracellular vesicles(EVs)and adipose-derived stem cells(ADSCs)regulate physiological and pathological processes by delivering nucleic acids,proteins,and lipids.Both adipocyte-and ADSC-derived EVs ...
关键词：Extracellular vesicles Adipose-derived stem cell ADIPOCYTE Damage repair Wound healing Myocardial injury 
Identifying adipocyte-derived exosomal miRNAs as potential novel prognostic markers for radiotherapy of esophageal squamous cell carcinoma
《World Journal of Gastrointestinal Oncology》2025年第2期211-229,共19页Yang-Yang Ge Xiao-Chun Xia An-Qing Wu Chen-Ying Ma Ling-Hui Yu Ju-Ying Zhou 
Supported by the National Natural Science Foundation of China,No.81602792 and No.12205215;and Science and Technology Program of Nantong,No.JC12022103.
BACKGROUND Radiation resistance limits radiotherapy efficacy in esophageal squamous cell carcinoma(ESCC).The tumor microenvironment,particularly adipocytes,plays a role in promoting cancer progression.Extracellular ve...
关键词：Esophageal squamous cell carcinoma ADIPOCYTE EXOSOMES MicroRNA RADIOTHERAPY 
GLP-1RAs attenuated obesity and reversed leptin resistance partly via activating the microbiome-derived inosine/A2A pathway
《Acta Pharmaceutica Sinica B》2025年第2期1023-1038,共16页Chunyan Dong Bailing Zhou Binyan Zhao Ke Lin Yaomei Tian Rui Zhang Daoyuan Xie Siwen Wu Li Yang 
supported by the 1.3.5 Project for Disciplines of Excellence(No.ZYGD18007);West China Hospital,Sichuan University,the Natural Science Foundation Project of Sichuan Province(No.2022NSFSC1309,China);the National Natural Science Foundation of China(No.82203016).
Extensive evidence has demonstrated that glucagon-like peptide-1 receptor agonists(GLP-1RAs)can ameliorate obesity.Our previous studies revealed that(Ex-4)2-Fc,a long-acting GLP-1RA we developed,depends on the leptin ...
关键词：OBESITY GLP-1RAs Gut microbiota Metabolite Obesity-related inflammation Leptin resistance Macrophage-adipocyte A2A pathway 
Immortalization of epidural fat-derived mesenchymal stem cells: In vitro characterization and adipocyte differentiation potential
《World Journal of Stem Cells》2025年第1期40-52,共13页Seoung-Woo Lee Young-Ju Lim Hee-Yeon Kim Wansoo Kim Wook-Tae Park Min-Jung Ma Junho Lee Min-Soo Seo Young In Kim Sangbum Park Seong-Kyoon Choi Gun Woo Lee 
BACKGROUND Mesenchymal stem cells(MSCs)are promising candidates for regenerative therapy due to their self-renewal capability,multilineage differentiation potential,and immunomodulatory effects.The molecular character...
关键词：IMMORTALIZATION TRANSFECTION Stem cell Epidural fat Proteomics 
Neonatal vitamin A but not retinoic acid administration increases intramuscular adipocyte number in sheep by promoting vascularization
《Animal Nutrition》2024年第4期215-225,共11页Zhongzuo Huang Xiaoxiao Yu Zongyou Jiang Gaojian Tang Shaoqi Gao Yifan Xiang Yicheng Luo Boping Ye Yating Li Pengkang Song Yu Xin Min Du Junxing Zhao Bo Wang 
supported by grants from the National Natural Science Foundation of China (32272892,31972559);the Key Research and Development Program-Key Projects (2021YFD1200900 and 2023YFD1301302);the Young Talent Supporting Program Funding of the College of Animal Science and Technology,and China Agricultural University Education Foundation Grant(1041-2221002)
This study investigated whether vitamin A(VA)administration during the neonatal stage could increase the number of intramuscular adipocytes in Hu sheep by promoting vascularity.A total of 56 newborn male Hu sheep were...
关键词：SHEEP Vitamin A Retinoic acid Intramuscular fat ADIPOGENESIS Angiogenesis 
Lacticaseibacillus paracasei K56 inhibits lipid accumulation in adipocytes by promoting lipolysis
《Food Science and Human Wellness》2024年第6期3511-3521,共11页Silu Wang Jinxing Li Wei-Hsien Liu Niya Li Huijing Liang Weilian Hung Qiuyue Jiang Ruyue Cheng Xi Shen Fang He 
supported by the Yili Industrial Group Co., Ltd., and National Natural Science Foundation of China (81973042).
Probiotics crosstalk immunity to improve host glycolipid metabolism,which is a new strategy for obesity.This study aimed to explore the functions of Lacticaseibacillus paracasei K56(K56),in regulating the lipid metabo...
关键词：OBESITY Lacticaseibacillus MACROPHAGE ADIPOCYTE LIPOLYSIS 
Spatial transcriptomic analysis deciphers adipocyte-to-fibroblast transformation in bleomycin-induced murine skin fibrosis
《Chinese Medical Journal》2024年第22期2745-2757,共13页Yixiang Zhang Jiahao He Fangzhou Xie Shengzhou Shan Jiaqi Qin Chuandong Wang Qingfeng Li Yun Xie Bin Fang 
supported from grants from the National Natural Science Foundation of China(No.82102327);Clinical Research Program of 9th People’s Hospital,Shanghai JiaoTong University School of Medicine(No.JYLJ202103)。
Background:Scleroderma is characterized by inflammation and fibrosis,predominantly occurring in the skin and extending to various parts of the body.The pathophysiology of scleroderma is multifaceted,with the current u...
关键词：Spatial transcriptome SCLERODERMA ADIPOCYTES Fibroblasts 
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