supported by the National Key R&D Program of China from Ministry of Science&Technology(2020YFA0803800,2019YFA0801900,NSFC92057115);Shanghai Sailing Program 20YF1402600 to H.H.,the National Key R&D Program of China from Ministry of Science&Technology(2020YFA0803600,2018YFA0801300,2023YFA1801000 to J.L.);the National Natural Science Foundation of China(32071138 and 32371193 to J.L.),and SKLGE-2118 to J.L.
Neurotensin(NTS)is a secretory peptide produced by lymphatic endothelial cells.Our previous study revealed that NTS suppressed the activity of brown adipose tissue via interactions with NTSR2.In the current study,we f...
supported by the Yili Industrial Group Co., Ltd., and National Natural Science Foundation of China (81973042).
Probiotics crosstalk immunity to improve host glycolipid metabolism,which is a new strategy for obesity.This study aimed to explore the functions of Lacticaseibacillus paracasei K56(K56),in regulating the lipid metabo...
support of the ITMO Cancer and ITMO Technologies pour la Santécoordinated by AVIESAN(National Alliance for Life Sciences&Health),within the framework of the Cancer Plan(France).
Cancer-associated adipocytes(CAAs)have emerged as pivotal players in various cancers,particularly in such as breast cancer,significantly influencing their progression and therapy resistance.Understanding the adipocyte...
supported by the Basic Science Center Program of National Natural Science Foundation of China(No.T2288102);the Key Program of the National Natural Science Foundation of China(No.32230059);the National Natural Science Foundation of China(No.32301123);the Foundation of Frontiers Science Center for Materiobiology and Dynamic Chemistry(No.JKVD1211002);the Wego Project of Chinese Academy of Sciences[No.(2020)005];the China Postdoctoral Science Foundation(No.2022M721147);the Project of National Facility for Translational Medicine(Shanghai)(No.TMSK-2021-134);the Peak Disciplines(Type IV)of Institutions of Higher Learning in Shanghai.
Hematopoietic stem cell transplantation(HSCT)is extensively employed in the treatment of hematological malignancies but is markedly constrained by the paucity of hematopoietic stem/progenitor cells(HSPCs).Recent studi...
funded by the Michigan Animal Agricultural Alliance competitive project#AA-23–0014;United States Department of Agriculture National Institute of Food and Agriculture(USDA)projects#2019–67015-29443 and#2021–67037-34657;the United States-Israel Binational Agricultural Research Development(BARD)Fund project#IS-5167–19;the Office for the Associate Dean of Research at Michigan State University;supported by USDA National Institute of Food and Agriculture’s Agriculture and Food Research Initiative Educational Workforce and Development Program award#2024-67011-42947。
Background As cows transition from pregnancy to lactation,free fatty acids(FFA)are mobilized from adipose tissues(AT)through lipolysis to counter energy deficits.In clinically healthy cows,lipolysis intensity is reduc...
supported from grants from the National Natural Science Foundation of China(No.82102327);Clinical Research Program of 9th People’s Hospital,Shanghai JiaoTong University School of Medicine(No.JYLJ202103)。
Background:Scleroderma is characterized by inflammation and fibrosis,predominantly occurring in the skin and extending to various parts of the body.The pathophysiology of scleroderma is multifaceted,with the current u...
supported by the National Natural Science Foundation of China (32272847, U22A20516);the Key Research and Development Program of Shaanxi Province (2022ZDLNY01-04);the China Agriculture Research System of MOF and MARA (CARS-35)。
Background Pork quality is affected by the type of muscle fibers, which is closely related to meat color, tenderness and juiciness. Exosomes are tiny vesicles with a diameter of approximately 30–150 nm that are secre...
Supported by National Traditional Chinese Medicine Inheritance and Innovation Platform Construction Project by National Administration of Traditional Chinese Medicine,No.Y2020CX57;Jiangsu Provincial Administration of Traditional Chinese Medicine,No.MS2023014;Jiangsu Graduate Student Research and Practice Innovation Program,No.SJCX23_0799。
BACKGROUND Adipocytes,especially adipocytes within tumor tissue known as cancer-associated adipocytes,have been increasingly recognized for their pivotal role in the tumor microenvironment of gastric cancer(GC).Their ...
The“Basic Science Research Program”extended its support via the National Research Foundation of Korea (NRF),which is sponsored through the Ministry of Education (2018R1C1B6004780);supported by Main Research Program (E0211200-03)of the Korea Food Research Institute (KFRI)funded by the Ministry of Science and ICT。
The prevalence of obesity has increased and is a health concern worldwide.Due to the concerns regarding synthetic anti-obesity treatments,nowadays natural products become a trend.Previous studies proved that there is ...
supported by a project(32271220)from the National Natural Science Foundation of China to Jianping Ye。
Beige/brown adipocytes play a crucial role in regulating the body’s overall energy balance.The thermogenic function is under the influence of various tissues,including the brain,muscles,and liver.However,the breast t...