ENDOCANNABINOIDS

作品数:20被引量:16H指数:2
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相关领域:医药卫生更多>>
相关作者:朱超黄矛胡佳更多>>
相关机构:第二军医大学更多>>
相关期刊:《Asian Pacific Journal of Tropical Biomedicine》《Journal of Traditional Chinese Medicine》《Journal of Animal Science and Biotechnology》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金更多>>
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Lipolysis pathways modulate lipid mediator release and endocannabinoid system signaling in dairy cows'adipocytes
《Journal of Animal Science and Biotechnology》2024年第6期2366-2382,共17页Madison N.Myers Miguel Chirivi Jeff C.Gandy Joseph Tam Maya Zachut G.Andres Contreras 
funded by the Michigan Animal Agricultural Alliance competitive project#AA-23–0014;United States Department of Agriculture National Institute of Food and Agriculture(USDA)projects#2019–67015-29443 and#2021–67037-34657;the United States-Israel Binational Agricultural Research Development(BARD)Fund project#IS-5167–19;the Office for the Associate Dean of Research at Michigan State University;supported by USDA National Institute of Food and Agriculture’s Agriculture and Food Research Initiative Educational Workforce and Development Program award#2024-67011-42947。
Background As cows transition from pregnancy to lactation,free fatty acids(FFA)are mobilized from adipose tissues(AT)through lipolysis to counter energy deficits.In clinically healthy cows,lipolysis intensity is reduc...
关键词:Adipose tissue Dairy cows Endocannabinoid system ENDOCANNABINOIDS LIPOLYSIS 
Cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies
《Neural Regeneration Research》2024年第4期788-799,共12页R.Scott Duncan Sean M.Riordan Matthew C.Gernon Peter Koulen 
supported in part by grants from the National Institute on Aging and National Eye Institute[EY030747(3R01EY030747-02S2)and EY031248(3R01EY03124802S1)]of the National Institutes of Health(to PK);Additional support by the Felix and Carmen Sabates Missouri Endowed Chair in Vision Research;the Vision Research Foundation of Kansas City。
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the human body.They have been studied in cellular and animal models as well as in human clinical trials for th...
关键词:ANANDAMIDE CANNABIDIOL cannabinoid ENDOCANNABINOID epilepsy multiple sclerosis neurodegeneration neuroprotection TETRAHYDROCANNABINOL 
SPME as a green sample-preparation technique for the monitoring of phytocannabinoids and endocannabinoids in complex matrices被引量:2
《Journal of Pharmaceutical Analysis》2023年第10期1117-1134,共18页Katarzyna Wozniczka PawełKonieczynski Alina Plenis Tomasz Ba˛czek Anna Roszkowska 
The endocannabinoid system(ECS),particularly its signaling pathways and ligands,has garnered considerable interest in recent years.Along with clinical work investigating the ECS’functions,including its role in the de...
关键词:Phytocannabinoids ENDOCANNABINOIDS Solid-phase microextraction Plant material Biological matrix 
Endocannabinoids are potential inhibitors of glioblastoma multiforme proliferation
《Journal of Integrative Medicine》2023年第2期120-129,共10页Ashraf Duzan Desiree Reinken Timothy L.McGomery Nicholas M.Ferencz Jacob M.Plummer Mufeed M.Basti 
Globally,it is evident that glioblastoma multiforme(GBM)is an aggressive malignant cancer with a high mortality rate and no effective treatment options.Glioblastoma is classified as the stage-four progression of a gli...
关键词:GLIOBLASTOMA ENDOCANNABINOIDS CERAMIDE APOPTOSIS CHEMOTHERAPY Cancer 
Activation of the endocannabinoid system mediates cardiac hypertrophy induced by rosiglitazone
《Acta Pharmacologica Sinica》2022年第9期2302-2312,共11页Ya-han Liu Yan Liu Xu Zhang Li Fang Bei-lei Zhao Nan-ping Wang 
This study was supported by grants from the National Key R&D Program of China[2018YFA0800600];National Science Foundation of China[81830015,82170422 and 81670408].
Rosiglitazone(RSG)is a synthetic agonist of peroxisome proliferator-activated receptor-γ(PPARγ),which plays a central role in the regulation of metabolism.Meta-analyses have suggested that RSG is associated with inc...
关键词:peroxisome proliferator-activated receptor-γ ENDOCANNABINOIDS cardiac hypertrophy mammalian target of rapamycin 
A proposed modulatory role of the endocannabinoid system on adipose tissue metabolism and appetite in periparturient dairy cows被引量:2
《Journal of Animal Science and Biotechnology》2021年第3期995-1007,共13页Madison N.Myers Maya Zachut Joseph Tam G.Andres Contreras 
This project was funded by the US-Israel Binational Agricultural Research and Development Fund(Grant IS-5167-19);MNS was supported in part by the USDA National Institute for Food and Agriculture(Washington,DC,USA)competitive project 2019-67015-29443.
To sustain the nutrient demands of rapid fetal growth,parturition,and milk synthesis,periparturient dairy cows mobilize adipose tissue fatty acid stores through lipolysis.This process induces an inflammatory response ...
关键词:ADIPOGENESIS Adipose tissue Dairy cow health ENDOCANNABINOIDS Endocannabinoid system LIPOGENESIS LIPOLYSIS 
Endocannabinoids regulate fear memory generalization via hippocampal local circuits
《解剖学杂志》2021年第S01期83-83,共1页Ge Qian Han Jing 
Generalization is widely accepted as adaptive behavioral conditions that allow individuals to quickly respond to similar circumstances.But once overgeneralization occurs,e.g.due to the inability to suppress generalize...
关键词:GENERALIZATION ENDOGENOUS PRECISE 
Cannabinoid CB_(2) receptors and spinal microglia are implicated in tingenone-mediated antinociception in mice
《Asian Pacific Journal of Tropical Biomedicine》2021年第4期141-147,共7页Clarice C.V.Moura Rafaela S.dos Santos Lucienir P.Duarte Giovane Galdino 
supported by the Coordenacao de Aperfeicoamento de Pessoal de Nível Superior-Brasil(CAPES)(Finance Code 001)
Objective:To investigate the antinociceptive effect of tingenone on inflammatory pain,as well as and the involvement of the cannabinoid receptors type 2(CB2)and spinal microglia in this process.Methods:Male Swiss mice...
关键词:Tingenone ANTINOCICEPTION CB2 Cannabinoid receptor ENDOCANNABINOIDS MICROGLIA 
Genome-wide analysis of hippocampal transfer RNA-derived small RNAs identifies new potential therapeutic targets of Bushen Tiansui formula against Alzheimer’s disease被引量:1
《Journal of Integrative Medicine》2021年第2期135-143,共9页Zhe-yu Zhang Chun-hu Zhang Jing-jing Yang Pan-pan Xu Peng-ji Yi Mu-li Hu Wei-jun Peng 
supported by the National Natural Science Foundation of China(No.81603670,81873169);the Hunan Provincial Natural Science Foundation of China(No.2017JJ3459,2020JJ4803)。
Objective:Bushen Tiansui formula(BSTSF),a traditional Chinese medicine prescription,has been widely used to treat Alzheimer’s disease(AD).However,the mechanisms underlying its effects remain largely unknown.In this s...
关键词:Traditional Chinese medicine Alzheimer’s disease ENDOCANNABINOIDS HIPPOCAMPUS Small non-coding RNAs Transfer RNA 
Endogenous cannabinoids may regulate chronic inflammation in aspirin-exacerbated respiratory disease被引量:1
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2020年第4期255-257,共3页Joshua M.Levy 
The National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR002378 and KL2TR002381.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Aspirin-exacerbated respiratory disease(AERD)is characterized by the triad of chronic rhinosinusitis with nasal polyposis,adult-onset asthma and non-IgE mediated reactions to aspirin and other cyclooxygenase-1(COX-1)i...
关键词:Chronic rhinosinusitis Aspirin-exacerbated respiratory disease Endogenous cannabinoid ENDOCANNABINOIDS EICOSANOIDS PROSTAGLANDINS 
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