ENDOCANNABINOID

作品数:21被引量:72H指数:4
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相关领域:医药卫生更多>>
相关作者:吴宗贵梁春周卫建陈玮更多>>
相关机构:第二军医大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Neuroimmunology and Neuroinflammation》《World Journal of Neurology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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The Modulating Role of Cannabis in Insomnia: A Review of the Literature
《Journal of Behavioral and Brain Science》2024年第9期255-264,共10页Ana Carolina Perin Spenassato Manoella Feltrin Orsato Márcio Silveira Correa 
The objective of this study was to carry out a review of the literature covering the topic of the association between sleep, insomnia and the medicinal use of cannabis. The guiding question for carrying out this study...
关键词:CANNABIS CANNABIDIOL Tetrahidrocanabinol INSOMNIA ENDOCANNABINOID 
Cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies
《Neural Regeneration Research》2024年第4期788-799,共12页R.Scott Duncan Sean M.Riordan Matthew C.Gernon Peter Koulen 
supported in part by grants from the National Institute on Aging and National Eye Institute[EY030747(3R01EY030747-02S2)and EY031248(3R01EY03124802S1)]of the National Institutes of Health(to PK);Additional support by the Felix and Carmen Sabates Missouri Endowed Chair in Vision Research;the Vision Research Foundation of Kansas City。
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the human body.They have been studied in cellular and animal models as well as in human clinical trials for th...
关键词:ANANDAMIDE CANNABIDIOL cannabinoid ENDOCANNABINOID epilepsy multiple sclerosis neurodegeneration neuroprotection TETRAHYDROCANNABINOL 
Endocannabinoid control of neuroinflammation in traumatic brain injury by monoacylglycerol lipase in astrocytes
《Neural Regeneration Research》2023年第5期1023-1024,共2页Chu Chen 
supported by National Institutes of Health grants No. R01NS076815, R01MH113535, and R01AG058621。
Traumatic brain injury(TBI)is a temporary or permanent disruption of brain function caused by external forces.TBI has been recognized as an important risk factor for the development of Alzheimer’s disease and dementi...
关键词:inflammation ALZHEIMER TBI 
Endocannabinoid metabolism and Alzheimer’s disease
《Neural Regeneration Research》2022年第9期1987-1988,共2页Chu Chen 
supported by National Institutes of Health grants R01NS076815,R01MH113535,and R01AG058621(to CC).
Alzheimer’s disease(AD)is the most common cause of dementia in the elderly.Unfortunately,there are no effective therapies currently available for prevention and treatment of AD.As it is clear now,the etiology of AD i...
关键词:METABOLISM ALZHEIMER protective 
Lignans from <i>Morinda citrifolia</i>(Noni) Fruit Inhibit Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase <i>in Vitro</i>
《Journal of Biosciences and Medicines》2020年第3期143-152,共10页Brett J. West Shixin Deng Claude Jarakae Jensen 
Morinda citrifolia (noni) fruit juice has exhibited a variety of biological activities in human clinical trials, indicating that it influences multiple systems of the body. Since the 1990s, the endocannabinoid system ...
关键词:MORINDA citrifolia NONI ENDOCANNABINOID System Fatty Acid Amide Hydrolase MONOACYLGLYCEROL Lipase 
Function of the Endocannabinoid System in Neurodegenerative Diseases and Cancers
《American Journal of Plant Sciences》2019年第10期1839-1854,共16页Mario Soliman Shobha Potlakayala Dhimant Desai Hannah Weeden Rabab Husain Nicole Lookfong Thomas Trite John Spagnola Shantu Amin Sairam Rudrabhatla 
Neurodegenerative diseases are characterized by progressive degeneration and/or death of neuronal cells and results in a wide array of cognitive impairments and other serious neurological defects. The signaling pathwa...
关键词:CANNABINOID ENDOCANNABINOID System NEURODEGENERATIVE DISORDERS CANCER 
<i>Morinda citrifolia</i>(Noni) Fruit Juice Inhibits Endocannabinoid Degradation Enzymes
《Journal of Biosciences and Medicines》2019年第7期22-34,共13页Brett J. West Shixin Deng C. Jarakae Jensen 
Morinda citrifolia (noni) fruit juice has been shown to have a wide variety of potential health benefits in human clinical trials. It may also influence the endocannabinoid system of the body. Since the main ingredien...
关键词:MORINDA citrifolia ENDOCANNABINOID System Fatty Acid Amide Hydrolase MONOACYLGLYCEROL Lipase 
Heterogeneity of cannabinoid ligand-induced modulations in intracellular Ca^2+ signals of mouse pancreatic acinar cells in vitro被引量:1
《Acta Pharmacologica Sinica》2019年第3期410-417,共8页Kun-kun Xia Jian-xin Shen Ze-bing Huang Hui-min Song Ming Gao De-jie Chen Shui-jun Zhang Jie Wu 
We recently reported that a CB2R agonist,GW405833(GW),reduced both the ACh-induced Ca^2+ oscillations and the L-arginineinduced Ca2+signal enhancement in mouse pancreatic acinar cells,suggesting that GW-induced inhibi...
关键词:CANNABINOID CB2 RECEPTOR CB1 RECEPTOR ENDOCANNABINOID Ca^2+ oscillations pancreatic acinar cells PATCH-CLAMP 
Integrating endocannabinoid signaling in the regulation of anxiety and depression被引量:10
《Acta Pharmacologica Sinica》2019年第3期336-341,共6页An-qi Yin Feng Wang Xia Zhang 
Shaanxi Province Natural Science Foundation(No.2016JQ8024);International Cooperation and Exchange of the National Natural Science Foundation of China(No.81420108013).
Brain endogenous cannabinoid(eCB)signaling seems to harmonize appropriate behavioral responses,which are essential for the organism’s long-term viability and homeostasis.Dysregulation of eCB signaling contributes to ...
关键词:endocannabinoid(eCB) CANNABINOID 1 receptor(CB1R) ANXIETY DEPRESSION neural circuits 
Endocannabinoid signaling in psychiatric disorders:a review of positron emission tomography studies
《Acta Pharmacologica Sinica》2019年第3期342-350,共9页Matthew E.Sloan Caroline W.Grant Joshua L.Gowin Vijay A.Ramchandani Bernard Le Foll 
Endocannabinoid signaling is implicated in an array of psychopathologies ranging from anxiety to psychosis and addiction.In recent years,radiotracers targeting the endocannabinoid system have been used in positron emi...
关键词:positron emission tomography CANNABINOID receptors ENDOCANNABINOIDS fatty acid amide hydrolase MONOACYLGLYCEROL lipases cannabis use disorder ALCOHOLISM schizophrenia post-traumatic stress DISORDERS feeding and eating DISORDERS 
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