CANNABINOID

作品数：65被引量：66H指数：4
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相关领域：医药卫生更多>>
相关作者：陈秀丽杨莉戴二黑王翀奎叶立红更多>>
相关机构：石家庄市第五医院河北中医学院华中科技大学第二军医大学更多>>
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相关基金：国家自然科学基金王宝恩肝纤维化研究基金河北省卫生厅指令性课题更多>>
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Cannabinoid Modulation of Monoamine Levels in Mouse Brain:Unveiling Neurochemical Dynamics through an Innovative High‑performance Liquid Chromatography‑Fluorescence Detection Bioanalysis
《Journal of Analysis and Testing》2024年第3期300-314,共15页Fonseca Carla Cunha Susana Ferreira Ricardo Lapo Pais Mariana Goncalves Joana Camins Antoni Ettcheto Miren Barbosa Rui Fortuna Ana 
supported by funds from Fundacao para a Ciencia e a Tecnologia(FCT),Portugal,European Union,MCTES,and Fundo Social Europeu(FSE)in the scope of the Centro 2020 Regional Operational Programme(Carla’s PhD research grant 2021.06135;BD and Mariana’s PhD research grant 2020.6582.BD);supported by FCT Exploratory Project 2022.01066.PTDC,COMPETE and FEDER funds,FCT,Portugal.Figures 1 and 2 were created with BioRender.com.
Homeostasis of monoaminergic pathways is compromised in aging and neurodegenerative/neurological diseases such as Alzheimer’s disease and depression.On the other hand,their modulation has also been linked to the mech...
关键词：NEUROTRANSMITTER HPLC Mice Brain Prefrontal cortex CANNABINOID 
Partially substituting alfalfa hay with hemp forage in the diet of goats improved feed efficiency,ruminal fermentation pattern and microbial profiles被引量：1
《Animal Nutrition》2024年第2期49-60,共12页Tao Ran Zhipeng Xu Wenzhu Yang Dalin Liu Duanqin Wu 
funded by the National Key Research and Development Program of China(2021YFD1300504);“Double First Class”Special Guidance Project,Team Building Funds,Research Startup Funds(561120213);Lanzhou University,Lanzhou,China,High-end Foreign Experts Recruitment Plan(G2023175005L);The Agricultural Science and Technology Innovation Program,Chinese Academy of Agricultural Sciences(ASTIP-IBFC).
The use of hemp as a forage source in livestock diets has been less studied because bioactive residues in animal tissues may pose a risk to consumers.This study investigated the effects of partial substitution of alfa...
关键词：Alfalfa hay Hemp forage Growth performance Ruminal microbiota Cannabinoid metabolism GOAT 
Repurposing lansoprazole to alleviate metabolic syndrome via PHOSPHO1 inhibition
《Acta Pharmaceutica Sinica B》2024年第4期1711-1725,共15页Yingting Wu Jiaqi Xin Xinyu Li Ting Yang Yi Liu Yongsheng Zhao Wen Xie Mengxi Jiang 
This work was supported by the Beijing Municipal Natural Science Foundation Grant 7212148(to Mengxi Jiang,China);the National Natural Science Foundation of China Grant 82000807(to Mengxi Jiang,China);the Beijing Municipal Education Commission Grant KM202110025023(to Mengxi Jiang,China).
Drug repurposing offers an efficient approach to therapeutic development.In this study,our bioinformatic analysis first predicted an association between obesity and lansoprazole(LPZ),a commonly prescribed drug for gas...
关键词：LANSOPRAZOLE Proton pump inhibitors Adipose thermogenesis Energy expenditure Metabolic syndrome PHOSPHO1 inhibitor Cannabinoid receptor signaling Drug repurposing 
Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis被引量：3
《Horticulture Research》2023年第9期306-320,共15页Ziyan Xie Yaolei Mi Lingzhe Kong Maolun Gao Shanshan Chen Weiqiang Chen Xiangxiao Meng Wei Sun Shilin Chen Zhichao Xu 
supported by the National Natural Science Foundation of China(82204579);the Fundamental Research Funds for the Central Universities(2572022DX06);the Scientific and Technological Innovation Project of China Academy of Chinese Medical Science(CI2021A04113);Heilongjiang Touyan Innovation Team Program(Tree Genetics and Breeding Innovation Team).
Is Cannabis a boon or bane?Cannabis sativa has long been a versatile crop for fiber extraction(industrial hemp),traditional Chinese medicine(hemp seeds),and recreational drugs(marijuana).Cannabis faced global prohibit...
关键词：COMPREHENSIVE VERSATILE globally 
Induction of Anxiety-Like Phenotypes by Knockdown of Cannabinoid Type-1 Receptors in the Amygdala of Marmosets被引量：1
《Neuroscience Bulletin》2023年第11期1669-1682,共14页Lin Zhu Di Zheng Rui Li Chen-Jie Shen Ruolan Cai Chenfei Lyu Binliang Tang Hao Sun Xiaohui Wang Yu Ding Bin Xu Guoqiang Jia Xinjian Li Lixia Gao Xiao-Ming Li 
supported by the Zhejiang Province Natural Science Foundation of China(LD22H090003);Key-Area Research and Development Program of Guangdong Province(2019B030335001 and 2018B030334001);the National Natural Science Foundation of China(31871070,82090031,32071097,31871056,and 32170991);the Key R&D Program of Zhejiang Province(2020C03009);Fundamental Research Funds for the Central Universities(2021FZZX001-37);the CAMS Innovation Fund for Medical Sciences(2019-I2M-5-057).
The amygdala is an important hub for regulating emotions and is involved in the pathophysiology of many mental diseases,such as depression and anxiety.Meanwhile,the endocannabinoid system plays a crucial role in regul...
关键词：Cannabinoid type-1 receptor AMYGDALA MARMOSET ANXIETY CRISPR/Cas9 
Protective effect of intervention with cannabinoid type-2 receptor agonist JWH133 on pulmonary fibrosis in mice
《China Medical Abstracts(Internal Medicine)》2023年第3期173-174,共2页吴潇 
Objective JWH133,a cannabinoid type 2 receptor agonist,was tested for its ability to protect mice from bleomycin-induced pulmonary fibrosis.Methods By using a random number generator,24 C57BL/6J male mice were randoml...
关键词：JWH133 C57BL/6J PULMONARY 
Severe Hypophosphatemia in Adolescent Cannabis User
《Open Journal of Pediatrics》2023年第4期496-501,共6页Chantel Johnson Michael J. Thomas Michael Halata Dmitry Samsonov 
Cannabinoid hyperemesis syndrome (CHS) involves cyclical nausea, vomiting, and abdominal pain linked to use of cannabis with resolution of symptoms upon cessation of cannabinoids. Although electrolyte disturbances, fl...
关键词：CANNABINOID TOXICITY HYPEREMESIS 
Role of Cannabinoid CB1 Receptor in Object Recognition Memory Impairment in Chronically Rapid Eye Movement Sleep-deprived Rats
《Chinese Medical Sciences Journal》2023年第1期29-37,共9页Kaveh Shahveisi Seyedeh Marziyeh Hadi Hamed Ghazvini Mehdi Khodamoradi 
Supported by the Research Council of Kermanshah University of Medical Sciences,Kermanshah,Iran for financial support(grant no.:990812).
Objective We aimed to investigate whether antagonism of the cannabinoid CB1 receptor(CB1R)could affect novel object recognition(NOR)memory in chronically rapid eye movement sleep-deprived(RSD)rats.Methods The animals ...
关键词：REM sleep deprivation novel object recognition memory cannabinoid CB1 receptor RIMONABANT 
Cloning Successive Generations of Industrial Hemp (Cannabis sativa) to Assess Cannabinoid Profiles
《Agricultural Sciences》2022年第12期1291-1308,共18页Cassandra Perrone Paul Kline John DuBois 
Industrial hemp (Cannabis sativa) has made a remarkable impact worldwide due to the plant’s beneficial properties and versatile use. Vegetative cuttings (clones) of C. sativa are the preferred propagation technique t...
关键词：Industrial Hemp CANNABIS CLONING CANNABINOIDS 
Repeated cocaine administration upregulates CB_(2) receptor expression in striatal medium-spiny neurons that express dopamine D_(1) receptors in mice
《Acta Pharmacologica Sinica》2022年第4期876-888,共13页Hai-Ying Zhang Lindsay De Biase Ramesh Chandra Hui Shen Qing-Rong Liu Eliot Gardner Mary Kay Lobo Zheng-Xiong Xi 
This research was supported by the Intramural Research Program(IRP)of the National Institute on Drug Abuse(NIDA)(DA000633-01);National Institutes of Health(NIH);grant support for MKL in UMB(NIH grant R01DA038613).
Cannabinoid CB2 receptors(CB2R)are importantly involved in drug reward and addiction.However,the cellular mechanisms underlying CB2R action remain unclear.We have previously reported that cocaine self-administration u...
关键词：COCAINE CANNABINOID CB_(2)receptor MICROGLIA SELF-ADMINISTRATION D_(1)-MSNs 
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