云南高校图书馆联盟文献共享服务平台- RIMONABANT

RIMONABANT: 作品数：16被引量：15H指数：2; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：陆林徐彬许学书王宇晓程莹更多>>; 相关机构：华东理工大学北京大学上海第二医科大学附属仁济医院中国人民解放军总医院更多>>; 相关期刊：《国外药讯》《世界临床药物》《Chinese Medical Sciences Journal》《中国药物应用与监测》更多>>; 相关基金：国家自然科学基金更多>>

Role of Cannabinoid CB1 Receptor in Object Recognition Memory Impairment in Chronically Rapid Eye Movement Sleep-deprived Rats: 《Chinese Medical Sciences Journal》2023年第1期29-37,共9页Kaveh Shahveisi Seyedeh Marziyeh Hadi Hamed Ghazvini Mehdi Khodamoradi; Supported by the Research Council of Kermanshah University of Medical Sciences,Kermanshah,Iran for financial support(grant no.:990812).; Objective We aimed to investigate whether antagonism of the cannabinoid CB1 receptor(CB1R)could affect novel object recognition(NOR)memory in chronically rapid eye movement sleep-deprived(RSD)rats.Methods The animals ...; 关键词：REM sleep deprivation novel object recognition memory cannabinoid CB1 receptor RIMONABANT

Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin: 《Acta Pharmacologica Sinica》2019年第3期418-424,共7页Alex Perchuk Sonya M.Bierbower Ana Canseco-Alba Zoila Mora Lauren Tyrell Neal Joshi Norman Schanz Georgianna G.Gould Emmanuel S.Onaivi; Despite the apparent abundance of ligand-gated transient receptor potential vanilloid type 1(TRPV1)and possible cross talk between the endocannabinoid and endovanilloid systems in the central nervous system(CNS),it is...; 关键词：vanilloids CANNABINOIDS conditioned place preference PRENATAL exposure plus-maze REWARD CAPSAICIN WIN55212-2 CAPSAZEPINE RIMONABANT

WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats: 《Acta Pharmacologica Sinica》2013年第1期119-128,共10页Jing SUN Yin-quan FANG Hong REN Tao CHEN Jing-jing GUO Jun YAN Shu SONG Lu-yong ZHANG Hong LIAO; Acknowledgements This research was supported in part by the National Natural Science Foundation of China （No 81070967） and the Natural Science Foundation of Jiangsu Province （No BK2009296）. We wish to thank Su-juan YUAN in Yancheng City No I People＇s Hospital for technological assistance.; Aim： To explore whether the synthetic cannabinoid receptor agonist WIN55,212-2 could protect oligodendrocyte precursor cells （OPCs） in stroke penumbra, thereby providing neuroprotection following permanent focal ce...; 关键词：STROKE permanent focal cerebral ischemia PENUMBRA oligodendrocyte precursor cells neural glial antigen 2 （NG2） tau-1 cannabinoid receptor type 1 （CB1） WIN55 212-2 RIMONABANT

Rise and fall of anti-obesity drugs被引量：7: 《World Journal of Diabetes》2011年第2期19-23,共5页Bernard MY Cheung; Although it is not generally a life-threatening disease,obesity is becoming a major health problem worldwide.It can be controlled by means of drugs,and,consequently,these are required to be safe as well as effective.I...; 关键词：OBESITY ANTI-OBESITY DRUGS SIBUTRAMINE RIMONABANT ORLISTAT

Rimonabant inhibits TNF-α-induced endothelial IL-6 secretion via CB1 receptor and cAMP-dependent protein kinase pathway被引量：1: 《Acta Pharmacologica Sinica》2010年第11期1447-1453,共7页Nan-lan HUANG Jyh-ming JUANG Yi-ho WANG Chia-hsiang HSUEH Yao-jen LIANG Jiunn-lee LIN Chia-ti TSAI Ling-ping LAI; Aim： To investigate whether rimonabant, a cannabinoid receptor antagonist, had inhibitory effects on inflammatory reactions in human umbilical vein endothelial cells （HUVEC）. Methods： TNF-α-induced IL-6 productio...; 关键词：RIMONABANT CB1 receptor cAMP-dependent protein kinase endothelial cells inflammation

The endocannabinoid system:A new pharmacological target for obesity treatment?: 《Neuroscience Bulletin》2009年第3期153-160,共8页胡佳朱超黄矛; supported by the Study Grant (2007) for Medical Students of Second Military Medical University,China; Being a great threaten for human health, obesity has become a pandemic chronic disease. There have been several therapeutic treatments for this social health issue, including diet and exercise therapy, medication and ...; 关键词：OBESITY weight loss ENDOCANNABINOIDS cannabinoid receptor cannabinoid CB1 receptor antagonist anti-obesity agents RIMONABANT

Rimonabant可能引起精神病学的不良事件: 《国外药讯》2008年第3期39-39,共1页钱苏宁（摘）; 根据丹麦研究者进行的荟萃分析的结果，尽管rimonabant（Ⅰ）似乎是减轻体重的有效治疗方法，但是它的使用可能会导致抑郁情感障碍、焦虑等精神性的不良事件。; 关键词：不良事件精神病学荟萃分析治疗方法减轻体重情感障碍研究者精神性

ADR风向标: 《中国处方药》2007年第11期20-21,共2页许关煜; 西布曲明关键词：禁忌证和心血管不良反应；磷酸二酯酶-5抑制剂关键词：修改标签；莫达非尼关键词：更新安全性信息；氯苯胺丁醇关键词：引起心脏问题；Rimonabant关键词：严重精神障碍。; 关键词：磷酸二酯酶-5抑制剂 RIMONABANT ADR 心血管不良反应风向严重精神障碍关键词西布曲明

Rimonabant:一种有希望的代谢综合征治疗药物被引量：1: 《中国药物应用与监测》2007年第3期47-50,共4页程莹潘长玉; 代谢综合征(MS)是包括肥胖、高血压、高血糖、血脂紊乱等代谢异常的集合体。Rimonabant通过对大麻素受体1(CB1)的拮抗作用,抑制endocannabinoid系统(EC系统),发挥抑制食欲、减少摄食、减轻体重的作用。正在进行的Ⅲ期临床研究结果显示,...; 关键词：代谢综合征大麻素受体肥胖 RIMONABANT

新型减肥药利莫纳班的离子阱质谱和电子轰击质谱研究被引量：3: 《分析测试学报》2007年第z1期50-52,共3页王宇晓许学书; Rimonabant was studied by ESI ion trap mass spectrometry and EI(electron impact) time-of-flight mass spectrometry.m/z 380.9 can be used for identification of this drug by LC-MS.An exact mass at m/z 462.0782 (calculate...; 关键词：RIMONABANT ESI Ion trap mass spectrometry EI Time of flight mass spectrometry

RIMONABANT