CAPSAICIN

作品数：88被引量：170H指数：6
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相关领域：医药卫生更多>>
相关作者：张世红马晓丽张旭赵晏张方雄更多>>
相关机构：山东大学山西医科大学西安交通大学中国科学院上海生命科学研究院更多>>
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相关基金：国家自然科学基金山西省自然科学基金中国博士后科学基金国家高技术研究发展计划更多>>
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Single-cell transcriptomics illustrates the immune inflammatory responses of septic mice spleen after capsaicin treatment
《Genes & Diseases》2025年第1期9-13,共5页Weijin Qiu Qian Zhang Jing Liu Xueling He Guangqing Cheng Jiayun Chen Yunmeng Bai Piao Luo Ping Gong Fei Shi Jigang Wang 
supported by the Establishment of Sino-Austria“Belt and Road”Joint Laboratory on Traditional Chinese Medicine for Severe Infectious Diseases and Joint Research(No.2020YFE0205100);the National Key Research and Development Program of China(No.2020YFA0908000);the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(China)(No.ZYYCXTD-C-202002);the National Natural Science Foundation of China(No.82074098,81841001);the Fundamental ResearchFunds for the Central Public Welfare Research Institutes(China)(No.ZZ13-ZD-07,ZXKT18003,ZZ14-YQ-050,ZZ14-ND-010,ZZ15-ND-10,ZZ14-FL-002,ZZ14-YQ059,ZZ15-YQ-063);Shenzhen Science and Technology Innovation Commission(Guangdong,China)(No.JCYJ20210324115800001 and JCYJ20210324114014039);the National Key R&D Program of China Key projects for international cooperation on science,technology and innovation(No.2020YFE0205100);the Shenzhen Medical Research Fund of Shenzhen Medical Academy of Research and Translation(Guangdong,China)(No.B2302051);the Distinguished Expert Project of Sichuan Province Tianfu Scholar(China)(No.CW202002);China Academy of Chinese MedicalSciencess(CACMS)InnovationFund(No.CI2023E002);State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs.
Sepsis,a life-threatening condition triggered by a dysregulated host response to infection,remains a major challenge for therapeutic intervention.Despite the growing interest in immunomodulatory strategies for sepsis ...
关键词：inflammatory CAPSAICIN TREATMENT 
Capsaicin(CAP)exerts a protective effect against ethanol-induced oxidative gastric mucosal injury by modulating the chemokine receptor 4(CCR4)/Src/p47phox signaling pathway both in vitro and in vivo
《Chinese Journal of Natural Medicines》2025年第2期191-202,共12页Zhiru Yang Haolin Guo Pengfei Zhang Kairui Liu Junli Ba Xue Bai Shiti Shama Bo Zhang Xiaoning Gao Jun Kang 
supported by the High-level Talent Research Start-up Project Funding of Henan Academy of Sciences (No.252028037)。
Ethanol(EtOH)is a common trigger for gastric mucosal diseases,and mitigating oxidative stress is essential for attenuating gastric mucosal damage.Capsaicin(CAP)has been identified as a potential agent to counteract ox...
关键词：CAPSAICIN Gastric mucosal damage Chemokine signaling NF-κB p65 
Capsaicin alleviates the hepatic clock gene disruption and gut microbiota dysbiosis in circadian rhythm disorder mouse model
《Food Science and Human Wellness》2024年第5期2947-2958,共12页Bolin Lin Chi-Tang Ho Yawen Wang Jie Xiao Muwen Lu 
supported by the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2019ZT08N291);the Science and Technology Program of Guangzhou,China(2023A04J0760);the Guangdong Basic and Applied Basic Research Foundation(2024A1515030058).
As the body’s internal clock,the circadian rhythm regulates the energy expenditure,appetite,and sleep.There exists a close relationship between the host circadian rhythm and gut microbiota.In this work,a circadian di...
关键词：CAPSAICIN Circadian rhythm Hepatic clock gene Gut microbiota Lipid dysregulation 
Author correction to“Identification of the dietary supplement capsaicin as an inhibitor of Lassa virus entry”[Acta Pharmaceutica Sinica B 10(2020)789-798]
《Acta Pharmaceutica Sinica B》2024年第7期3294-3294,共1页Ke Tang Xiaoyu Zhang Ying Guo 
The authors regret that there is an error in Fig.2B(Page 793),in which the fluorescence image of the“DMSO(Before&during low pH treatment)”group was mistakenly pasted in the process of assembling figures.This correct...
关键词：CORRECTION FIGURES image 
Transient receptor potential vanilloid 1 involved in the analgesic effects of total flavonoids extracted from Longxuejie(Resina Dracaenae Cochinchinensis)被引量：1
《Journal of Traditional Chinese Medicine》2024年第3期437-447,共11页MO Xiaoqiang CHEN Yating YIN Qian CHEN Haibo BAN Qiang LI Jun CHEN Su YAO Jinguang 
High Level Talents Project of Affiliated Hospital of Youjiang Medical University for Nationalities:Study of Soft-Du'an Capsule's Mechanism and Efficacy of Regulating TRPV1 Pashways in Relieving Oral and Maxillofacial Trigeminal Neuralgia (No. YYFYR20213002);Innovative Group Project of Natural Science Foundation of Hubei Province:Study on the Mechanisms of Pain Signal Transduction and Drug Analgesia (No. 2020CFA025)。
OBJECTIVE: To evaluate the analgesic effects of total flavonoids of Longxuejie(Resina Dracaenae Cochinchinensis)(TFDB) and explore the possible analgesic mechanism associated with transient receptor potential vanilloi...
关键词：Freund's adjuvant FORMALDEHYDE CAPSAICIN FLAVONOIDS Longxuejie(Resina Dracaenae Cochinchinensis) transient receptor potential vanilloid 1 inflammatory pain 
Capsaicin functions as a selective degrader of STAT3 to enhance host resistance to viral infection被引量：1
《Acta Pharmacologica Sinica》2023年第11期2253-2264,共12页Mei-qi Zhang Xin Jia Cui-qin Cheng Yu-xi Wang Yi-ying Li Ling-dong Kong Qi-qi Li Fang Xie Yan-li Yu Yu-ting He Qiu-tong Dong Zhan-hong Jia Yao Wang An-long Xu 
Fundamental Research Funds for the Central Universities(No.2023-JYB-KYPT-06);Young Elite Scientists Sponsorship Program by China Association for Science and Technology(No.2020-QNRC1-03);the National Natural Science Foundation(NNSF)of China(Nos.82001663).
Although STAT3 has been reported as a negative regulator of type I interferon (IFN) signaling, the effects of pharmacologically inhibiting STAT3 on innate antiviral immunity are not well known. Capsaicin, approved for...
关键词：viruses CAPSAICIN type I interferons STAT3 protein degradation 
Capsaicin exerts anti-benign prostatic hyperplasia effects via inhibiting androgen receptor signaling pathway
《BIOCELL》2023年第6期1389-1396,共8页ZICHEN SHAO CHUNG-YI CHEN XUZHOU CHEN HANWU CHEN MENGQIAO SU HUI SUN YIDAN LI BINGHUA TU ZITONG WANG CHI-MING LIU 
Yichun University Local Development Research Center(Grant No.DF2019002);the PhD Research Foundation of Yichun University(Grant No.211-3360118006);the Animal Care and Ethics Committee of Yichun University(Approval No.2022026).
Background:Benign prostatic hyperplasia(BPH)is a common condition in middle-aged and elderly men.Enlargement of the prostate causes lower urinary tract symptoms.Capsaicin is a phytochemical extracted from chili pepper...
关键词：BPH Apoptosis AUTOPHAGY CAPSAICIN Chili pepper 5Α-REDUCTASE 
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function被引量：3
《Acta Pharmacologica Sinica》2023年第4期766-779,共14页Jing-xian Sun Ke-ying Zhu Yu-meng Wang Dan-jie Wang Mi-zhen Zhang Heela Sarlus Irene Benito-Cuesta Xiao-qiang Zhao Zao-feng Zou Qing-yang Zhong Yi Feng Shuai Wu Yan-qing Wang Robert A.Harris Jun Wang 
supported by the National Natural Science Foundation of China(82074538,81671597);the Innovative Research Team of High-Level Local Universities in Shanghai(2019-2023);the Shanghai Municipal Science and Technology Major Project(No.2018SHZDZX01);the Development Project of Shanghai Peak Disciplines-Integrated Chinese and Western Medicine.KZ was sponsored by China Scholarship Council(201700260280).
The transient receptor potential vanilloid 1(TRPV1)is a non-selective cation channel that is activated by capsaicin(CAP),the main component of chili pepper.Despite studies in several neurological diseases,the role of ...
关键词：TRPV1 CAPSAICIN microglia REMYELINATION phagocytosis 
Role of transient receptor potential vanilloid-1 in behavioral thermoregulation of the Mongolian gerbil Meriones unguiculatus被引量：1
《Integrative Zoology》2022年第4期608-618,共11页Jing WEN Tingbei BO Zhijun ZHAO Dehua WANG 
This work was supported by the National Natural Science Foundation of China(No.31970417 and 31772461)to DHW;the State Key Laboratory of Integrated Management of Pest Insects and Rodents(Grant No.IPM2004).
Ambient temperature considerably affects the physiology and behavior of mammals.Thermosensory and thermoregulatory abilities play an important role in the response to changing ambient temperature in endotherms.However...
关键词：brown adipose tissue(BAT) CAPSAICIN Mongolian gerbils protein kinase A(PKA) transient receptor potential vanilloid-1(TRPV1) 
Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity被引量：1
《World Journal of Clinical Cases》2022年第1期79-90,共12页Unal Atas Nuray Erin Gokhan Tazegul Gulsum Ozlem Elpek Bülent Yıldırım 
BACKGROUND Transient receptor potential vanilloid-1(TRPV1),a nonselective cation channel,is activated by capsaicin,a pungent ingredient of hot pepper.Previous studies have suggested a link between obesity and capsaici...
关键词：CAPSAICIN Transient receptor potential vanilloid 1 IMMUNOHISTOCHEMISTRY Morbid obesity OBESITY Transient receptor potential channels Transient receptor potential vanilloid cation channels 
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