CANNABIDIOL

作品数：44被引量：62H指数：5
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相关机构：沈阳药科大学哈尔滨医科大学台湾大学中国药品生物制品检定所更多>>
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The Modulating Role of Cannabis in Insomnia: A Review of the Literature
《Journal of Behavioral and Brain Science》2024年第9期255-264,共10页Ana Carolina Perin Spenassato Manoella Feltrin Orsato Márcio Silveira Correa 
The objective of this study was to carry out a review of the literature covering the topic of the association between sleep, insomnia and the medicinal use of cannabis. The guiding question for carrying out this study...
关键词：CANNABIS CANNABIDIOL Tetrahidrocanabinol INSOMNIA ENDOCANNABINOID 
Pharmacologic Effects of Cannabidiol and Its Molecular Mechanism
《Plant Diseases and Pests》2024年第4期43-46,共4页Jundong GUAN Anqi WANG Jiazhu LI Jingjing WEN Changtao CAI Chenghao JIN 
Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16);Heilongjiang Provincial Key Research and Development Plan Guidance Project(GZ20220039).
Cannabidiol(CBD)is the active constituent of Cannabis sativa and exhibits a diverse range of pharmacologic effects,including anticancer,antibacterial,anti-inflammatory,antioxidant,and antiepileptic properties.The phar...
关键词：CANNABIDIOL ANTICANCER ANTIBACTERIAL ANTI-INFLAMMATORY Antioxidant ANTIEPILEPTIC 
Cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies
《Neural Regeneration Research》2024年第4期788-799,共12页R.Scott Duncan Sean M.Riordan Matthew C.Gernon Peter Koulen 
supported in part by grants from the National Institute on Aging and National Eye Institute[EY030747(3R01EY030747-02S2)and EY031248(3R01EY03124802S1)]of the National Institutes of Health(to PK);Additional support by the Felix and Carmen Sabates Missouri Endowed Chair in Vision Research;the Vision Research Foundation of Kansas City。
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the human body.They have been studied in cellular and animal models as well as in human clinical trials for th...
关键词：ANANDAMIDE CANNABIDIOL cannabinoid ENDOCANNABINOID epilepsy multiple sclerosis neurodegeneration neuroprotection TETRAHYDROCANNABINOL 
A Systematic Review of Cannabidiol Effects in Coronary Syndromes: Challenges to Clinical Translation
《Journal of Biosciences and Medicines》2024年第4期246-263,共18页Mario E. Zuñiga-Ayala Alejandra Meaney-Martínez Alejandro Alcocer-Chauvet Vidal Gonzalez-Coronado Nestor Rubio-Infante Gerardo Garcia-Rivas 
Background: Myocardial ischemia in addition to other several cardiac syndromes represent a pathological proinflammatory state alongside a complex cellular microenvironment that can be modified by using cannabinoids. C...
关键词：CANNABIS CANNABIDIOL Acute Coronary Syndromes Myocardial Infarction Myocardial Ischemia and Oxidative Stress 
Pharmacodynamic study of cannabidiol on bleomycin-induced pulmonary fibrosis in rats
《Journal of Hainan Medical University》2023年第22期1-8,共8页SUN Meng-di ZHANG Fei-yu GAO Xin WANG Yu CHEN Ping-ping LIU Shu-min 
Post-doctoral Program of Heilongjiang Province (No.LBH-Z22251);Chinese Medicine Research Project of Heilongjiang Province (No.ZHY2022-114);Heilongjiang Chinese Medicine Association Youth Talent Promotion Project (No.2022-QNRC1-27)。
Objective:To study the protective effect of cannabidiol(CBD)on rats with pulmonary fibrosis and explore the possible mechanism of the use of CBD in the treatment of pulmonary fibrosis.Methods:Sixty SD rats were random...
关键词：CANNABIDIOL Pulmonary fibrosis INFLAMMATION Oxidative stress PHARMACODYNAMICS 
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy
《Acta Pharmaceutica Sinica B》2023年第11期4591-4606,共16页Chang Xiao Yue Sun Jialong Fan William Nguyen Simin Chen Ying Long Wei Chen Aiguo Zhu Bin Liu 
partially supported by the Natural Science Foundation of Hunan Province(2020JJ4005,2020JJ5421,2021JJ30096,China);National Natural Science Funds of China(82003931);The China Postdoctoral Science Foundation(2021M690974,China);Agricultural Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences(CAAS-ASTIP-IBFC04,China);Opening foundation of Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province(2022CG01,China);Key Research and Development Projects in Ningxia Autonomous Region(2022BFH02013,China)。
Although carbon monoxide(CO)-based treatments have demonstrated the high cancer efficacy by promoting mitochondrial damage and core-region penetrating ability,the efficiency was often compromised by protective autopha...
关键词：Carbon monoxide therapy CANNABIDIOL Reactive oxygen species Excessive autophagy Autophagic flux Autolysosome degradation METASTASES Triple-negative breast cancer 
Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer被引量：2
《Journal of Pharmaceutical Analysis》2023年第7期726-744,共19页Xiaofan Sun Lisha Zhou Yi Wang Guoliang Deng Xinran Cao Bowen Ke Xiaoqi Wu Yanhong Gu Haibo Cheng Qiang Xu Qianming Du Hongqi Chen Yang Sun 
supported by the National Key Research and Development Plan,China(Grant No.:2022YFC3500202);the Natural Science Foundation of China(Grant Nos.:82172558,and 82205024);the Scientific and Technological Innovation Action Plan of Natural Science Foundation Project of Shanghai,China(Grant No.:22ZR1447400);the Scientific and Technological Innovation Action Plan,China(Grant No.:22ZR1447400);the Fundamental Research Funds for the Central Universities,China(Grant Nos.:020814380179,020814380174);the Distinguished Young Scholars of Nanjing,China(Grant No.:JQX20008);the School of Life Science(NJU)-Sipimo Joint Funds and Mountain Climbing Talents Project of Nanjing University,China(Grant No.:2015018).
Colorectal tumors often create an immunosuppressive microenvironment that prevents them from responding to immunotherapy.Cannabidiol(CBD)is a non-psychoactive natural active ingredient from the cannabis plant that has...
关键词：scRNA-seq scATAC-seq CANNABIDIOL Colorectal cancer Tumor microenvironment MACROPHAGE 
Cannabidiol-Mediated Sequestration of Alzheimer’s Amyloid-β Peptides in ADDL Oligomers
《American Journal of Molecular Biology》2023年第2期113-126,共14页Yang Li Fengyuan Zhang Caroline E. Herron Ivonne Rosales Alejandro Heredia Nicolae-Viorel Buchete Brian J. Rodriguez 
Cannabidiol (CBD), one of the most studied phytocannabinoids, is non-psychotropic and can induce protective effects on the central nervous system against acute and chronic brain injury. Interestingly, CBD inhibits pro...
关键词：CANNABIDIOL AMYLOID Alzheimer’s Amyloid-β Peptides Aβ-Derived Diffusible Ligands Atomic Force Microscopy Amyloid Peptide Sequestration 
Neuroprotective potential of cannabidiol:Molecular mechanisms and clinical implications
《Journal of Integrative Medicine》2023年第3期236-244,共9页Srushti M.Tambe Suraj Mali Purnima D.Amin Mozaniel Oliveira 
Cannabidiol(CBD),a nonpsychotropic phytocannabinoid that was once largely disregarded,is currently the subject of significant medicinal study.CBD is found in Cannabis sativa,and has a myriad of neuropharmacological im...
关键词：Cannabis sativa CANNABIDIOL Natural products Bioactive compounds Anti-neurodegenerative diseases 
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats
《Acta Pharmacologica Sinica》2023年第3期499-512,共14页Bing-tian Xu Meng-fan Li Ke-chun Chen Xing Li Ning-bo Cai Jiang-ping Xu Hai-tao Wang 
National Natural Science Foundation of China(Nos.82173802 and 82273902);Science and Technology Program of Guangzhou(No.202002030494);Guangdong Basic and Applied Basic Research Foundation(No.2022A1515012317).
Cannabidiol(CBD)reportedly exerts protective effects against many psychiatric disorders and neurodegenerative diseases,but the mechanisms are poorly understood.In this study,we explored the molecular mechanism of CBD ...
关键词：CANNABIDIOL MFN2 PARKIN cerebral ischemia oxidative stress 
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