METASTASES

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Plasma extracellular cold inducible RNA-binding protein levels are elevated for 1 month post-colectomy which may promote metastases
《World Journal of Gastrointestinal Oncology》2025年第4期318-326,共9页H M C Shantha Kumara Poppy Addison Xiao-Hong Yan Anuj Raj Sharma Neil Mitra Hansani N Angammana Yanni Hedjar Yi-Ru Chen Vesna Cekic Whelan L Richard 
BACKGROUND Cold-inducible RNA-binding protein(CIRP)is related to a family of stressinduced RNA-binding proteins.It is primarily found in the nucleus,where it regulates transcription.Under stress,CIRP translocates to t...
关键词：Effects of surgery Plasma extracellular cold-inducible RNA-binding protein levels Colorectal resection Colorectal cancer Angiogenesis 
Despicable role of epithelial-mesenchymal transition in breast cancer metastasis:Exhibiting de novo restorative regimens
《Cancer Pathogenesis and Therapy》2025年第1期30-47,共18页Paras Famta Saurabh Shah Biswajit Dey Kondasingh Charan Kumar Deepkumar Bagasariya Ganesh Vambhurkar Giriraj Pandey Anamika Sharma Dadi ASrinivasarao Rahul Kumar Santosh Kumar Guru Rajeev Singh Raghuvanshi Saurabh Srivastava 
Breast cancer(BC)is the most prevalent cancer in women globally.Anti-cancer advancements have enabled the killing of BC cells through various therapies;however,cancer relapse is still a major limitation and decreases ...
关键词：BREASTCANCER Epithelial-to-mesenchymal transition METASTASES Cancer stem cells EPIGENETICS 
Anlotinib plus chemotherapy as afirst-line treatment for gastrointestinal cancer patients with unresectable liver metastases:a multicohort,multicenter,exploratory trial
《Signal Transduction and Targeted Therapy》2025年第1期303-313,共11页Jun-Wei Wu Chen-Fei Zhou Zheng-Xiang Han Huan Zhang Jun Yan Jun Chen Chun-Bin Wang Zhi-Quan Qin Yong Mao Xin-Yu Tang Liang-Jun Zhu Xiao-Wei Wei Dong-Hai Cui Xiu-Li Yang Min Shi Li-Qin Zhao Jin-Ling Jiang Wei-You Zhu Hong-Mei Wang Chun Wang Ling-Jun Zhu Jun Zhang 
supported by the National Natural Science Foundation of China(82273126 and 82273407);the Collaborative Innovation Cluster Project of the Shanghai Municipal Health Commission(grant number,2020CXJQ03);the Innovative research teams of high-level local universities in Shanghai.The authors thank all patients,their families,investigators,and research staffs for participating in this trial.
This multicohort phase II trial(ALTER-G-001;NCT05262335)aimed to assess the efficacy offirst-line anlotinib plus chemotherapy for gastrointestinal(GI)cancer patients with unresectable liver metastases.Eligible patient...
关键词：patients METASTASES GASTROINTESTINAL 
Unraveling the routes to distant metastases in colorectal cancer:Tumor deposits and lymph node metastases as the gateway
《Cancer Communications》2024年第10期1209-1213,共5页Nelleke Pietronella Maria Brouwer Ayse Selcen Oguz Erdogan Shannon van Vliet Natasja Rutgers Nikki Knijn Gesina van Lijnschoten Jessica Juliana Tan Johannes Hendrik Willem de Wilt Niek Hugen Gina Brown Femke Simmer Iris Dionne Nagtegaal 
supported by the Dutch Cancer Society(KUN 2019-12640).
Currently,lymph node metastases(LNM)are seen as the gateway to distant metastases in CRC and play a crucial role in the Tumor Node Metastasis(TNM)staging system[1,2].Tumor deposits(TD)have been identified as another h...
关键词：METASTASES CANCER GATEWAY 
Clinicopathological analysis of small intestinal metastasis from extra-abdominal/extra-pelvic malignancy
《World Journal of Gastrointestinal Oncology》2024年第10期4138-4145,共8页Zhi Zhang Jing Liu Peng-Fei Yu Hai-Rui Yang Jin-Yang Li Zhi-Wei Dong Wei Shi Guo-Li Gu 
Supported by Outstanding Young Talents Program of Air Force Medical Center,People’s Liberation Army,No.22BJQN004;Clinical Program of Air Force Medical University,No.Xiaoke2022-07.
BACKGROUND The metastatic tumors in the small intestine secondary to extra-abdominal/extrapelvic malignancy are extremely rare.However,the small intestine metastases are extremely prone to misdiagnosis and missed diag...
关键词：Small intestinal METASTASES Clinicopathological features Prognostic analysis MALIGNANCY 
In situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases
《Acta Pharmaceutica Sinica B》2024年第9期4102-4117,共16页Yuan Li Fan Tong Yufan Wang Jing Wang Manqi Wu Hanmei Li Hongyan Guo Huile Gao 
the National Natural Science Foundation of China(No.82102769);the 111 Project(No.B18035,China);the Fundamental of Research Funds for the Central Universities and Beijing Natural Science Foundation(No.L212054,China).
Tumor vaccine,a promising modality of tumor immunotherapy,needs to go through the process of tumor antigen generation and loading,antigen drainage to lymph nodes(LNs),antigen internalization by dendritic cells(DCs),DC...
关键词：In situ nano-vaccine Lymph node targeting MMP-2 responsive PD-1 Combination therapy CPG Ovarian cancer METASTASES 
Stage Ⅳ non-small cell lung cancer with multiple metastases to the small intestine leading to intussusception: A case report
《World Journal of Clinical Cases》2024年第26期5960-5967,共8页Qi-Guang Niu Min-Hao Huang Wei-Qi Kong Yang Yu 
BACKGROUND Gastrointestinal tract metastasis from lung cancer is rare and compared to small cell lung cancer(SCLC),non-SCLC(NSCLC)is even less likely to metastasize in this manner.Additionally,small intestinal tumors ...
关键词：Non-small cell lung cancer Brain metastases ablation Small bowel metastases Small bowel resection Case report 
Wrecking neutrophil extracellular traps and antagonizing cancer-associated neurotransmitters by interpenetrating network hydrogels prevent postsurgical cancer relapse and metastases被引量：1
《Bioactive Materials》2024年第9期14-24,共11页Hang Zhou Chunyan Zhu Qing Zhao Jinliang Ni Haipeng Zhang Guangcan Yang Jianchao Ge Chao Fang Hong Wei Xianli Zhou Kun Zhang 
supported by National Natural Science Foundation of China for Youth Scholars(Grant No.82022033,82202241);Heilongjiang Postdoctoral Science Foundation(Grant No.LBH-Z21022),China Postdoctoral Science Foundation(Grant No.2022MD713749);Sichuan Provincial Science Foundation for Distinguished Young Scholars(24NSFJQ0038).
Tumor-promoting niche after incomplete surgery resection(SR)can lead to more aggressive local progression and distant metastasis with augmented angiogenesis-immunosuppressive tumor microenvironment(TME).Herein,elevate...
关键词：Neutrophil extracellular traps Cancer-associated neurotransmitters Interpenetrating network hydrogels Postsurgical cancer relapse and metastases Immunosuppressive tumor microenvironment 
Endobronchial metastasis secondary to renal clear cell carcinoma:A case report
《World Journal of Clinical Cases》2024年第23期5416-5421,共6页Tian-Hao Xie Yan Fu Si-Ning Ha Qing-Xu Meng Qian Sun Pan Wang 
BACKGROUND Endobronchial metastases(EBMs)are tumours that metastasise from a malignant tumour outside the lungs to the central and subsegmental bronchi,and are visible under a bronchofibrescope.Most EBMs are formed by...
关键词：Endobronchial metastases Clear renal cell carcinoma Renal cell carcinoma DIAGNOSIS TREATMENT Case report 
MRI-guided photothermal/photodynamic immune activation combined with PD-1 inhibitor for the multimodal combination therapy of melanoma and metastases
《Regenerative Biomaterials》2024年第4期38-51,共14页Changqiang Wu Wei Chen Shuang Yan Jie Zhong Liang Du Chenwu Yang Yu Pu Yang Li Jiafu Lin Mei Zeng Xiaoming Zhang 
supported by National Natural Science Foundation of China[grant number 81601490];Natural Science Foundation of Sichuan Province[grant number 2022NSFSC0636];Science and Technology Project of Municipal School Strategic Cooperation,Nanchong[grant number 20SXQT0306];Pre-research Project of North Sichuan Medical College[grant number CBY19-YZ05];Open Research Program of Antibiotic Research and Reevaluation Key Laboratory of Sichuan Province[grant number ARRLKF20-03];Scientific Research Start-up Fund of North Sichuan Medical College[grant number CBY22-QDA03].
Non-invasive image-guided precise photothermal/photodynamic therapy(PTT/PDT)has been proven to be an effective local treatment modality but incompetent against metastases.Hence,the combination of local PTT/PDT and sys...
关键词：photothermal therapy photodynamic therapy IMMUNOTHERAPY magnetic resonance imaging multimodal treatment 
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