云南高校图书馆联盟文献共享服务平台- TETRAHYDROCANNABINOL

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Cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies: 《Neural Regeneration Research》2024年第4期788-799,共12页R.Scott Duncan Sean M.Riordan Matthew C.Gernon Peter Koulen; supported in part by grants from the National Institute on Aging and National Eye Institute[EY030747(3R01EY030747-02S2)and EY031248(3R01EY03124802S1)]of the National Institutes of Health(to PK);Additional support by the Felix and Carmen Sabates Missouri Endowed Chair in Vision Research;the Vision Research Foundation of Kansas City。; Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the human body.They have been studied in cellular and animal models as well as in human clinical trials for th...; 关键词：ANANDAMIDE CANNABIDIOL cannabinoid ENDOCANNABINOID epilepsy multiple sclerosis neurodegeneration neuroprotection TETRAHYDROCANNABINOL

Anticancer activity of Δ^(9)-tetrahydrocannabinol and cannabinol in vitro and in human lung cancer xenograft被引量：1: 《Asian Pacific Journal of Tropical Biomedicine》2022年第8期323-332,共10页Surang Leelawat Kawin Leelawat Thaniya Wannakup Worawan Saingam Nanthaphong Khamthong Fameera Madaka Athip Maha Patamaporn Pathompak Lukman Sueree Thanapat Songsak; the Research Institute,Rangsit University(grant number 103/2561,2018)and by the College of Pharmacy,Rangsit University.; Objective:To investigate the effects of Δ^(9)-tetrahydrocannabinol,the principal psychoactive compound of Cannabis sativa,and cannabinol,a Δ^(9)-tetrahydrocannabinol degradative product,on human non-small cell lung ...; 关键词：CANNABIS Δ9-Tetrahydrocannabinol Cannabinol Non-small cell lung cancer AKT Cannabis sativa Glycogen synthase kinase 3 alpha/beta Endothelial nitric oxide synthase

Role of cannabinoids and the endocannabinoid system in modulation of diabetic cardiomyopathy被引量：2: 《World Journal of Diabetes》2022年第5期387-407,共21页Mona F El-Azab Ahmed E Wakiel Yossef K Nafea Mahmoud E Youssef; Diabetic complications,chiefly seen in long-term situations,are persistently deleterious to a large extent,requiring multi-factorial risk reduction strategies beyond glycemic control.Diabetic cardiomyopathy is one of ...; 关键词：Δ9-tetrahydrocannabinol AUTOPHAGY Cannabinoid receptors Diabetic cardiomyopathy Endocannabinoid system INFLAMMATION

Δ<sup>9</sup>-Tetrahydrocannabinol Produced Positive Place Preference in Mice without Significant <i>Ex-Vivo</i>Effect on Hepatic Arylamine N-Acetyltransferase Activity: Implications for Its Addictive Liability and Absence of Effect on Xenobiotic Metabolism: 《Journal of Behavioral and Brain Science》2021年第8期179-192,共14页Lauriann Young Karen Thaxter Danielle Campbell Sheena Francis Nicola Laurieri Rupika Delgoda; Aim: Δ⁹-Tetrahydrocannabinol (Δ⁹-THC) is a potentially addictive cannabinoid. Its impact on the activity of liver arylamine N-Acetyltransferase (NAT) has not been reported. This study in...; 关键词：CANNABIS Marijuana Conditioned Place Preference Addiction Drug Reward

Preparation of cannabidiol and its application in daily chemical industry: 《China Detergent & Cosmetics》2020年第4期14-18,共5页Yang Jiarui; Cannabidiol(CBD)is a physiologically active natural substance,usually extracted from the flowers and leaves of hemp.CBD not only has the function of alleviating the symptoms of many mental disorders,but also has the f...; 关键词：CANNABIDIOL CBD TETRAHYDROCANNABINOL THC skin care

Δ 9-Tetrahydrocannabinol Toxicity and Validation of Cannabidiol on Brain Dopamine Levels: An Assessment on Cannabis Duplicity: 《Natural Products and Bioprospecting》2020年第5期285-296,共12页Swapnali Chetia Gaurab Borah; The authors sincerely acknowledge the funding(Sanction Order No.DST/Inspire Fellowship/2016/IF160620);dated 01-22-2020 and support provided by the Department of Science and Technology,Govt.of India and University Grants Commission,New Delhi.; Δ9-tetrahydrocannabinol(THC)of cannabis is the main psychoactive component which is a global significant concern to human health.Evaluation on THC reported its drastic effect on the brain dopaminergic(DAergic)system ...; 关键词：CANNABIS TETRAHYDROCANNABINOL CANNABIDIOL DOPAMINE Medicinal uses

Chemical and physical variations of cannabis smoke from a variety of cannabis samples in New Zealand被引量：1: 《Forensic Sciences Research》2019年第2期168-178,共11页Thomas J.Sheehan Hilary J.Hamnett Richard Beasley Paul S.Fitzmaurice; supported by the Institute of Environmental Science and Research(ESR)and the Medical Research Institute of New Zealand(MRINZ).; Studies have compared the chemical properties of tobacco smoke to those of cannabis smoke,with the objective of identifying the chemical attributes responsible for the mutagenicity and carcinogenicity of cannabis smok...; 关键词：Forensic science forensic toxicology CANNABIS SMOKE delta-9-tetrahydrocannabinol TERPENOIDS gas chromatography/mass spectrometry total particulate matter

The dimerization of ⊿~9-tetrahydrocannabinolic acid A(THCA-A): 《Acta Pharmaceutica Sinica B》2019年第5期1078-1083,共6页Arben Cuadari Federica Pollastro Juan D.Unciti-Broceta Diego Caprioglio Alberto Minassi Annalisa Lopatriello Eduardo Munoz Orazio Taglialatela-Scafati Giovanni Appendino; financial support to the groups in Novara and Naples(PRIN2017,Project 2017WN73PL,bioactivity-directed exploration of thephytocannabinoid chemical space,Italy); The renewed interest in dimeric salicylates as broad-spectrum anti-inflammatory and antidiabetic agents provided a rationale to investigate the dimerization of the substituted salicylate D9-tetrahydrocannabinolic acid...; 关键词：Phytocannabinoids DIMERIZATION D9-Tetrahydrocannabinolic acid A D9-Tetrahydrocannabinol PPAR-g

CB1 receptor activation on VgluT2-expressing glutamatergic neurons underlies Δ9-tetrahydrocannabinol(Δ9-THC)-induced aversive effects in mice: 《中国药理学与毒理学杂志》2018年第9期715-716,共2页HAN Xiao HE Yi BI Guo-hua ZHANG Hai-ying SONG Rui LI Jin XI Zheng-xiong; OBJECTIVE Cannabis can be rewarding or aversive.Cannabis reward is believed to be mediated by activation of cannabinoid CB1 receptors(CB1 Rs) on GABAergic neurons that disinhibit dopaminergic neurons in the ventral te...; 关键词：CANNABIS CANNABINOID receptor type 1 RNAscope conditioned KNOCK-OUT intracrnialself-stimulation

S4A-1 Cognitive and Pharmacological Assays to Characterize both the Deleterious and Medicinal Effects of Cannabinoids in Monkeys: 《神经药理学报》2018年第4期63-64,共2页Brian D Kangas; Rationale:Marijuana is the most commonly used illicit drug in the United States with recent surveys estimating over 22 million current users.However,there is growing acceptance of its recreational use,evident by succe...; 关键词：delta-9-tetrahydrocannabinol(THC) phyto-cannabinoids

TETRAHYDROCANNABINOL