ANANDAMIDE

作品数：23被引量：17H指数：2
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相关领域：医药卫生更多>>
相关作者：李茜张翼马会杰苏彦欣史敏更多>>
相关机构：河北医科大学华中科技大学复旦大学中国药科大学更多>>
相关期刊：《Journal of Pharmaceutical Analysis》《中国老年学杂志》《中国医院药学杂志》《中华实验外科杂志》更多>>
相关基金：国家自然科学基金教育部留学回国人员科研启动基金重庆市自然科学基金更多>>
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A New Process of Synthesizing Anandamide Derivatives from Arachidonic Acid in the Presence of Boron Catalyst
《International Journal of Organic Chemistry》2024年第4期128-134,共7页Mohammad Al-Masum Linda Quinones 
Anandamide is part of the cannabinoid group and functions as a neurotransmitter. Anandamide plays a role in depression, pain, appetite, memory, and fertility. Since it is well documented that anandamide analog behaves...
关键词：ANANDAMIDE CROSS-COUPLING MICROWAVE Alcohol Amines 
Cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies
《Neural Regeneration Research》2024年第4期788-799,共12页R.Scott Duncan Sean M.Riordan Matthew C.Gernon Peter Koulen 
supported in part by grants from the National Institute on Aging and National Eye Institute[EY030747(3R01EY030747-02S2)and EY031248(3R01EY03124802S1)]of the National Institutes of Health(to PK);Additional support by the Felix and Carmen Sabates Missouri Endowed Chair in Vision Research;the Vision Research Foundation of Kansas City。
Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a variety of effects in the human body.They have been studied in cellular and animal models as well as in human clinical trials for th...
关键词：ANANDAMIDE CANNABIDIOL cannabinoid ENDOCANNABINOID epilepsy multiple sclerosis neurodegeneration neuroprotection TETRAHYDROCANNABINOL 
Medicinal cannabis products for the treatment of acute pain
《World Journal of Clinical Cases》2023年第12期2670-2676,共7页Marco Fiore Aniello Alfieri Sveva Di Franco Stephen Petrou Giovanni Damiani Maria Caterina Pace 
For thousands of years,medicinal cannabis has been used for pain treatment,but its use for pain management is still controversial.Meta-analysis of the literature has shown contrasting results on the addition of cannab...
关键词：CANNABIS CANNABINOIDS Endocannabinoid system 2-arachidonoylglycerol ANANDAMIDE ANALGESIA Acute pain 
Brain activity of anandamide:a rewarding bliss?被引量：2
《Acta Pharmacologica Sinica》2019年第3期309-323,共15页Maria Scherma Paolo Masia Valentina Satta Walter Fratta Paola Fadda Gianluigi Tanda 
Anandamide is a lipid mediator that acts as an endogenous ligand of CB1 receptors.These receptors are also the primary molecular target responsible for the pharmacological effects of Δ9-tetrahydrocannabinol,the psych...
关键词：ENDOCANNABINOIDS 2-AG ANANDAMIDE CANNABINOID receptor brain reward DRUG use disorder DRUG addiction FAAH COCAINE morphine nicotine alcohol 
CYP4X1的结构、分布、表达调控及功能的研究进展被引量：1
《中国医院药学杂志》2018年第18期1985-1988,共4页余绪明 骆霞 王佳 王林海 余世荣 
CYP4X1是CYP4新的亚家族成员,也是重要的Orphans CYPs成员之一。其核苷酸序列同源性分析显示CYP4X1结构在跨物种间是高度保守的,这预示着它具有重要的生物学功能。CYP4X1广泛存在于人体各组织中,尤其选择性在脑内高表达,提示其可能在神...
关键词：CYP4X1 细胞色素P450酶系 CYP4 ANANDAMIDE 14 15-EET-EA EETS 
The Endocannabinoid,Anandamide,Induces Cannabinoid Receptor-Independent Cell Death in Renal Proximal Tubule Cells
《CellBio》2017年第4期35-55,共21页Monika Schlosser Heike Loser Soren V.Siegmund Manuel Montesinos-Rongen Laura Bindila Beat Lutz David A.Barrett Sarir Sarmad Catharine A.Ortori Veronika Grau Melanie von Brandenstein Jochen W.U.Fries 
supported by Koeln Fortune Program/Faculty of Medicine,University of Cologne and excellence cluster initiative supported by University of Cologne and DFG.
Background: The endocannabinoid (EC) system is well characterized in the central nervous system but scarcely studied in peripheral organs. In this paper, we newly identify the effect of the EC anandamide (AEA) upon re...
关键词：ANANDAMIDE Cell Death RPTEC Caki-1 Endocannabinoid Receptor 
Anandamide Depresses Glycinergic and GABAergic Inhibitory Transmissions in Adult Rat Substantia Gelatinosa Neurons
《Pharmacology & Pharmacy》2015年第3期103-117,共15页Yasuhiko Kawasaki Tsugumi Fujita Kun Yang Eiichi Kumamoto 
Cannabinoid CB1 receptors have been found in the superficial dorsal horn of the spinal cord, particularly the substantia gelatinosa (SG), which is thought to play a pivotal role in modulating nociceptive transmission....
关键词：Spinal Dorsal Horn CANNABINOID CB1 Receptor IPSC PATCH-CLAMP Pain 
Regulatory effects of anandamide on intracellular Ca^(2+) concentration increase in trigeminal ganglion neurons
《Neural Regeneration Research》2014年第8期878-887,共10页Yi Zhang Hong Xie Gang Lei Fen Li Jianping Pan Changjin Liu Zhiguo Liu Lieju Liu Xuehong Cao 
supported by NIH,grant No.GM-63577;NNSF,grant No.30571537,No.30271500;the National Natural Science Foundation of China,No.30271500,30571537 and 81370246;2010 National Clinical Key Disciplines Construction Grant from the Ministry of Health of the People’s Republic of China
Activation of cannabinoid receptor type 1 on presynaptic neurons is postulated to suppress neu- ~ ~ ~ 2＋ ~ ~ 2＋ rotransmlsslon by decreasing Ca reflux through high voltage-gated Ca channels. However, recent studies...
关键词：nerve regeneration trigeminal ganglion NEURONS ENDOCANNABINOIDS ANANDAMIDE can-nabinoid receptor type 1 voltage-dependent calcium channels vanilloid receptor patch-damp tech-nique calcium cyclic adenosine monophosphate protein kinase protein kinase C NIH grant neuralregeneration 
Quantification of anandamide,oleoylethanolamide and palmitoylethanolamide in rodent brain tissue using high performance liquid chromatographyelectrospray mass spectroscopy被引量：1
《Journal of Pharmaceutical Analysis》2014年第4期234-241,共8页Daniel J.Liput Eleftheria Tsakalozou Dana C.Hammell Kalpana S.Paudel Kimberly Nixon Audra L.Stinchcomb 
supported by funding from the National Institute ofAlcohol Abuse and Alcoholism AA016959(KN),AA016499(KN)and AA019853(DJL)and the Kentucky Science andTechnology Corporation(KSTC-184-512-07-029;ALS)
Reported concentrations for endocannabinoids and related lipids in biological tissues can vary greatly; therefore, methods used to quantify these compounds need to be validated. This report describes a method to quant...
关键词：Endocarmabinoids Acylethanolamides ANANDAMIDE OEA PEA LC-MS 
Palmitoylethanolamide对脑缺血再灌注损伤作用的研究进展
《中风与神经疾病杂志》2012年第12期1140-1141,共2页刘雅洁 金永华 
脑缺血再灌注损伤（cerebral ischemia reperfusion）是指颅内动脉狭窄或闭塞,导致局部血流量降低或停止一段时间,脑血流恢复后,反而引起脑组织损伤加重的现象。十六酰胺乙醇（Palmitoylethanolamide,PEA）是酰基乙醇胺类（N-acyle-than...
关键词：脑缺血再灌注损伤 损伤作用 ANANDAMIDE ISCHEMIA 颅内动脉狭窄 内源性大麻素 乙醇胺类 局部血流量 
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