KNOCK-OUT

作品数:14被引量:154H指数:2
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相关领域:医药卫生生物学更多>>
相关作者:邵晓王伟颜灿群项文君王冰更多>>
相关机构:南京中医药大学华中农业大学华中科技大学国防科学技术大学更多>>
相关期刊:《Journal of Integrative Agriculture》《Food Science and Human Wellness》《World Journal of Gastroenterology》《原子核物理评论》更多>>
相关基金:国家自然科学基金更多>>
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Knock-out of GhPDCT with the CRISPR/Cas9 system increases the oleic acid content in cottonseed oil被引量:1
《Journal of Integrative Agriculture》2024年第10期3468-3471,共4页Tingwan Li Lu Long Yingchao Tang Zhongping Xu Guanying Wang Man Jiang Shuangxia Jin Wei Gao 
supported by the Science and Technology Innovation Talents in Universities of Henan Province,China(24HASTIT053);the National Natural Science Foundation of China(32172041);the Natural Science Foundation of Henan Province,China(232300421026);the Science and Technology Innovation 2030,China(2022ZD0402001-04)。
Cotton is a pivotal economic crop for natural textile fibers that also serves as an important source of edible oil(Long et al.2023).Cottonseed oil contains approximately14%oleic acid and 59%linoleic acid.An increase i...
关键词:CRISPR/Cas9 fibers SYSTEM 
Knock-out of BnHva22c reduces the susceptibility of Brassica napus to infection with the fungal pathogen Verticillium longisporum
《The Crop Journal》2024年第2期503-514,共12页Wanzhi Ye Roxana Hossain Michael Prbsting Abdallah Abdelmegid Mohamed Ali Lingyue Han Ying Miao Steffen Rietz Daguang Cai Dirk Schenke 
supported by Bundesministerium für Bildung und Forschung(BMBF,Grant no.031B0033C);Bundesministerium für Ernahrung und Landwirtschaft(BMEL,Grant no.22006516);Bundesanstalt für Landwirtschaft and Ernahrung(BLE,Grant No.2814IP004)。
Verticillium longisporum(Vl43)is a soilborne hemibiotrophic fungal pathogen causing stem striping on oilseed rape(OSR)and severe yield losses.Breeding for resistant varieties is the most promising approach to control ...
关键词:Hva22c Susceptibility factor CRISPR/Cas9 Brassica napus ARABIDOPSIS Verticillium longisporum Resistance breeding 
Variation in floral form of CRISPR knock-outs of the poplar homologs of LEAFY and AGAMOUS after FT heat-induced early flowering
《Horticulture Research》2023年第8期183-193,共11页Amy L.Klocko Estefania Elorriaga Cathleen Ma Steven H.Strauss 
We thank the Tree Biosafety and Genomics Research Cooperative(TBGRC)at Oregon State University,the USDA(award 2011-68005-30407,System for Advanced Biofuels Production From Woody Biomass In The Pacific Northwest);USDA Biotechnology Risk Assessment Grants(2011-68005-30407 and 2010-33522-21736);the NSF I/UCRC Center for Advanced Forestry(0736283).
Plant migration and gene flow from genetically modified or exotic trees to nearby lands or by crossing with wild relatives is a major public and regulatory concern.Many genetic strategies exist to mitigate potential g...
关键词:AGAMOUS flowers organs 
Maximizing recovery time between knock-out races improves sprint cross-country skiing performance被引量:1
《Journal of Sport and Health Science》2022年第1期21-29,共9页Kerry McGawley Coline Van Waerbeke Karl-Johan Westberg Erik P.Andersson 
supported by a general collaborative grant for winter sport research provided through Mid Sweden University and the?stersund municipality(reference number:2018/1758-500584)。
Background:In a sprint cross-country(XC)ski competition,the difference in recovery times separating the first and the second semi-final(SF)heats from the final(F)may affect performance.The aim of the current study was...
关键词:ENERGETICS Repeated sprints Roller skiing Simulated competition TACTICS 
Spectrum-effect relationship of immunologic activity of Ganoderma lucidum by UPLC-MS/MS and component knock-out method被引量:7
《Food Science and Human Wellness》2021年第3期278-288,共11页Changqin Li Yiping Cui Jie Lu Lijun Meng Changyang Ma Zhenhua Liu Yan Zhang Wenyi Kang 
This work was funded by the National Key R&D Program of China(2018YFD0400200);Key Project in Science and Technology Agency of Kaifeng City(1906006);Major Public Welfare Projects in Henan Province(201300110200).
This study was designed to elucidate the immunoregulation of Ganoderma lucidum.HPLC fingerprint and spectrum-effect relationship of G.lucidum were established to predict the active compounds and BP neural network mode...
关键词:Ganoderma lucidum RAW 264.7 cell Spectrum-effect relationships Component knock-out BP neural network 
CB1 receptor activation on VgluT2-expressing glutamatergic neurons underlies Δ9-tetrahydrocannabinol(Δ9-THC)-induced aversive effects in mice
《中国药理学与毒理学杂志》2018年第9期715-716,共2页HAN Xiao HE Yi BI Guo-hua ZHANG Hai-ying SONG Rui LI Jin XI Zheng-xiong 
OBJECTIVE Cannabis can be rewarding or aversive.Cannabis reward is believed to be mediated by activation of cannabinoid CB1 receptors(CB1 Rs) on GABAergic neurons that disinhibit dopaminergic neurons in the ventral te...
关键词:CANNABIS CANNABINOID receptor type 1 RNAscope conditioned KNOCK-OUT intracrnialself-stimulation 
300 MeV质子同步加速器概念设计优化(英文)
《原子核物理评论》2017年第2期158-163,共6页安宇文 纪红飞 王生 黄良生 
National Natural Science Foundation of China(11405189)~~
目前处于设计阶段的哈尔滨工业大学空间辐照效应装置,其核心部件是由1台10 MeV的注入器、1台300MeV的同步加速器以及输运线构成的加速器装置。同步加速器中引出的质子束流被用于辐照研究。基于装置的概念设计,优化了其同步加速器部分的...
关键词:太空辐照 磁聚焦结构设计 多圈注入 慢引出 RF knock-out方法 
Design study for a 500 MeV proton synchrotron with CSNS linac as an injector
《Chinese Physics C》2016年第9期151-155,共5页黄良生 纪红飞 王生 
Using the China Spallation Neutron Source(CSNS) linac as the injector, a 500 MeV proton synchrotron is proposed for multidisciplinary applications, such as biology, material science and proton therapy. The synchrotr...
关键词:CSNS proton synchrotron multi-turn injection slow extraction RF knock-out 
Targeted Mutagenesis in Zea mays Using TALENs and the CRISPR/Cas System被引量:141
《Journal of Genetics and Genomics》2014年第2期63-68,共6页Zhen Liang Kang Zhang Kunling Chen Caixia Gao 
supported by the National Natural Science Foundation of China (Grant Nos. 31271795 and 31200273)
Transcription activator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeats (CRISPR)/ CRISPR-associated (Cas) systems have emerged as powerful tools for genome editing ...
关键词:TAL-effector nucleases CRISPR/Cas system KNOCK-OUT Zea mays 
RF knock-out extraction in HITFiL被引量:1
《Chinese Physics C》2012年第10期1004-1008,共5页石健 杨建成 夏佳文 原有进 李杰 柴伟平 宋明涛 张小虎 
Supported by State Key Development Program of Basic Research of China (2010CB834204)
A compact facility for cancer therapy has been designed and is presently under construction. A slow beam extraction system using the RF-Knock Out method and 3rd-order resonance is adopted in the synchrotron of this fa...
关键词:RF-knock out slow extraction 3rd order resonance cancer therapy 
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