NEURODEGENERATIVE

作品数：108被引量：397H指数：11
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相关机构：武汉大学更多>>
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Polysialic acid-Siglec immune checkpoints of microglia and macrophages:Perspectives for therapeutic intervention
《Neural Regeneration Research》2026年第2期661-662,共2页Hauke Thiesler Herbert Hildebrandt 
Deutsche Forschungsgemeinschaft(DFG,German Research Foundation),project numbers 324633948 and 409784463(DFG grants Hi 678/9-3 and Hi 678/10-2,FOR2953)to HH;Bundesministerium für Bildung und Forschung-BMBF,project number 16LW0463K to HT.
Microglia are the resident macrophages of the central nervous system.They act as the first line of defense against pathogens and play essential roles in neuroinflammation and tissue repair after brain insult or in neu...
关键词：therapeutic intervention central nervous system immune checkpoints neurodegenerative demyelinating diseases borst MACROPHAGES polysialic acid SIGLEC MICROGLIA 
The subventricular zone structure, functionand implications for neurological disease
《Genes & Diseases》2025年第3期122-136,共15页Kaishu Li Yin Zheng Shubing Cai Zhiming Fan Junyi Yang Yuanrun Liu Shengqi Liang Meihui Song Siyuan Du Ling Qi 
supported by the Medical Scientific Research Foundation of Guangdong Province,China(No.A2022125,A2023486);the Medical Research Fund of the Qingyuan People’s Hospital(No.15001019002213);the National Natural Science Foundation of China(No.82203351);The Guangdong Basic and Applied Basic Research Foundation of China(No.2021A1515111095).
The subventricular zone (SVZ) is a region surrounding the lateral ventricles thatcontains neural stem cells and neural progenitor cells, which can proliferate and differentiateinto various neural and glial cells. SVZ ...
关键词：Glioblastoma multiforme Neural injury repair Neural stem cells NEURODEGENERATIVE Subventricular zone 
Nutritional and therapeutic benefits of coconut milk and its potential as a plant-based functional yogurt alternative:a review
《Food Science and Human Wellness》2025年第1期64-77,共14页Gengghatarani Gengan Nurul Solehah Mohd Zaini Nazamid Saari Anis Shobirin Meor Hussin Ahmad Haniff Jaafar Hanan Hasan Elicia Jitming Lim Wan Abd Al Qadr Imad Wan-Mohtar Muhamad Hafiz Abd Rahim 
Universiti Putra Malaysia Inisiatif Putra Siswazah Grant,with a reference to UPM.RMC.800-2/1/2022/GPIPS/9740400;Ministry of Higher Education,Malaysia(01-01-20-2323FR,with reference code:FRGS/1/2020/STG01/UPM/02/2)for the financial support。
Plant-based milks are on the rise due to an increased awareness of their sustainability and health benefits.Currently,dairy milk is the most nutritionally complete beverage,but it suffers from the presence of indigest...
关键词：Coconut milk Plant-based yoghurt Diabetes NEURODEGENERATIVE Saturated fat Functional food Probiotic 
Polyoxidovanadates a new therapeutic alternative for neurodegenerative and aging diseases被引量：1
《Neural Regeneration Research》2024年第3期571-577,共7页Sonia Irais Gonzalez-Cano Gonzalo Flores Jorge Guevara Julio Cesar Morales-Medina Samuel Treviño Alfonso Diaz 
funded by project from National Research System (CONACYT),Mexico (to SIGC)
Aging is a natural phenomenon characterized by a progressive decline in physiological integrity,leading to a deterioration of cognitive function and increasing the risk of suffering from chronic-degenerative diseases,...
关键词：Alzheimer’s disease ANTIDIABETIC brain cognition diabetes insulin NEURODEGENERATION NEUROINFLAMMATION oxidative stress Vanadium species 
Cell senescence,loss of splicing,and lipid metabolism in TDP-43-related neurodegenerative processes
《Neural Regeneration Research》2023年第8期1725-1726,共2页Pascual Torres Reinald Pamplona Manuel Portero-Otin 
the Instituto de Salud CarlosⅢ(PI 17-000134,PI 20-0155)to MPO;the Generalitat de Catalunya 2017SGR696 to RP;a"Margarita Salas"fellow from the Spanish Ministry of Universities[Financed by European Union-NextGenerationEl funds];a FUNDELA Grant,RedELA-Plataforma Investigación and the FundacióMiquel Valls(Jack Van den Hoek donation)(to MPO);FEDER funds are acknowledged("A way to make Europe")(to MPO)。
In recent work,we have shown that cell senescence of mouse fibroblasts in vitro associates with a build-up of cryptic exons in selected mRNAs,whose level is usually controlled by the activity of TAR DNA binding protei...
关键词：METABOLISM DEGENERATIVE 
Converging links between adult-onset neurodegenerative Alzheimer’s disease and early life neurodegenerative neuronal ceroid lipofuscinosis?被引量：1
《Neural Regeneration Research》2023年第7期1463-1471,共9页Marcel Klein Guido Hermey 
supported by the Deutsche Forschungsgemeinschaft(DFG,425373668,HE 3220/4-1)(to GH).
Evidence from genetics and from analyzing cellular and animal models have converged to suggest links between neurodegenerative disorders of early and late life.Here,we summarize emerging links between the most common ...
关键词：Alzheimer’s disease autophagy Batten disease CLN3 disease dementia ENDOSOME LYSOSOME neurodegeneration neuronal ceroid lipofuscinosis PRESENILIN 
Olfactory dysfunction as a common biomarker for neurodegenerative and neuropsychiatric disorders
《Neural Regeneration Research》2023年第5期1029-1030,共2页David Slabik Olga Garaschuk 
supported by the DFG grant GA 654/14-1 to OG;the PATE program of the Faculty of Medicine,Eberhard Karls University of Tübingen to DS。
The sense of smell supports the identification and the safety of food,warns of danger/predators,and plays a key role in mating(Croy and Hummel,2017;Kondo et al.,2020;Tzeng et al.,2021).Via connection to the limbic sys...
关键词：KONDO TEARS al. 
Triggering of Major Brain Disorders by Protons and ATP:The Role of ASICs and P2X Receptors
《Neuroscience Bulletin》2023年第5期845-862,共18页Andri Cherninskyi Maksim Storozhuk Oleksandr Maximyuk Vyacheslav Kulyk Oleg Krishtal 
supported by the National Research Foundation of Ukraine(https:/nrfu.org.ua/en/,2020.02/0263);Die Deutsche Forschungsgemeinschaft(https://www.dfg.del,441694049).
Adenosine triphosphate(ATP)is well-known as a universal source of energy in living cells.Less known is that this molecule has a variety of important signaling func-tions:it activates a variety of specific metabotropic...
关键词：ASICS P2X receptors STROKE Chronic pain EPILEPSY NEURODEGENERATIVE Psychiatric diseases 
Relative Molecular Similarity in Compound Structures Modulating Neurodegenerative Apoptosis
《Journal of Biosciences and Medicines》2023年第2期105-123,共19页Wynford Robert Williams 
Neurodegeneration is attributable to metabolic disturbances in the various cell types responsible for this condition, in respect of glucose utilisation and dysfunctional mitochondrial oxidative mechanisms. The propert...
关键词：APOPTOSIS CGMP NEURODEGENERATION NEUROTOXINS Molecular Similarity 
Autophagy and autophagy-related molecules in neurodegenerative diseases被引量：4
《Animal Models and Experimental Medicine》2023年第1期10-17,共8页Changsong Dou Yu Zhang Ling Zhang Chuan Qin 
National Natural Science Foundation of China grant(31970510,81941012);CAMS Innovation Fund for Medical Sciences(CIFMS)grant(2016-I2M-2-006,2016-I2M-1-010).
Autophagy is one of the degradation pathways to remove proteins or damaged or-ganelles in cells that plays an important role in neuroprotection.Different stages of autophagy are regulated by autophagy-related genes,an...
关键词：AUTOPHAGY MITOPHAGY NEURODEGENERATIVE TFEB 
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