Hepatic ischemia-reperfusion syndrome has been the subject of intensive study and experimentation in recent decades since it is responsible for the outcome of several clinical entities,such as major hepatic resections...
Cellular and mitochondrial membrane phospholipids provide the substrate for synthesis and release of prostaglandins in response to certain chemical,mechanical,noxious and other stimuli.Prostaglandin D_(2),prostaglandi...
The opioid epidemic has become one of the most concerning public health issues in the world, and currently does not have an adequate treatment available. It has been observed that, despite opioids being highly addicti...
Department of Biotechnology(Grant No.BT/PR28560/AAQ/3/919/2018);Department of Science and Technology under PURSE Program[Grant No.SR/PURSE Phase 2/42(G)]to SM;University Grants Commission,New Delhi for Senior Research Fellowship(F.No.16-9(June 2018)/2019(NET/CSIR),15/04/2019)to SG;DST,New Delhi through the award of INSPIRE Fellowship(NO:DST/INSPIRE/03/2015/005022)to SB;The authors are also thankful to Head,Department of Zoology,Visva-Bharati University,Santiniketan,India(grant number DST-FIST No.SR/FST/LS II-031/2013[C])for providing infrastructural facilities.
Reproduction in bony fish,specifically in the female teleost,encompasses well-defined stages,including growth and development,final oocyte maturation and finally ovulation-a pre-requisite for forming fertilizable fema...
Cyclooxygenases play a vital role in inflammation and are responsible for the production of prostaglandins.Two cyclooxygenases are described,the constitutive cyclooxygenase-1 and the inducible cyclooxygenase-2,for whi...
supported by grants from the INSERM(Peyruchaud O),the UniversitéClaude Bernard Lyon 1(Peyruchaud O);and the ANR grant BoneTAX(Grant No.ANR-20-CE14-0036-01)(Peyruchaud O);Saier L was the recipient of a fellowship from the French Ministère de l’Enseignement Supérieur et de la Recherche.Niazi H was supported by Higher Education Commission of Pakistan.This work was funded in part by the Else Kröner-Fresenius-Stiftung(Levkau B).
Bioactive lipids constitute a large family of molecules considered as inflammatory mediators.Among them,lysophosphatidic acid(LPA),sphingosine 1-phosphate(S1P),and eicosanoids(prostanoids such as PGE2 and leukotrienes...
The National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR002378 and KL2TR002381.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Aspirin-exacerbated respiratory disease(AERD)is characterized by the triad of chronic rhinosinusitis with nasal polyposis,adult-onset asthma and non-IgE mediated reactions to aspirin and other cyclooxygenase-1(COX-1)i...
Supported by Ministerio de Ciencia Innovación y Universidades,No.SAF2017-82436R and SAF2016-75004R;Comunidad de Madrid,No.S2017/BMD-3686;Fundación Ramón Areces,No.2016/CIVP18A3864;Instituto de Salud Carlos Ⅲ;by Fondos FEDER,No.Cibercv and Ciberehd
The biosynthesis of prostanoids is involved in both physiological and pathological processes. The expression of prostaglandin-endoperoxide synthase 2(PTGS2; also known as COX-2) has been traditionally associated to th...
This work was supported by the National Institutes of Health(NIH grant#K23HL111113 and#R01HL128241);by generous contributions from the Vinik and Kaye Families.
It is well-established that following ingestion of aspirin or any other inhibitor of cyclooxygenase-1, patients with Samter’s disease, or aspirin-exacerbated respiratory disease (AERD) develop the sudden onset of wor...
The field of neuroimmunology has expanded in recent years providing new insights and therapies into pathologies like stroke, autism, and depression. However, few works explore the relationship between inflammatory sti...