云南高校图书馆联盟文献共享服务平台- CYCLOOXYGENASE

CYCLOOXYGENASE: 作品数：126被引量：612H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杨智明方克伟贵平魏莲枝彭平更多>>; 相关机构：重庆医科大学附属第一医院南京医科大学昆明医科大学三峡大学人民医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划上海市自然科学基金更多>>

Study on the effect of platycodin D on HG-induced podocyte injury in mice and cyclooxygenase-2/nuclear factor KB pathway: 《China Medical Abstracts(Internal Medicine)》2024年第1期33-33,共1页戚婷; Objective To explore the effect of platycodin D(PD) on podocyte injury induced by high glucose and cyclooxygenase-2 (COX-2)/nuclear factor kappa B(NF-κB) pathway in mice.Methods MPC5 cells were divided into normal co...; 关键词：CYCLOOXYGENASE injury EFFECT

Correction:The cyclooxygenase-expressing mesenchyme resists intestinal epithelial injury by paracrine signaling被引量：1: 《Cell Regeneration》2023年第1期52-52,共1页Siting Wei Meng Li Wanlu Song Jiaye Liu Shicheng Yu Yalong Wang Mengxian Zhang Huijun Du Yuan Liu Huidong Liu Wei Fu Baojie Li Ye-Guang Chen; Correction:Cell Regen 12,30(2023).https://doi.org/10.1186/s13619-023-00174-7 Following publication of the original article(Wei et al.2023),it is reported that the“Availability of data and materials”section needs to ...; 关键词：al. EXPRESSING INJURY

The cyclooxygenase-expressing mesenchyme resists intestinal epithelial injury by paracrine signaling: 《Cell Regeneration》2023年第1期107-118,共12页Siting Wei Meng Li Wanlu Song Jiaye Liu Shicheng Yu Yalong Wang Mengxian Zhang Huijun Du Yuan Liu Huidong Liu Wei Fu Baojie Li Ye-Guang Chen; supported by grants from the National Natural Science Foundation of China(31988101);the Natural Science Foundation of Jiangxi Province(20224ACB209001).; Paracrine signals play pivotal roles in organ homeostasis.Mesenchymal stromal cells(MSCs)play a key role in regulating epithelium homeostasis in the intestine while their paracrine effects are poorly characterized.Her...; 关键词：COLITIS Intestinal mucosal barrier Mesenchymal stromal cells ORGANOIDS Prostaglandin E2

Clinical Use of COX-2 Inhibitors Containing Quinoline Heterocycle as a Selective Therapeutic Agents for Complementary Medicine: 《Clinical Complementary Medicine and Pharmacology》2023年第3期60-77,共18页Megha P.Ambatkar Nilesh R.Rarokar Pramod B.Khedekar; Inflammation represents an initial response of immune system and is involved in a number of biochemical inci-dents.Such incidents may multiply and further develop the provocative response.Over the past 15 years,variou...; 关键词：QUINOLINE HETEROCYCLE INFLAMMATION CYCLOOXYGENASE Natural COMPLEMENTARY NSAID COX-2 inhibitor

Hepatic COX1 loss leads to impaired autophagic flux and exacerbates nonalcoholic steatohepatitis被引量：2: 《Acta Pharmaceutica Sinica B》2023年第6期2628-2644,共17页Qian Yu Chang Li Qinghui Niu Jigang Wang Zhaodi Che Ke Lei He Ren Boyi Ma Yixing Ren Pingping Luo Zhuming Fan Huan Zhang Zhaohui Liu George L.Tipoe Jia Xiao; partly supported by National Natural Science Foundation of China(82125026 and 82122009);Natural Science Foundation of Shandong Province(ZR2022QH241 and ZR2020ZD11,China);Seed Fund for Basic Research of University Research Committee of The University of Hong Kong(20161159263,Hong Kong,China)。; The mechanisms underlying autophagic defects in nonalcoholic steatohepatitis(NASH)remain largely unknown.We aimed to elucidate the roles of hepatic cyclooxygenase 1(COX1)in autophagy and the pathogenesis of diet-induc...; 关键词：Autophagy Inflammation Lipid metabolism Nonalcoholic fatty liver disease Cyclooxygenase 1 Phosphatidylinositol 3-phosphate WD repeat domain Phosphoinositide interacting 2 Autophagosome maturation

Component Analysis of Shuanghuanglian Freeze-dried Powder and Its Effects on Human Hepatocyte Function when Combined with Cefradine: 《Medicinal Plant》2022年第6期44-48,共5页Junlong YU Dazhi XU Ruyan WEN Xiangling LI; Guangxi Natural Science(2018GXNSFBA-050051);Doctor Initiation Fund Project of Guangxi University of Traditional Chinese Medicine(2020BS011)。; [Objectives]To detect the contents of components in Shuanghuanglian freeze-dried powder and to explore the effects of Shuanghuanglian freeze-dried powder and its components on human hepatocytes(HL-7702)alone or in com...; 关键词：Shuanghuanglian freeze-dried powder CEFRADINE HL-7702 Alanine aminotransferase Aspartate aminotransferase Adenosine diphosphate Adenosine triphosphate Cyclooxygenase 2 Heme oxygenase-1

Recent development on COX-2 inhibitors as promising anti-inflammatory agents:The past 10 years被引量：10: 《Acta Pharmaceutica Sinica B》2022年第6期2790-2807,共18页Zhiran Ju Menglan Li Junde Xu Daniel C.Howell Zhiyun Li Fen-Er Chen; Cyclooxygenases play a vital role in inflammation and are responsible for the production of prostaglandins.Two cyclooxygenases are described,the constitutive cyclooxygenase-1 and the inducible cyclooxygenase-2,for whi...; 关键词：INFLAMMATION CYCLOOXYGENASE PROSTAGLANDINS Adverse effects COX-2 inhibitors

Panax Notoginseng Saponin Attenuates Gastric Mucosal Epithelial Cell Injury Induced by Dual Antiplatelet Drugs through COX and PI3K/Akt/ VEGF-GSK-3β-RhoA Network Pathway被引量：5: 《Chinese Journal of Integrative Medicine》2021年第11期819-824,共6页WANG Ming-ming XUE Mei XIN Zhong-hai WANG Yan-hui LI Rui-jie JIANG Hong-yan SHI Da-zhuo; Supported by the National Natural Science Foundation of China(No.81273933 and 81102722);the Eleven Five-Year Plan of National Science and Technology Support Project(No.2006BAI04A01-2);the Jilin Province Major Science and Technology Achievement Transforming Project(No.11ZDZH005)。; Objective To elucidate the underlying mechanism of Panax notoginseng saponin(PNS)on gastric epithelial cell injury and barrier dysfunction induced by dual antiplatelet(DA).Methods Human gastric mucosal epithelial cell...; 关键词：Panax notoginseng saponins dual antiplatelet permeability CYCLOOXYGENASE PI3K

High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury被引量：9: 《Neural Regeneration Research》2021年第9期1848-1855,共8页Hong-Hua Song Tian-Cheng Song Ting Yang Chun-Shuai Sun Bing-Qiang He Hui Li Ying-Jie Wang Yu Li Hao Wu Yu-Ming Hu Yong-Jun Wang; supported by the National Key Research and Development Program of China,No.2018YFC1105603(to YJunW);the National Natural Science Foundation of China,No.31871211(to YJunW);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)(to YJunW);the China Postdoctoral Science Foundation,No.2020M681689(to YMH);the Basic Scientific Research Projects of Nantong of China,No.JC2018065(to HHS)。; High mobility group box 1(HMGB1) interacts with pattern-recognition receptors of immune cells to activate the inflammatory response. Astrocytes play a positive role in the inflammatory response of the central nervous ...; 关键词：ASTROCYTES COX2 HMGB1 inflammation spinal cord injury

Congestive heart failure in COX2 deficient rats被引量：3: 《Science China(Life Sciences)》2021年第7期1068-1076,共9页Qiangyou Wan Deping Kong Qian Liu Shumin Guo Chenchen Wang Yan Zhao Zun-Ji Ke Ying Yu; supported by the National Natural Science Foundation of China(81790623 and 81525004);the Chinese Ministry of Science and Technology(2017YFC1307404 and 2017YFC1307402)。; Non-steroidal anti-inflammatory drugs(NSAIDs)inhibit prostaglandin(PG)formation by targeting cyclooxygenase(COX)1 and 2.Long-term use of NSAIDs that selectively inhibit COX2 increases the risk for thrombotic events,ca...; 关键词：NSAID CYCLOOXYGENASE PROSTAGLANDIN heart failure energy metabolism

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