Acute myeloid leukemia(AML) and its treatment have remained, for long, an area of slow but constant therapeutic progress as well as of permanent frustration. Chemotherapy has initially been and still is part of the ba...
Inflammatory diseases are often chronic and recurrent,and current treatments do not typically remove underlying disease drivers1.T cells participate in a wide range of inflammatory diseases such as psoriasis2,Crohn's ...
Cognitive-oriented work on simile has developed out of attempts to pinpoint features distinguishing simile and metaphor.This development has had such consequences as 1)focusing on simile as an analogy-based process an...
supported by the National Key Research and Development Program of China(2022YFC2304100 and 2021YFA1201003).
Viral infectious clones(ICs)serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics.However,the molecular profiles and complex limitations of human coronaviruses(HCoV...
supported by the National Natural Science Foundation of China(5201101621)。
Leaves are the main organ for photosynthesis and organic synthesis in cotton.Leaf shape has important effects on photosynthetic efficiency and canopy formation,thereby affecting cotton yield.Previous studies have show...
supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China(32271546);the Innovation Program of Chinese Academy of Agriculture Sciences(CAAS-CSCB-202402);the Natural Science Foundation of Hubei ProvinceNatural Science Foundation of Hubei Province(2022CFB482).
Root-knot nematodes(RKNs)are plant pests that infect the roots of host plants.Bacillus thuringiensis(Bt)nematicidal proteins exhibited toxicity to nematodes.However,the application of nematicidal proteins for plant pr...
the National Key Research and Development Program of China(Grant No.2020YFA0909000);the National Natural Science Foundation of China(Grant Nos.82372014,82001878,and 82071961);the Shen Kang-United Imaging Joint Research and Development Plan(Grant No.SKLY2022CRT301).
Fibroblast activation protein (FAP) is among the most popular targets in nuclear medicine imaging and cancer theranostics. Several small-molecule moieties (FAPI-04, FAPI-46, etc.) are used for developing FAP-targeted ...
the National Natural Science Foundation of China(31930057 and 32330047 to F.W.;31970689 to J.M.;31701034,32171166,and 82030003 to Q.W.);the Natural Science Foundation of Henan Province of China(202300410169 to X.Y.).
Histone deacetylases(HDACs)are epigenetic regulators that play an important role in determining cell fate and maintaining cellular homeostasis.However,whether and how HDACs regulate iron metabolism and ferroptosis(an ...
funded by the National Key Research and Development Program of China(No.2021YFB3800800)to LT and DC;the National Natural Science Foundation of China(NSFC,No.82030067,82161160342,82250710174)to DC;the Hong Kong RGC grant(China)(HKU-17101821)to WWL and DC.
In mammals,skeletal bone development begins at hyaline cartilage formation at the early embryonic stage.1Then osteoblasts from the periosteum,which are distributed surrounding the hyaline cartilage,build up compact bo...